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[175738_s_at]

Description g5002205 /REP_DB=GenBank Identifier /GB=AF143243.1 /PROTEIN_GB=AAD37360.1 /CHR=3 /FEA=Mapped Transcript /DEF=protein kinase LIT-1a
Cluster 6grp_highest_10_10 > 90      6grp_high1_10_10 > 09      4grp_highest_8_8 > 07      4grp_high_8_8 > 21      6grp_highest_nonorm > 20      6grp_total > 04      4grp_total > 18      6grp_cgc > 02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1123
1 2 3 4 range
A 881.2
(-3)
P 		1083.2
(-1.8)
P 		920
(-2.8)
P 		1910.2
(3)
P 		1029
B 833.5
(-2.7)
P 		1097.5
(-0.9)
P 		789.6
(-3)
P 		1674.7
(3)
P 		885
C 787.4
(-3)
P 		1056.5
(-1.2)
P 		936.5
(-2)
P 		1690.7
(3)
P 		903
avr 834
(-3) 		1079.1
(-1.4) 		882
(-2.7) 		1758.5
(3) 		925

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 777
1 2 3 4 5 6 range
A 1419.2
(3)
P 		1218.8
(0.9)
P 		902
(-2.4)
P 		842.2
(-3)
P 		1320.5
(2)
P 		922.2
(-2.2)
P 		577
B 1379.8
(3)
P 		1155.7
(1.2)
P 		642.5
(-3)
P 		1299.9
(2.3)
P 		1120.3
(0.9)
P 		829.1
(-1.5)
P 		737
C 1287.8
(3)
P 		1286.7
(3)
P 		872.5
(-1.9)
P 		1175.3
(1.7)
P 		1158.5
(1.5)
P 		777.3
(-3)
P 		511
avr 1362.3
(3) 		1220.4
(1.5) 		805.7
(-3) 		1105.8
(0.2) 		1199.8
(1.2) 		842.9
(-2.6) 		557
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 174
1 2 3 4 range
A 320.8
(3)
P 		235.1
(-3)
P 		240.5
(-2.6)
P 		279.6
(0.1)
P 		86
B 265.8
(-0.1)
P 		271
(0)
P 		183
(-3)
P 		356.9
(3)
P 		174
C 260.6
(-3)
P 		303.7
(0.9)
P 		326.4
(3)
P 		285.1
(-0.8)
P 		66
avr 282.4
(0.4) 		269.9
(-0.9) 		250
(-3) 		307.2
(3) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 324
1 2 3 4 5 6 range
A 261.6
(-1.4)
P 		433.5
(3)
P 		196.4
(-3)
P 		213.6
(-2.6)
P 		398.5
(2.1)
P 		224.5
(-2.3)
P 		237
B 480.1
(3)
P 		384.7
(1.2)
P 		156
(-3)
P 		344.3
(0.5)
P 		455.1
(2.5)
P 		309.2
(-0.2)
P 		324
C 477.3
(3)
P 		392.6
(1)
P 		222.1
(-3)
P 		236.4
(-2.7)
P 		374.9
(0.6)
P 		260.2
(-2.1)
P 		255
avr 406.3
(2.9) 		403.6
(2.8) 		191.5
(-3) 		264.8
(-1) 		409.5
(3) 		264.6
(-1) 		218
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175738_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19751
Sequence Type Exemplar sequence
Representative Public ID 5002205 NCBI
Target Description g5002205 /REP_DB=GenBank Identifier /GB=AF143243.1 /PROTEIN_GB=AAD37360.1 /CHR=3 /FEA=Mapped Transcript /DEF=protein kinase LIT-1a
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001027637(11), NM_001027635(11), NM_001027638(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001027637 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027635 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
NM_001027638 NCBI Caenorhabditis elegans Loss of InTestine family member (lit-1) (lit-1) mRNA, complete cds. 11/11 None
W06F12.1d ENSEMBL cdna:known chromosome:CEL140:III:13701509:13723917:1 gene:W06F12.1 11/11 A 
W06F12.1b ENSEMBL cdna:known chromosome:CEL140:III:13717369:13723917:1 gene:W06F12.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
176808 5 3 NM_001027635 175738_s_at (11)
NM_001027637 175738_s_at (11)
NM_001027638 175738_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13714086-13723585(+) 100.0 100.0
Public Domain and Genome References
Ensembl W06F12.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAH10786 Hypothetical protein W06F12.1d [Caenorhabditis elegans] emb|CAH10804.1| Hypothetical protein W06F12.1d [Caenorhabditis elegans] ref|NP_001022808.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] 0.0
blast CAB05827 Hypothetical protein W06F12.1a [Caenorhabditis elegans] ref|NP_001022805.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] gb|AAD39815.1| LIT-1 [Caenorhabditis elegans] 0.0
blast CAB60300 Hypothetical protein W06F12.1b [Caenorhabditis elegans] ref|NP_001022806.1| Loss of InTestine family member (lit-1) [Caenorhabditis elegans] gb|AAD37361.1| protein kinase LIT-1b [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-70
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 6.0E-72
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 3.0E-72
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 8.0E-73
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Pfam IPR000719 EMBL-EBI Protein kinase 3.5E-83
Sequence
Target Sequence 
>C. ELEGANS:175738_S_AT
ttgccccacgtgtaattattgattggcaaatcgcgtcccccgccactctatgagcttttt
atgtgatccttcaacaaaagttttttgaaatatcccatttagttattgattttcctattc
ttcttgtgattgtgctggtcgcttttgcatcaaaagtgcgtcttctcttcttcttaaagg
tgcccctctttcaaaacaaaaaatgccacagttctttcaaaaatgtctcccattttcccc
tattctttttttggtcgtatacatcacggtgaatttcgtttcaaagatttttatgttttt
tttcttaaatgtattttcttaacttatatatgtatatcactcaaaaatctcgtccttttt
ctcatctacataacttgaaaatttttgtttcatgtttcattttccccactcccgaatgcc
ccaagtgtctttcaacttcaaaaaatctgcttgtttcattttttccactg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGCCCCACGTGTAATTATTGATTG 466 701 1856 Antisense
TTATTGATTGGCAAATCGCGTCCCC 439 679 1871 Antisense
GAGCTTTTTATGTGATCCTTCAACA 40 381 1907 Antisense
TCCTATTCTTCTTGTGATTGTGCTG 49 593 1968 Antisense
ATTGTGCTGGTCGCTTTTGCATCAA 197 5 1984 Antisense
CATCAAAAGTGCGTCTTCTCTTCTT 287 213 2003 Antisense
TTCTCTTCTTCTTAAAGGTGCCCCT 316 673 2018 Antisense
TCAAAAATGTCTCCCATTTTCCCCT 534 629 2072 Antisense
CAAAAATCTCGTCCTTTTTCTCATC 466 191 2197 Antisense
TTGTTTCATGTTTCATTTTCCCCAC 373 707 2240 Antisense
TCTGCTTGTTTCATTTTTTCCACTG 574 609 2301 Antisense
Sequence Source GenBank