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[175719_at] matrix metalloproteinase

Description g3152405 /REP_DB=GenBank Identifier /GB=AB007817.1 /PROTEIN_GB=BAA28353.1 /CHR=3 /FEA=Mapped Transcript /DEF=matrix metalloproteinase
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 10      4grp_high_8_8 > 04      6grp_highest_nonorm > 80      6grp_total > 03      4grp_total > 06      6grp_highest_sub > 04      6grp_cgc > 50      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 132
1 2 3 4 range
A 150
(3)
P 		115.4
(-3)
P 		133.2
(0.1)
P 		115.3
(-3)
A 		35
B 179.3
(3)
P 		83.7
(-3)
P 		121.8
(-0.6)
P 		130.1
(-0.1)
M 		96
C 92.9
(-3)
P 		130.5
(-1.2)
P 		110.2
(-2.2)
P 		215.5
(3)
P 		123
avr 140.7
(1.2) 		109.9
(-3) 		121.7
(-1.4) 		153.6
(3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 220
1 2 3 4 5 6 range
A 275.6
(1.8)
P 		299.2
(2.5)
P 		154.2
(-1.7)
P 		318.2
(3)
P 		185.1
(-0.8)
P 		106.9
(-3)
P 		211
B 201.7
(1.4)
P 		237.5
(3)
P 		213.9
(1.9)
P 		237.5
(3)
P 		140.4
(-1.3)
P 		103.2
(-3)
P 		134
C 247.5
(0.8)
P 		205.9
(-0.4)
P 		264.7
(1.3)
P 		322.7
(3)
P 		173.8
(-1.4)
P 		119.2
(-3)
P 		204
avr 241.6
(1.3) 		247.5
(1.5) 		210.9
(0.3) 		292.8
(3) 		166.4
(-1.1) 		109.8
(-3) 		183
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 54.6
(3)
P 		25.1
(-1.7)
P 		34.8
(-0.2)
P 		16.9
(-3)
A 		38
B 57.2
(3)
P 		20.7
(-3)
P 		28.2
(-1.8)
P 		27.7
(-1.8)
M 		37
C 30.7
(-3)
P 		37.5
(2.3)
P 		38.4
(3)
P 		36.3
(1.4)
P 		8
avr 47.5
(3) 		27.8
(-2.8) 		33.8
(-1) 		27
(-3) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 80
1 2 3 4 5 6 range
A 50.8
(-1.1)
P 		106.4
(3)
P 		33.6
(-2.4)
P 		80.7
(1.1)
P 		55.9
(-0.8)
P 		26
(-3)
P 		80
B 70.2
(1.7)
P 		79.1
(3)
P 		51.9
(-1)
P 		62.9
(0.6)
P 		57.1
(-0.3)
P 		38.5
(-3)
P 		41
C 91.7
(3)
P 		62.8
(-0.3)
P 		67.4
(0.2)
P 		64.9
(-0.1)
P 		56.2
(-1.1)
P 		39.9
(-3)
P 		52
avr 70.9
(1.5) 		82.8
(3) 		51
(-1) 		69.5
(1.3) 		56.4
(-0.3) 		34.8
(-3) 		48
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175719_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19821
Sequence Type Exemplar sequence
Representative Public ID 3152405 NCBI
Target Description g3152405 /REP_DB=GenBank Identifier /GB=AB007817.1 /PROTEIN_GB=BAA28353.1 /CHR=3 /FEA=Mapped Transcript /DEF=matrix metalloproteinase
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171138(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171138 NCBI Caenorhabditis elegans Zinc MetalloProtease family member (zmp-1) (zmp-1) mRNA, complete cds. 11/11 None
SNAP00000018710 ENSEMBL cdna:SNAP chromosome:CEL140:III:5926975:5929243:-1 11/11 None
EGAP1.3 ENSEMBL cdna:known chromosome:CEL140:III:5926847:5932902:-1 gene:EGAP1.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000018714 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:5926845-5932901(-) 98.79 100.0
Public Domain and Genome References
Gene Title matrix metalloproteinase
Gene Symbol zmp-1
Ensembl EGAP1.3
Entrez Gene 175839 Entrez gene
SwissProt O61266 EMBL-EBI
WormBase CE30930 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.10823.1.S1_AT similar to matrix metalloproteinase 17 preproprotein cfa
CANINE_2:CFAAFFX.10840.1.S1_S_AT similar to matrix metalloproteinase 17 preproprotein cfa
CANINE_2:CFAAFFX.10857.1.S1_S_AT similar to matrix metalloproteinase 17 preproprotein cfa
CHICKEN:GGAAFFX.25498.1.S1_AT similar to matrix metalloproteinase 17; membrane-type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4 gga
CHICKEN:GGAAFFX.25498.4.S1_S_AT similar to matrix metalloproteinase 17; membrane-type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4 gga
HG-U133_PLUS_2:206234_S_AT matrix metallopeptidase 17 (membrane-inserted) hs
HG-U133A:206234_S_AT matrix metallopeptidase 17 (membrane-inserted) hs
HG-FOCUS:206234_S_AT matrix metallopeptidase 17 (membrane-inserted) hs
HG-U133A_2:206234_S_AT matrix metallopeptidase 17 (membrane-inserted) hs
HUGENEFL:X89576_AT matrix metallopeptidase 17 (membrane-inserted) hs
U133_X3P:G7706618_3P_A_AT matrix metallopeptidase 17 (membrane-inserted) hs
HG-U95AV2:35401_S_AT matrix metallopeptidase 17 (membrane-inserted) hs
HG-U95B:48641_AT Matrix metallopeptidase 17 (membrane-inserted) hs
HG-U95B:50653_AT Matrix metallopeptidase 17 (membrane-inserted) hs
MG-U74AV2:92461_AT matrix metallopeptidase 17 mm
MOE430A:1448598_AT matrix metallopeptidase 17 mm
MOUSE430A_2:1448598_AT matrix metallopeptidase 17 mm
MOUSE430_2:1448598_AT matrix metallopeptidase 17 mm
RG-U34B:RC_AI043728_AT matrix metalloproteinase 17 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5578 extracellular matrix (sensu Metazoa) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_741156 Zinc MetalloProtease family member (zmp-1) [Caenorhabditis elegans] gb|AAM48565.1| Zinc metalloprotease protein 1 [Caenorhabditis elegans] dbj|BAA28353.1| matrix metalloproteinase [Caenorhabditis elegans] 0.0
blast AAN33033 zinc metalloproteinase ZMP-1 [Caenorhabditis briggsae] 1.0E-131
blast CAE64366 Hypothetical protein CBG09053 [Caenorhabditis briggsae] 1.0E-127
blast AAN33033 zinc metalloproteinase ZMP-1 [Caenorhabditis briggsae] 1.0E-121
blast CAE64363 Hypothetical protein CBG09050 [Caenorhabditis briggsae] 9.0E-98
Protein Domains
Database ID Description E-Value
Pfam IPR001818 EMBL-EBI Peptidase M10A and M12B, matrixin and adamalysin 6.5E-20
Sequence
Target Sequence 
>C. ELEGANS:175719_AT
cactgttgggcacaatctttgggtttttgttggagaaatgatttatgtcatctatggaaa
tcacatggttcacgcacctcttcgactttcggatatcggaattaatgagaaatacgtgga
tttggcttatgagtggcattatttcaatccgcctgctgtatacatttggaaaggatctcg
atattggaaattagacgagaaaatgtatcatcgaagagttgatgaaaggtatccaaaaga
tactgatctgaattgggcgagagttccaaaaggagtacattctgccttcacttatgaaaa
agaaattcatcttctacgtggaaatcaagtttttcgaatgaattcatcccgatctgtatt
tgatattgctgatggatatccccaacctttacaatcttttttcggattctgccctcgcaa
tgagaagcttgttctgaattcttcttct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACTGTTGGGCACAATCTTTGGGTT 603 195 1119 Antisense
TGGAAATCACATGGTTCACGCACCT 18 549 1173 Antisense
CACCTCTTCGACTTTCGGATATCGG 595 201 1193 Antisense
AGTGGCATTATTTCAATCCGCCTGC 243 59 1250 Antisense
CAATCCGCCTGCTGTATACATTTGG 478 181 1263 Antisense
GTACATTCTGCCTTCACTTATGAAA 213 461 1393 Antisense
TCGAATGAATTCATCCCGATCTGTA 575 599 1452 Antisense
GATGGATATCCCCAACCTTTACAAT 367 407 1489 Antisense
ACAATCTTTTTTCGGATTCTGCCCT 63 115 1509 Antisense
ATTCTGCCCTCGCAATGAGAAGCTT 579 9 1524 Antisense
GAAGCTTGTTCTGAATTCTTCTTCT 111 343 1542 Antisense
Sequence Source GenBank