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[175767_at] potassium channel protein

Description g7739756 /REP_DB=GenBank Identifier /GB=AF257518.1 /PROTEIN_GB=AAF68999.1 /CHR=3 /FEA=Mapped Transcript /DEF=HERG-like potassium channel
Cluster 6grp_total > 19      4grp_total > 04      6grp_cgc > 01      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 12.3
(0)
A 		6.3
(-3)
A 		9.6
(-1.3)
A 		18.2
(3)
A 		12
B 9
(3)
A 		8.8
(2.7)
A 		7.7
(1)
A 		5.1
(-3)
A 		4
C 14.7
(-1.4)
A 		12.2
(-1.9)
A 		6.4
(-3)
A 		38.1
(3)
A 		32
avr 12
(-1) 		9.1
(-2.4) 		7.9
(-3) 		20.5
(3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 23
1 2 3 4 5 6 range
A 16
(0.4)
A 		9.6
(-1.3)
A 		4.3
(-2.8)
A 		9.2
(-1.4)
A 		25.3
(3)
A 		3.5
(-3)
A 		22
B 26.8
(3)
A 		8.2
(-1.9)
A 		4.3
(-2.9)
A 		5.9
(-2.5)
A 		5.5
(-2.6)
A 		4.1
(-3)
A 		23
C 15.9
(3)
A 		5.7
(-2.1)
A 		4
(-3)
A 		10.1
(0.1)
A 		5.1
(-2.4)
A 		8.5
(-0.7)
A 		12
avr 19.6
(3) 		7.8
(-1.6) 		4.2
(-3) 		8.4
(-1.4) 		12
(0) 		5.4
(-2.5) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5
1 2 3 4 range
A 4.5
(3)
A 		1.4
(-3)
A 		2.5
(-0.9)
A 		2.7
(-0.5)
A 		3
B 2.9
(3)
A 		2.2
(0.7)
A 		1.8
(-0.7)
A 		1.1
(-3)
A 		2
C 4.9
(0.9)
A 		3.5
(-1.1)
A 		2.2
(-3)
A 		6.4
(3)
A 		4
avr 4.1
(3) 		2.4
(-2.4) 		2.2
(-3) 		3.4
(0.8) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8
1 2 3 4 5 6 range
A 3
(-1.1)
A 		3.4
(-0.8)
A 		0.9
(-3)
A 		2.3
(-1.7)
A 		7.6
(3)
A 		0.9
(-3)
A 		7
B 9.3
(3)
A 		2.7
(-1.8)
A 		1
(-3)
A 		1.6
(-2.6)
A 		2.2
(-2.1)
A 		1.5
(-2.6)
A 		8
C 5.9
(3)
A 		1.7
(-2.1)
A 		1
(-3)
A 		2
(-1.8)
A 		1.6
(-2.3)
A 		2.8
(-0.8)
A 		5
avr 6.1
(3) 		2.6
(-1.1) 		1
(-3) 		2
(-1.8) 		3.8
(0.3) 		1.7
(-2.2) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175767_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19780
Sequence Type Exemplar sequence
Representative Public ID 7739756 NCBI
Target Description g7739756 /REP_DB=GenBank Identifier /GB=AF257518.1 /PROTEIN_GB=AAF68999.1 /CHR=3 /FEA=Mapped Transcript /DEF=HERG-like potassium channel
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065423(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065423 NCBI Caenorhabditis elegans UNCoordinated family member (unc-103) (unc-103) mRNA, complete cds. 11/11 A 
SNAP00000043765 ENSEMBL cdna:SNAP chromosome:CEL140:III:4142879:4146418:1 11/11 None
GENEFINDER00000043786 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4142904:4146418:1 11/11 None
C30D11.1 ENSEMBL cdna:known chromosome:CEL140:III:4138683:4147226:1 gene:C30D11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4138682-4146418(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol unc-103
Ensembl C30D11.1
Entrez Gene 175527 Entrez gene
SwissProt Q18325 EMBL-EBI
WormBase CE27805 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.20108.1.S1_S_AT similar to potassium voltage-gated channel, subfamily H, member 6 isoform 1 cfa
DROSOPHILA_2:1629418_S_AT seizure dm
DROSGENOME1:152427_AT seizure dm
CHICKEN:GGA.13087.1.S1_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
CHICKEN:GGA.248.1.S1_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
CHICKEN:GGA.7592.1.S1_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 gga
HG-U133_PLUS_2:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:211045_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133_PLUS_2:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-FOCUS:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:221023_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133_PLUS_2:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U133A_2:211046_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBA:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBB:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBC:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HU35KSUBD:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HUGENEFL:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HC-G110:HUM_ALU_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:G13623462_3P_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:G13540548_3P_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
U133_X3P:221023_3P_S_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
HG-U95D:86319_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 hs
RN-U34:RC_AA894087_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RG-U34A:RC_AA894087_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RAE230A:1369017_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
RAT230_2:1369017_AT potassium voltage-gated channel, subfamily H (eag-related), member 6 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAC42257 Hypothetical protein C30D11.1 [Caenorhabditis elegans] emb|CAA84644.2| Hypothetical protein C30D11.1 [Caenorhabditis elegans] ref|NP_497824.1| UNCoordinated family member (unc-103) [Caenorhabditis elegans] gb|AAF68999.1| HERG-like potassium channel [Caenorhabditis elegans] 0.0
blast CAE72879 Hypothetical protein CBG20190 [Caenorhabditis briggsae] 0.0
blast XP_393977 PREDICTED: similar to ENSANGP00000009272 [Apis mellifera] 0.0
blast CAC42257 Hypothetical protein C30D11.1 [Caenorhabditis elegans] emb|CAA84644.2| Hypothetical protein C30D11.1 [Caenorhabditis elegans] ref|NP_497824.1| UNCoordinated family member (unc-103) [Caenorhabditis elegans] gb|AAF68999.1| HERG-like potassium channel [Caenorhabditis elegans] 1.0E-148
blast CAC42257 Hypothetical protein C30D11.1 [Caenorhabditis elegans] emb|CAA84644.2| Hypothetical protein C30D11.1 [Caenorhabditis elegans] ref|NP_497824.1| UNCoordinated family member (unc-103) [Caenorhabditis elegans] gb|AAF68999.1| HERG-like potassium channel [Caenorhabditis elegans] 1.0E-139
blast CAE72879 Hypothetical protein CBG20190 [Caenorhabditis briggsae] 1.0E-121
blast CAE72879 Hypothetical protein CBG20190 [Caenorhabditis briggsae] 1.0E-111
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 1.8E-33
Pfam IPR000595 EMBL-EBI Cyclic nucleotide-binding domain 3.1E-24
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497824.1 4 85-107,225-247,289-311,318-340
C30D11.1 4 85-107,225-247,289-311,318-340
Sequence
Target Sequence 
>C. ELEGANS:175767_AT
gtgctgaatcagtttctcgatgtgattcaaatcccatcgataggaggcagtcagccggat
cgaggagctcgtctcgttgctcacccccacacgctgctctcactgcaacccgatctgaag
ctactccattactccgaagatcgacgaatcatcatgaggaagatgacgcattgtttgatg
atatcagagcatttgcacgtggaaatacagtaacaatgtctccaacggttgctggtaatt
cagtgtctccaacaacggcaattcataatgatgggatacattcacagcaattgagcgacc
gatcagatgattatgaagaacgaagggcaaacatgtttggaaggaggcttgaatcaattg
aaagccaaatggaacgaatgcagaacaagtttaatagtgatatggagacattgatcaaac
ttgtaaaagagcaatcgataatccgaaacaatggatcatcaaatgaagagcccaatgccc
gttaccgtccgaacaactacatatcgtcagcgatacgtcttccgaatggaggtggtggtg
gagttgtcgatgagatgagagtctcgaggctctcatcacacgagccac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGCTGAATCAGTTTCTCGATGTGA 88 479 1766 Antisense
CAGTCAGCCGGATCGAGGAGCTCGT 371 207 1813 Antisense
TCACTGCAACCCGATCTGAAGCTAC 489 625 1865 Antisense
CTACTCCATTACTCCGAAGATCGAC 147 227 1886 Antisense
GTAACAATGTCTCCAACGGTTGCTG 406 461 1975 Antisense
GGTTGCTGGTAATTCAGTGTCTCCA 497 507 1992 Antisense
GTGTCTCCAACAACGGCAATTCATA 596 485 2008 Antisense
AAATGAAGAGCCCAATGCCCGTTAC 282 119 2226 Antisense
GTTACCGTCCGAACAACTACATATC 91 447 2246 Antisense
GTCAGCGATACGTCTTCCGAATGGA 647 461 2271 Antisense
TCGAGGCTCTCATCACACGAGCCAC 503 603 2329 Antisense
Sequence Source GenBank