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[175764_s_at]

Description g6467496 /REP_DB=GenBank Identifier /GB=AF173172.1 /PROTEIN_GB=AAF13165.1 /CHR=2 /FEA=Mapped Transcript /DEF=CLC chloride channel protein
Cluster 6grp_total > 77      4grp_total > 04      6grp_cgc > 48      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 194
1 2 3 4 range
A 38.6
(-2.1)
A 		9.3
(-3)
A 		21.5
(-2.6)
A 		200.1
(3)
P 		191
B 50.2
(-1.5)
A 		26.8
(-2.3)
A 		5.7
(-3)
A 		187.1
(3)
P 		181
C 85.1
(-1)
P 		29.4
(-3)
A 		46.5
(-2.4)
A 		196.4
(3)
P 		167
avr 58
(-1.7) 		21.8
(-3) 		24.6
(-2.9) 		194.5
(3) 		173

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 159
1 2 3 4 5 6 range
A 14.5
(-3)
A 		60.5
(-1.1)
P 		61.7
(-1)
A 		81.6
(-0.2)
P 		75.8
(-0.5)
A 		159.1
(3)
P 		145
B 48
(-2)
A 		50.6
(-1.8)
A 		27
(-3)
A 		48.7
(-1.9)
A 		48.9
(-1.9)
A 		148.7
(3)
P 		122
C 91.5
(-0.7)
P 		70.9
(-1.6)
A 		40.8
(-3)
A 		56.5
(-2.3)
A 		84.8
(-1)
P 		173.7
(3)
P 		133
avr 51.3
(-2.6) 		60.7
(-2.1) 		43.2
(-3) 		62.3
(-2) 		69.8
(-1.6) 		160.5
(3) 		117
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 14.1
(-0.3)
A 		2
(-3)
A 		5.6
(-2.2)
A 		29.3
(3)
P 		27
B 16
(-0.7)
A 		6.6
(-2.2)
A 		1.3
(-3)
A 		39.9
(3)
P 		39
C 28.2
(1.8)
P 		8.4
(-3)
A 		16.2
(-1.1)
A 		33.1
(3)
P 		25
avr 19.4
(-0.1) 		5.7
(-3) 		7.7
(-2.6) 		34.1
(3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 2.7
(-3)
A 		21.5
(0.1)
P 		13.4
(-1.2)
A 		20.7
(0)
P 		22.9
(0.4)
A 		38.7
(3)
P 		36
B 16.7
(-1.7)
A 		16.8
(-1.7)
A 		6.5
(-3)
A 		12.9
(-2.2)
A 		19.9
(-1.4)
A 		55.4
(3)
P 		49
C 33.9
(-0.1)
P 		21.6
(-1.6)
A 		10.4
(-3)
A 		11.4
(-2.9)
A 		27.4
(-0.9)
P 		58.2
(3)
P 		48
avr 17.8
(-1.9) 		20
(-1.5) 		10.1
(-3) 		15
(-2.3) 		23.4
(-1) 		50.8
(3) 		41
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175764_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19735
Sequence Type Exemplar sequence
Representative Public ID 6467496 NCBI
Target Description g6467496 /REP_DB=GenBank Identifier /GB=AF173172.1 /PROTEIN_GB=AAF13165.1 /CHR=2 /FEA=Mapped Transcript /DEF=CLC chloride channel protein
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026889(11), NM_001026890(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026889 NCBI Caenorhabditis elegans CLC-type chloride cHannel family member (clh-3) (clh-3) mRNA, complete cds. 11/11 None
NM_001026890 NCBI Caenorhabditis elegans CLC-type chloride cHannel family member (clh-3) (clh-3) mRNA, complete cds. 11/11 None
E04F6.11a ENSEMBL cdna:known chromosome:CEL140:II:7217886:7222985:-1 gene:E04F6.11 11/11 A 
E04F6.11b ENSEMBL cdna:known chromosome:CEL140:II:7219073:7225579:-1 gene:E04F6.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7218974-7225853(-) 100.0 100.0
Public Domain and Genome References
Ensembl E04F6.11
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAK68291 Clc-type chloride channel protein 3, isoform a [Caenorhabditis elegans] ref|NP_001022060.1| CLC-type chloride cHannel family member (clh-3) [Caenorhabditis elegans] gb|AAG49524.1| CLC-type chloride channel CLH-3b [Caenorhabditis elegans] 0.0
blast T15915 hypothetical protein E04F6.11 - Caenorhabditis elegans 0.0
blast AAK68292 Clc-type chloride channel protein 3, isoform b [Caenorhabditis elegans] ref|NP_001022061.1| CLC-type chloride cHannel family member (clh-3) [Caenorhabditis elegans] gb|AAF13165.1| CLC chloride channel protein [Caenorhabditis elegans] 0.0
blast CAE67575 Hypothetical protein CBG13104 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000644 EMBL-EBI CBS domain 4.8E-6
Pfam IPR000644 EMBL-EBI CBS domain 2.4E-5
Pfam IPR001807 EMBL-EBI Cl- channel, voltage gated 1.0E-126
Pfam IPR000644 EMBL-EBI CBS domain 4.8E-6
Pfam IPR000644 EMBL-EBI CBS domain 2.0E-4
Pfam IPR001807 EMBL-EBI Cl- channel, voltage gated 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001022060.1 9 52-74,94-116,202-224,283-305,326-348,406-428,433-455,475-497,504-526
NP_001022061.1 9 123-145,165-187,273-295,354-376,397-419,477-499,504-526,546-568,575-597
E04F6.11a 9 52-74,94-116,202-224,283-305,326-348,406-428,433-455,475-497,504-526
E04F6.11b 9 123-145,165-187,273-295,354-376,397-419,477-499,504-526,546-568,575-597
Sequence
Target Sequence 
>C. ELEGANS:175764_S_AT
aacccggatcagagcttttcctttggttgaaaatatggaatcactagctcttgtcggttc
ggtcagtagaagtcagctgcaacgatacgtcgattctcaaattggaacaaaagcccgatt
tgcagaagcaactcgtagaatcaaacaacgtttggaagatgaagaaagcgaacgaaaaag
aagagaagaaagtaaatcagatgatacagaagatagtttggaaacgacaggtgctggaga
gagaagagctagtcggtatgaatgggaggatatgatgctcaatcaaaagctggatttgag
ccaacttgatattgattctacgccattccaactcagtgaatatacgagtttattcaaggc
tcattctctattctcacttcttggtctaaatcgtgcatacgtgacgaaaaaagggcaatt
gattggcgttgtcgcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACCCGGATCAGAGCTTTTCCTTTG 703 145 2098 Antisense
TATGGAATCACTAGCTCTTGTCGGT 551 655 2131 Antisense
GCTCTTGTCGGTTCGGTCAGTAGAA 623 299 2144 Antisense
GAAGTCAGCTGCAACGATACGTCGA 221 337 2166 Antisense
ACGATACGTCGATTCTCAAATTGGA 666 93 2179 Antisense
AGCCCGATTTGCAGAAGCAACTCGT 65 83 2209 Antisense
GCCAACTTGATATTGATTCTACGCC 79 279 2397 Antisense
TTCTACGCCATTCCAACTCAGTGAA 425 689 2413 Antisense
TCTATTCTCACTTCTTGGTCTAAAT 187 615 2464 Antisense
TTCTTGGTCTAAATCGTGCATACGT 74 689 2475 Antisense
GGGCAATTGATTGGCGTTGTCGCAT 368 493 2510 Antisense
Sequence Source GenBank