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[175766_s_at] PROTEIN-TYROSINE PHOSPHATASE

Description g2323369 /REP_DB=GenBank Identifier /GB=AF015882.1 /PROTEIN_GB=AAC21678.1 /CHR=2 /FEA=Mapped Transcript /DEF=protein tyrosine phosphatase
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 56      4grp_highest_8_8 > 34      4grp_high_8_8 > 57      6grp_highest_nonorm > 74      6grp_total > 57      4grp_total > 63      6grp_highest_sub > Cu      6grp_cgc > 27      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 608
1 2 3 4 range
A 1058.5
(3)
P 		599.8
(-1.5)
P 		836
(0.8)
P 		450.6
(-3)
P 		608
B 650.6
(-3)
P 		757.6
(3)
P 		711.3
(0.4)
P 		756.5
(2.9)
P 		107
C 826
(2.9)
P 		601.1
(-3)
P 		831.2
(3)
P 		607.8
(-2.8)
P 		230
avr 845
(3) 		652.8
(-1.8) 		792.8
(1.7) 		605
(-3) 		240

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 363
1 2 3 4 5 6 range
A 604.4
(-3)
P 		719.3
(-0.7)
P 		605
(-3)
P 		692.6
(-1.2)
P 		707.4
(-0.9)
P 		902.4
(3)
P 		298
B 854.8
(3)
P 		685.2
(-0.2)
P 		556.9
(-2.7)
P 		667
(-0.6)
P 		539.8
(-3)
P 		812.6
(2.2)
P 		315
C 854.2
(3)
P 		699.3
(-0.4)
P 		803.3
(1.9)
P 		849.6
(2.9)
P 		582.6
(-3)
P 		805
(1.9)
P 		272
avr 771.1
(1.2) 		701.3
(-0.6) 		655.1
(-1.8) 		736.4
(0.3) 		609.9
(-3) 		840
(3) 		230
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 319
1 2 3 4 range
A 385.4
(3)
P 		130.2
(-1.8)
P 		218.5
(-0.1)
P 		66
(-3)
P 		319
B 207.5
(3)
P 		187.1
(0.4)
P 		164.8
(-2.5)
P 		161.2
(-3)
P 		46
C 273.4
(2.5)
P 		172.8
(-0.7)
P 		289.7
(3)
P 		102.5
(-3)
P 		187
avr 288.8
(3) 		163.4
(-1.2) 		224.3
(0.8) 		109.9
(-3) 		179

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 205
1 2 3 4 5 6 range
A 111.4
(-3)
P 		255.8
(3)
P 		131.8
(-2.2)
P 		175.7
(-0.3)
P 		213.5
(1.2)
P 		219.7
(1.5)
P 		144
B 297.4
(2.8)
P 		228.1
(0.3)
P 		135.2
(-3)
P 		176.7
(-1.5)
P 		219.3
(0)
P 		303
(3)
P 		168
C 316.6
(3)
P 		213.4
(-1.2)
P 		204.5
(-1.6)
P 		170.8
(-3)
P 		188.5
(-2.3)
P 		269.5
(1.1)
P 		146
avr 241.8
(1.7) 		232.4
(1.2) 		157.2
(-3) 		174.4
(-2) 		207.1
(-0.2) 		264.1
(3) 		107
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175766_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19731
Sequence Type Exemplar sequence
Representative Public ID 2323369 NCBI
Target Description g2323369 /REP_DB=GenBank Identifier /GB=AF015882.1 /PROTEIN_GB=AAC21678.1 /CHR=2 /FEA=Mapped Transcript /DEF=protein tyrosine phosphatase
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062783(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062783 NCBI Caenorhabditis elegans Protein Tyrosine Phosphatase family member (ptp-2) (ptp-2) mRNA, complete cds. 11/11 A 
F59G1.5.2 ENSEMBL cdna:known chromosome:CEL140:II:5918589:5921580:1 gene:F59G1.5 11/11 None
F59G1.5.1 ENSEMBL cdna:known chromosome:CEL140:II:5918610:5921580:1 gene:F59G1.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5918605-5921578(+) 100.0 100.0
Public Domain and Genome References
Gene Title PROTEIN-TYROSINE PHOSPHATASE
Gene Symbol ptp-2
Ensembl F59G1.5
Entrez Gene 174003 Entrez gene
SwissProt Q21055 EMBL-EBI
WormBase CE02705 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1605771_AT similar to protein tyrosine phosphatase, non-receptor type 11 cfa
CANINE_2:CFAAFFX.14053.1.S1_AT similar to protein tyrosine phosphatase, non-receptor type 11 cfa
CHICKEN:GGA.482.1.S1_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) gga
HG-U95AV2:1870_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HC-G110:1870_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95AV2:1871_G_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HC-G110:1871_G_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A:205867_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:205867_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A_2:205867_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A:205868_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:205868_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-FOCUS:205868_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A_2:205868_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A:209895_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A_2:209895_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:209895_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:209896_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A_2:209896_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A:209896_S_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A_2:212610_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133A:212610_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:212610_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HUGENEFL:U79291_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HUGENEFL:D13540_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
U133_X3P:G7770146_RC_3P_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
U133_X3P:G292406_3P_A_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
U133_X3P:G13430845_3P_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
U133_X3P:HS2.22868.1.S1_3P_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
U133_X3P:HS.83572.0.S1_3P_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U133_PLUS_2:1552637_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95AV2:38443_AT protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95E:76756_I_AT Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95E:76759_R_AT Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95D:81420_AT Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
HG-U95D:91527_AT Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) hs
MOE430A:1427699_A_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430A_2:1427699_A_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430_2:1427699_A_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430A_2:1421196_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOE430A:1421196_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430_2:1421196_AT protein tyrosine phosphatase, non-receptor type 11 mm
MU11KSUBA:D84372_S_AT protein tyrosine phosphatase, non-receptor type 11 mm
MG-U74AV2:102874_AT protein tyrosine phosphatase, non-receptor type 11 mm
MG-U74BV2:114636_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOE430A:1451225_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430A_2:1451225_AT protein tyrosine phosphatase, non-receptor type 11 mm
MOUSE430_2:1451225_AT protein tyrosine phosphatase, non-receptor type 11 mm
MU19KSUBC:TC37289_AT Protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone IMAGE:3490108) mm
RG-U34A:U09307_AT protein tyrosine phosphatase, non-receptor type 11 rn
RG-U34A:U57499_AT protein tyrosine phosphatase, non-receptor type 11 rn
RG-U34A:U57499_G_AT protein tyrosine phosphatase, non-receptor type 11 rn
RG-U34B:RC_AI012725_S_AT protein tyrosine phosphatase, non-receptor type 11 rn
RAE230A:1387668_AT protein tyrosine phosphatase, non-receptor type 11 rn
RAT230_2:1387668_AT protein tyrosine phosphatase, non-receptor type 11 rn
RAE230B:1396927_AT Protein tyrosine phosphatase, non-receptor type 11 rn
RAT230_2:1396927_AT Protein tyrosine phosphatase, non-receptor type 11 rn
RAE230B:1396948_AT Protein tyrosine phosphatase, non-receptor type 11 rn
RAT230_2:1396948_AT Protein tyrosine phosphatase, non-receptor type 11 rn
RG-U34A:RC_AI138070_AT Protein tyrosine phosphatase, non-receptor type 11 rn
RG-U34A:RC_AI171525_AT Protein tyrosine phosphatase, non-receptor type 11 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK31531 Protein tyrosine phosphatase protein 2 [Caenorhabditis elegans] ref|NP_495184.1| Protein Tyrosine Phosphatase family member (ptp-2) [Caenorhabditis elegans] gb|AAC21678.1| protein tyrosine phosphatase [Caenorhabditis elegans] 0.0
blast CAE59221 Hypothetical protein CBG02539 [Caenorhabditis briggsae] 0.0
blast XP_395984 PREDICTED: similar to ENSANGP00000001164 [Apis mellifera] 2.0E-97
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 2.2E-14
Pfam IPR000980 EMBL-EBI SH2 motif 1.4E-17
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.3E-115
Sequence
Target Sequence 
>C. ELEGANS:175766_S_AT
tttcttgttccgtcgtaattattcgcaaattctctgcaacaccataccattcattgttga
gcactatgtactatttcccaccaattctttatataatcaagaacaaatcgcgacgctgtc
ttatgcacatgattcccccgaatcccatatccttccagaatgatagtagatca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTCTTGTTCCGTCGTAATTATTCG 554 671 2477 Antisense
TGTTCCGTCGTAATTATTCGCAAAT 163 563 2482 Antisense
TCTGCAACACCATACCATTCATTGT 566 607 2509 Antisense
ACACCATACCATTCATTGTTGAGCA 538 109 2515 Antisense
CATACCATTCATTGTTGAGCACTAT 674 211 2519 Antisense
TGAGCACTATGTACTATTTCCCACC 475 569 2534 Antisense
TTTCCCACCAATTCTTTATATAATC 702 669 2550 Antisense
AATCAAGAACAAATCGCGACGCTGT 5 171 2571 Antisense
GAATCCCATATCCTTCCAGAATGAT 680 329 2616 Antisense
ATCCCATATCCTTCCAGAATGATAG 397 37 2618 Antisense
ATCCTTCCAGAATGATAGTAGATCA 51 39 2625 Antisense
Sequence Source GenBank