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[175688_at] importin alpha, nuclear transport factor

Description g2795932 /REP_DB=GenBank Identifier /GB=AF040997.1 /PROTEIN_GB=AAB97173.1 /CHR=5 /FEA=Mapped Transcript /DEF=importin alpha 3
Cluster 6grp_highest_10_10 > 88      6grp_high1_10_10 > 88      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 92      6grp_total > 98      4grp_total > 13      6grp_highest_sub > Da      6grp_cgc > 69      6grp_high1_sub > Da      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 186
1 2 3 4 range
A 141.3
(-1.5)
P 		123.4
(-3)
P 		136.3
(-1.9)
P 		194.6
(3)
P 		71
B 216.5
(0.8)
P 		129.6
(-2)
P 		100
(-3)
P 		286.3
(3)
P 		186
C 173
(1.2)
P 		172.6
(1.1)
P 		157.7
(-3)
P 		179.7
(3)
P 		22
avr 176.9
(0.1) 		141.9
(-2.3) 		131.3
(-3) 		220.2
(3) 		89

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 425
1 2 3 4 5 6 range
A 175.8
(-1.8)
P 		183.5
(-1.7)
P 		258.3
(0.1)
P 		126.6
(-3)
P 		381.1
(3)
P 		382.3
(3)
P 		256
B 159
(-2.6)
P 		163.9
(-2.5)
P 		137.9
(-3)
P 		226.6
(-1.4)
P 		334.4
(0.5)
P 		477
(3)
P 		339
C 190.2
(-2)
P 		125.9
(-2.9)
P 		120.7
(-3)
P 		190.8
(-2)
P 		400.7
(1)
P 		545.6
(3)
P 		425
avr 175
(-2.7) 		157.8
(-3) 		172.3
(-2.7) 		181.3
(-2.5) 		372.1
(1.1) 		468.3
(3) 		311
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 46
1 2 3 4 range
A 51.4
(3)
P 		26.8
(-3)
P 		35.6
(-0.9)
P 		28.5
(-2.6)
P 		25
B 69
(3)
P 		32
(-1.8)
P 		23.2
(-3)
P 		61
(2)
P 		46
C 57.3
(3)
P 		49.6
(1.3)
P 		54.9
(2.5)
P 		30.3
(-3)
P 		27
avr 59.2
(3) 		36.1
(-3) 		37.9
(-2.5) 		39.9
(-2) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 152
1 2 3 4 5 6 range
A 32.4
(-3)
P 		65.3
(-0.6)
P 		56.3
(-1.2)
P 		32.1
(-3)
P 		115
(3)
P 		93.1
(1.4)
P 		83
B 55.3
(-2.1)
P 		54.6
(-2.1)
P 		33.5
(-3)
P 		60
(-1.9)
P 		135.9
(1.3)
P 		177.9
(3)
P 		144
C 70.5
(-1.4)
P 		38.4
(-2.7)
P 		30.7
(-3)
P 		38.4
(-2.7)
P 		129.7
(0.9)
P 		182.6
(3)
P 		152
avr 52.7
(-2.3) 		52.8
(-2.3) 		40.2
(-3) 		43.5
(-2.8) 		126.9
(1.7) 		151.2
(3) 		111
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175688_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19938
Sequence Type Exemplar sequence
Representative Public ID 2795932 NCBI
Target Description g2795932 /REP_DB=GenBank Identifier /GB=AF040997.1 /PROTEIN_GB=AAB97173.1 /CHR=5 /FEA=Mapped Transcript /DEF=importin alpha 3
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073453(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073453 NCBI Caenorhabditis elegans IMportin Alpha family member (ima-1) (ima-1) mRNA, complete cds. 11/11 A 
T19B10.7.2 ENSEMBL cdna:known chromosome:CEL140:V:11242263:11244356:1 gene:T19B10.7 11/11 None
T19B10.7.1 ENSEMBL cdna:known chromosome:CEL140:V:11242293:11244368:1 gene:T19B10.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11242293-11244368(+) 100.0 100.0
Public Domain and Genome References
Gene Title importin alpha, nuclear transport factor
Gene Symbol ima-1
Ensembl T19B10.7
Entrez Gene 179555 Entrez gene
SwissProt Q22560 EMBL-EBI
WormBase CE06461 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6606 protein import into nucleus inferred from electronic annotation QuickGO AmiGO
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8565 protein transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98540 Hypothetical protein T19B10.7 [Caenorhabditis elegans] ref|NP_505854.1| IMportin Alpha family member (ima-1) [Caenorhabditis elegans] sp|Q22560|IMA1_CAEEL Importin alpha-1 subunit (Karyopherin alpha-1 subunit) 0.0
blast AAB97173 importin alpha 1 [Caenorhabditis elegans] pir||T42404 importin alpha 3 - Caenorhabditis elegans 0.0
blast CAE75198 Hypothetical protein CBG23145 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002652 EMBL-EBI Importin alpha-like protein, beta-binding region 1.7E-31
Sequence
Target Sequence 
>C. ELEGANS:175688_AT
cattctcattttaggaactagcataaatcatttatttatcattttaaagtagaaaacttt
caattagttcattctttttcttaccaaaattctaacatcgaatagtcattttctgtacac
tagatttccatgttcttagctgccaacgttatttgcaccaacatatttgatttgttgcga
gaccgtttgagtaaagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATTCTCATTTTAGGAACTAGCATA 106 217 1574 Antisense
TCAATTAGTTCATTCTTTTTCTTAC 49 635 1633 Antisense
TCATTCTTTTTCTTACCAAAATTCT 25 619 1642 Antisense
TTCTTACCAAAATTCTAACATCGAA 105 689 1651 Antisense
AACATCGAATAGTCATTTTCTGTAC 664 137 1667 Antisense
TTTTCTGTACACTAGATTTCCATGT 165 677 1682 Antisense
GATTTCCATGTTCTTAGCTGCCAAC 74 429 1696 Antisense
AGCTGCCAACGTTATTTGCACCAAC 448 81 1711 Antisense
ATTTGCACCAACATATTTGATTTGT 297 17 1724 Antisense
TATTTGATTTGTTGCGAGACCGTTT 30 659 1737 Antisense
GTTGCGAGACCGTTTGAGTAAAGAA 270 437 1747 Antisense
Sequence Source GenBank