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[175763_at]

Description g6467494 /REP_DB=GenBank Identifier /GB=AF173171.1 /PROTEIN_GB=AAF13164.1 /CHR=2 /FEA=Mapped Transcript /DEF=CLC chloride channel protein
Cluster 6grp_highest_10_10 > 81      6grp_high1_10_10 > 29      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 60      6grp_total > 28      4grp_total > 30      6grp_highest_sub > Cu      6grp_cgc > 04      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 571
1 2 3 4 range
A 784.3
(3)
P 		257.4
(-2.6)
P 		217
(-3)
P 		527.5
(0.3)
P 		567
B 637.2
(2.1)
P 		354.1
(-1.3)
P 		213
(-3)
P 		710.8
(3)
P 		498
C 720.6
(3)
P 		350.4
(-1.7)
P 		251.9
(-3)
P 		551
(0.8)
P 		469
avr 714
(3) 		320.6
(-1.8) 		227.3
(-3) 		596.4
(1.6) 		487

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 396
1 2 3 4 5 6 range
A 502.1
(3)
P 		436.4
(1.5)
P 		271.2
(-2.2)
P 		236.6
(-3)
P 		406.9
(0.8)
P 		301.5
(-1.5)
P 		266
B 629.1
(3)
P 		517.5
(1.1)
P 		280.7
(-3)
P 		291.9
(-2.8)
P 		336.9
(-2)
P 		386.7
(-1.2)
P 		348
C 587.1
(3)
P 		467.6
(1)
P 		233.1
(-3)
P 		258.2
(-2.6)
P 		384.8
(-0.4)
P 		400.4
(-0.2)
P 		354
avr 572.8
(3) 		473.8
(1.1) 		261.7
(-3) 		262.2
(-3) 		376.2
(-0.8) 		362.9
(-1) 		311
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 236
1 2 3 4 range
A 285.6
(3)
P 		55.9
(-3)
P 		56.7
(-3)
P 		77.2
(-2.4)
P 		230
B 203.2
(3)
P 		87.4
(-1.5)
P 		49.4
(-3)
P 		151.5
(1)
P 		154
C 238.6
(3)
P 		100.7
(-2.5)
P 		87.8
(-3)
P 		92.9
(-2.8)
P 		151
avr 242.5
(3) 		81.3
(-2.4) 		64.6
(-3) 		107.2
(-1.6) 		178

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 167
1 2 3 4 5 6 range
A 92.6
(-0.9)
P 		155.2
(3)
P 		59.1
(-3)
P 		60
(-2.9)
P 		122.8
(1)
P 		73.4
(-2.1)
P 		96
B 218.9
(3)
P 		172.3
(1.1)
P 		68.2
(-3)
P 		77.3
(-2.6)
P 		136.9
(-0.3)
P 		144.2
(0)
P 		151
C 217.6
(3)
P 		142.7
(0.3)
P 		59.3
(-2.7)
P 		51.9
(-3)
P 		124.5
(-0.4)
P 		134
(-0)
P 		166
avr 176.4
(3) 		156.7
(2) 		62.2
(-3) 		63.1
(-3) 		128.1
(0.5) 		117.2
(-0.1) 		114
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175763_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19719
Sequence Type Exemplar sequence
Representative Public ID 6467494 NCBI
Target Description g6467494 /REP_DB=GenBank Identifier /GB=AF173171.1 /PROTEIN_GB=AAF13164.1 /CHR=2 /FEA=Mapped Transcript /DEF=CLC chloride channel protein
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026728(11), NM_001026730(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026728 NCBI Caenorhabditis elegans CLC-type chloride cHannel family member (clh-2) (clh-2) mRNA, complete cds. 11/11 None
NM_001026730 NCBI Caenorhabditis elegans CLC-type chloride cHannel family member (clh-2) (clh-2) mRNA, complete cds. 11/11 None
B0491.8a ENSEMBL cdna:known chromosome:CEL140:II:11358353:11370149:1 gene:B0491.8 11/11 A 
B0491.8c ENSEMBL cdna:known chromosome:CEL140:II:11365298:11370196:1 gene:B0491.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
174738 3 2 NM_001026728 175763_at (11)
NM_001026730 175763_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11365292-11370193(+) 100.0 100.0
Public Domain and Genome References
Ensembl B0491.8
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA90092 Hypothetical protein B0491.8a [Caenorhabditis elegans] emb|CAA88325.1| Hypothetical protein B0491.8a [Caenorhabditis elegans] ref|NP_001021899.1| CLC-type chloride cHannel family member (clh-2) [Caenorhabditis elegans] gb|AAG49523.1| CLC-type chloride channel CLH-2b [Caenorhabditis elegans] 0.0
blast CAC42250 Hypothetical protein B0491.8b [Caenorhabditis elegans] emb|CAC42266.1| Hypothetical protein B0491.8b [Caenorhabditis elegans] ref|NP_001021900.1| CLC-type chloride cHannel family member (clh-2) [Caenorhabditis elegans] 0.0
blast CAE59522 Hypothetical protein CBG02916 [Caenorhabditis briggsae] 0.0
blast CAF31469 Hypothetical protein B0491.8c [Caenorhabditis elegans] emb|CAF31471.1| Hypothetical protein B0491.8c [Caenorhabditis elegans] ref|NP_001021901.1| CLC-type chloride cHannel family member (clh-2) [Caenorhabditis elegans] gb|AAF13164.1| CLC chloride channel protein [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000644 EMBL-EBI CBS domain 2.5E-4
Pfam IPR000644 EMBL-EBI CBS domain 5.7E-4
Pfam IPR001807 EMBL-EBI Cl- channel, voltage gated 1.0E-126
Pfam IPR000644 EMBL-EBI CBS domain 2.5E-4
Pfam IPR000644 EMBL-EBI CBS domain 5.7E-4
Pfam IPR001807 EMBL-EBI Cl- channel, voltage gated 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001021899.1 11 85-107,127-149,178-197,235-257,270-292,319-338,359-381,433-455,462-484,499-521,533-555
NP_001021901.1 11 54-76,96-118,147-166,204-226,239-261,288-307,328-350,397-419,426-448,463-485,497-519
B0491.8a 11 85-107,127-149,178-197,235-257,270-292,319-338,359-381,433-455,462-484,499-521,533-555
B0491.8c 11 54-76,96-118,147-166,204-226,239-261,288-307,328-350,397-419,426-448,463-485,497-519
Sequence
Target Sequence 
>C. ELEGANS:175763_AT
attcaatttttctcaactacgcacttttgttttccttttggtttctacaaacctatttat
caaagttgtcatttctcatttcaagatctcattttataactttctagtcaaccaaccgaa
acaattagggttagaagcacttccaatctacaggttataatgttttcccccagtacctta
ttttctagctctcggtgtttaaatttttattttctttttaagaaaaaaagcgataggctt
ttcttttggttact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTCAATTTTTCTCAACTACGCACT 164 13 2588 Antisense
TCAACTACGCACTTTTGTTTTCCTT 416 629 2600 Antisense
GTTTCTACAAACCTATTTATCAAAG 640 449 2628 Antisense
GTCATTTCTCATTTCAAGATCTCAT 576 467 2655 Antisense
GATCTCATTTTATAACTTTCTAGTC 29 419 2672 Antisense
TCTAGTCAACCAACCGAAACAATTA 584 611 2690 Antisense
GAAGCACTTCCAATCTACAGGTTAT 510 341 2721 Antisense
TACAGGTTATAATGTTTTCCCCCAG 572 609 2736 Antisense
CCAGTACCTTATTTTCTAGCTCTCG 601 271 2757 Antisense
TCTAGCTCTCGGTGTTTAAATTTTT 275 553 2771 Antisense
GCGATAGGCTTTTCTTTTGGTTACT 427 289 2817 Antisense
Sequence Source GenBank