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[175736_at] guanine nucleotide-binding protein

Description g2443297 /REP_DB=GenBank Identifier /GB=AB003486.1 /PROTEIN_GB=BAA22401.1 /CHR=1 /FEA=Mapped Transcript /DEF=G protein a(s) subunit
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 02      4grp_highest_8_8 > 48      4grp_high_8_8 > 43      6grp_highest_nonorm > 11      6grp_total > 24      4grp_total > 45      6grp_highest_sub > De      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 951
1 2 3 4 range
A 1894.4
(3)
P 		1865.3
(2.8)
P 		1292.7
(-2.1)
P 		1181.5
(-3)
P 		713
B 2121.2
(3)
P 		1816.5
(0.7)
P 		1630.9
(-0.7)
P 		1330.1
(-3)
P 		791
C 1953.2
(2.3)
P 		2060.3
(3)
P 		1474.5
(-0.9)
P 		1170.3
(-3)
P 		890
avr 1989.6
(3) 		1914
(2.4) 		1466
(-1.1) 		1227.3
(-3) 		762

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2533
1 2 3 4 5 6 range
A 3074.9
(3)
P 		2065.8
(0.3)
P 		1745.4
(-0.6)
P 		834.1
(-3)
P 		1124.5
(-2.2)
P 		1112.9
(-2.3)
P 		2241
B 2827
(3)
P 		1946.3
(0.7)
P 		1550.5
(-0.4)
P 		1581.1
(-0.3)
P 		541.5
(-3)
P 		884
(-2.1)
P 		2286
C 1685.6
(1.4)
P 		1766
(1.8)
P 		1984.3
(3)
P 		1096.1
(-1.8)
P 		867.4
(-3)
P 		893.6
(-2.9)
P 		1117
avr 2529.2
(3) 		1926
(0.9) 		1760.1
(0.3) 		1170.4
(-1.8) 		844.5
(-3) 		963.5
(-2.6) 		1685
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 517
1 2 3 4 range
A 689.7
(3)
P 		404.9
(-0.3)
P 		337.9
(-1.1)
P 		172.9
(-3)
P 		517
B 676.4
(3)
P 		448.6
(-0.5)
P 		377.9
(-1.6)
P 		283.5
(-3)
P 		393
C 646.6
(3)
P 		592.3
(2.3)
P 		513.9
(1.2)
P 		197.3
(-3)
P 		449
avr 670.9
(3) 		481.9
(0.5) 		409.9
(-0.5) 		217.9
(-3) 		453

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 772
1 2 3 4 5 6 range
A 566.8
(1.1)
P 		734.7
(3)
P 		380.1
(-1.1)
P 		211.5
(-3)
P 		339.3
(-1.5)
P 		270.9
(-2.3)
P 		523
B 983.7
(3)
P 		647.9
(0.4)
P 		376.5
(-1.8)
P 		418.8
(-1.4)
P 		220
(-3)
P 		329.7
(-2.1)
P 		764
C 624.8
(3)
P 		538.9
(1.7)
P 		505
(1.2)
P 		220.4
(-3)
P 		280.7
(-2.1)
P 		299.2
(-1.8)
P 		404
avr 725.1
(3) 		640.5
(1.9) 		420.5
(-1.1) 		283.6
(-3) 		280
(-3) 		299.9
(-2.7) 		445
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175736_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19625
Sequence Type Exemplar sequence
Representative Public ID 2443297 NCBI
Target Description g2443297 /REP_DB=GenBank Identifier /GB=AB003486.1 /PROTEIN_GB=BAA22401.1 /CHR=1 /FEA=Mapped Transcript /DEF=G protein a(s) subunit
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058416(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058416 NCBI Caenorhabditis elegans G protein, Subunit Alpha family member (gsa-1) (gsa-1) mRNA, complete cds. 11/11 A 
R06A10.2.1 ENSEMBL cdna:known chromosome:CEL140:I:1068593:1075012:1 gene:R06A10.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1068592-1075026(+) 92.55 100.0
Public Domain and Genome References
Gene Title guanine nucleotide-binding protein
Gene Symbol gsa-1
Ensembl R06A10.2
Entrez Gene 171687 Entrez gene
SwissProt O18678 EMBL-EBI
WormBase CE21115 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1584931_AT GNAS complex locus cfa
CANINE_2:CFA.1247.1.S1_AT GNAS complex locus cfa
CANINE_2:CFAAFFX.18882.1.S1_S_AT GNAS complex locus cfa
DROSOPHILA_2:1639015_S_AT G protein s 60A dm
DROSGENOME1:154356_AT G protein s 60A dm
CHICKEN:GGAAFFX.22266.1.S1_S_AT GNAS complex locus gga
CHICKEN:GGAAFFX.22266.2.S1_AT GNAS complex locus gga
CHICKEN:GGAAFFX.22266.2.S1_S_AT GNAS complex locus gga
CHICKEN:GGA.10262.1.S1_AT GNAS complex locus gga
HG-U133_PLUS_2:200780_X_AT GNAS complex locus hs
HG-U133A_2:200780_X_AT GNAS complex locus hs
HG-U133A:200780_X_AT GNAS complex locus hs
HG-U133_PLUS_2:200981_X_AT GNAS complex locus hs
HG-U133A_2:200981_X_AT GNAS complex locus hs
HG-U133A:200981_X_AT GNAS complex locus hs
HG-U133_PLUS_2:217058_AT GNAS complex locus hs
HG-U133A_2:217058_AT GNAS complex locus hs
HG-U133A:217058_AT GNAS complex locus hs
HG-U95AV2:37450_R_AT GNAS complex locus hs
HG-U133_PLUS_2:214548_X_AT GNAS complex locus hs
HG-U133A_2:214548_X_AT GNAS complex locus hs
HG-U133A:214548_X_AT GNAS complex locus hs
HG-U133_PLUS_2:217673_X_AT GNAS complex locus hs
HG-U133A_2:217673_X_AT GNAS complex locus hs
HG-U133A:217673_X_AT GNAS complex locus hs
HG-U133_PLUS_2:211858_X_AT GNAS complex locus hs
HG-U133A:211858_X_AT GNAS complex locus hs
HG-U133A_2:211858_X_AT GNAS complex locus hs
HU35KSUBC:RC_W88587_AT GNAS complex locus hs
HUGENEFL:M21142_CDS2_S_AT GNAS complex locus hs
HG-U133_PLUS_2:217057_S_AT GNAS complex locus hs
HG-U133A_2:217057_S_AT GNAS complex locus hs
HG-FOCUS:217057_S_AT GNAS complex locus hs
HG-U133A:217057_S_AT GNAS complex locus hs
U133_X3P:G3552031_3P_A_AT GNAS complex locus hs
U133_X3P:G3552031_3P_S_AT GNAS complex locus hs
U133_X3P:HS.325202.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.273385.2.A1_3P_S_AT GNAS complex locus hs
U133_X3P:HS.273385.1.A1_3P_S_AT GNAS complex locus hs
U133_X3P:HS.113368.3.A1_3P_A_AT GNAS complex locus hs
HG-U133A_2:212273_X_AT GNAS complex locus hs
HG-U133_PLUS_2:212273_X_AT GNAS complex locus hs
HG-U133A:212273_X_AT GNAS complex locus hs
HG-U95AV2:31604_AT GNAS complex locus hs
HG-U95AV2:37448_S_AT GNAS complex locus hs
HG-U95AV2:37449_I_AT GNAS complex locus hs
HG-U95B:46156_AT GNAS complex locus hs
HG-U95C:63729_F_AT GNAS complex locus hs
HG-U95E:79959_R_AT GNAS complex locus hs
HG-U133A:214157_AT GNAS complex locus hs
HG-U133_PLUS_2:214157_AT GNAS complex locus hs
HG-U133A_2:214157_AT GNAS complex locus hs
HG-FOCUS:214157_AT GNAS complex locus hs
HG-U133_PLUS_2:228173_AT GNAS complex locus hs
HG-U133B:228173_AT GNAS complex locus hs
HG-U133_PLUS_2:229274_AT GNAS complex locus hs
HG-U133B:229274_AT GNAS complex locus hs
HG-U133_PLUS_2:235851_S_AT GNAS complex locus hs
HG-U133B:235851_S_AT GNAS complex locus hs
HG-U133_PLUS_2:239037_AT GNAS complex locus hs
HG-U133B:239037_AT GNAS complex locus hs
HG-U133_PLUS_2:242816_AT GNAS complex locus hs
HG-U133B:242816_AT GNAS complex locus hs
HG-U133_PLUS_2:242975_S_AT GNAS complex locus hs
HG-U133B:242975_S_AT GNAS complex locus hs
HG-U95B:45630_AT GNAS complex locus hs
HG-U95B:46055_AT GNAS complex locus hs
HG-U95B:46155_AT GNAS complex locus hs
HG-U95B:50967_AT GNAS complex locus hs
HG-U95D:81444_AT GNAS complex locus hs
HG-U95E:83906_AT GNAS complex locus hs
HG-U95D:90463_AT GNAS complex locus hs
HG-U95D:90465_G_AT GNAS complex locus hs
HU35KSUBA:AA062932_AT GNAS complex locus hs
HU35KSUBA:AA203742_AT GNAS complex locus hs
HU35KSUBA:D81936_AT GNAS complex locus hs
HU35KSUBA:H68018_S_AT GNAS complex locus hs
HU35KSUBC:RC_AA292703_AT GNAS complex locus hs
HU35KSUBA:RC_AA192339_AT GNAS complex locus hs
HU35KSUBC:RC_AA035219_AT GNAS complex locus hs
HU35KSUBC:RC_AA251879_AT GNAS complex locus hs
U133_X3P:HS.157307.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.159354.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.159354.1.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.38057.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.46853.0.A1_3P_AT GNAS complex locus hs
U133_X3P:HS.87928.0.A1_3P_AT GNAS complex locus hs
MOE430A:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1453413_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:92672_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:102082_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1443375_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430B:1443375_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1421740_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74AV2:93271_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1450186_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBA:M13964_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBA:C80321_RC_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.725.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.35032.0_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.24250.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.19335.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MU11KSUBB:MSA.8432.0_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74BV2:105048_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOE430A:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430A_2:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MOUSE430_2:1427789_S_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus mm
MG-U74CV2:167920_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOE430B:1444767_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOUSE430_2:1444767_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MG-U74CV2:129891_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOE430B:1443007_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MOUSE430_2:1443007_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU11KSUBB:MSA.17559.0_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC17254_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18591_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18592_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18592_I_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBA:TC18593_F_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC35899_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC38249_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC39144_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
MU19KSUBC:TC39145_AT GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, mRNA (cDNA clone IMAGE:4013293) mm
RG-U34A:AF093569MRNA#1_S_AT XLas protein rn
RN-U34:RC_AI237836_AT XLas protein rn
RG-U34A:RC_AI237836_AT XLas protein rn
RG-U34A:X84047CDS_AT XLas protein rn
RG-U34A:RC_AI237836_G_AT XLas protein rn
RAE230A:1369897_S_AT XLas protein rn
RAT230_2:1369897_S_AT XLas protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB96733 G protein, subunit alpha protein 1 [Caenorhabditis elegans] ref|NP_490817.3| G protein, Subunit Alpha family member (gsa-1) [Caenorhabditis elegans] gb|AAG32094.1| heterotrimeric G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22402.1| G protein alpha subunit [Caenorhabditis elegans] dbj|BAA22401.1| G protein a(s) subunit [Caenorhabditis elegans] 0.0
blast AAW02912 gsa-1 [Caenorhabditis briggsae] 0.0
blast CAE74357 Hypothetical protein CBG22078 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:175736_AT
gcgcgcatttcgattttgtttctagaaatttcaattgtccgactggccgatctcggtccc
taacacagcactcctattcctccgccaaacaaaaaaaaacttggaatcgtccatcggcca
cgaagctcaagccttttgtgatataatttgattgttttaagcccattctctcctaaaaaa
aaaacgcgcacaacgacccactgataagcaagcttgcctgacctacctaatcataacctt
ccccccccccccccccatcccccctgaaatgttttgtgttgccaaacaaagaagctctcg
cacagttttaatcatccgggtacaacgtggtccgcccgtttttcggacacttggcacctc
tcttcttcacgctttatcctgtttttattttttctctttcaaattttccgatcacaggct
ttatagcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGCGCATTTCGATTTTGTTTCTAG 416 287 1767 Antisense
ATTTCAATTGTCCGACTGGCCGATC 32 17 1794 Antisense
GGCCACGAAGCTCAAGCCTTTTGTG 441 543 1882 Antisense
TTGATTGTTTTAAGCCCATTCTCTC 371 705 1914 Antisense
CGCACAACGACCCACTGATAAGCAA 204 255 1953 Antisense
ATAAGCAAGCTTGCCTGACCTACCT 222 23 1970 Antisense
TGACCTACCTAATCATAACCTTCCC 535 569 1985 Antisense
CCATCCCCCCTGAAATGTTTTGTGT 556 271 2021 Antisense
GAAGCTCTCGCACAGTTTTAATCAT 283 343 2057 Antisense
ATCATCCGGGTACAACGTGGTCCGC 433 1 2077 Antisense
TTTTCCGATCACAGGCTTTATAGCG 22 675 2170 Antisense
Sequence Source GenBank