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[175653_at] origin recognition complex, second largest subunit ORC2

Description g1113104 /REP_DB=GenBank Identifier /GB=U40270.1 /PROTEIN_GB=AAC46954.1 /CHR=2 /FEA=Mapped Transcript /DEF=ceOrc2p
Cluster 6grp_highest_10_10 > 97      6grp_high1_10_10 > 78      4grp_highest_8_8 > 36      4grp_high_8_8 > 56      6grp_highest_nonorm > 91      6grp_total > 69      4grp_total > 63      6grp_highest_sub > Cu      6grp_cgc > 39      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 168
1 2 3 4 range
A 179.2
(-3)
P 		235.1
(3)
P 		187.8
(-2.1)
P 		202.3
(-0.5)
P 		56
B 263.9
(3)
P 		96.4
(-3)
P 		161.4
(-0.7)
P 		186.2
(0.2)
P 		168
C 170.9
(-0.6)
P 		134.1
(-3)
P 		227.2
(3)
P 		150.6
(-1.9)
P 		93
avr 204.7
(3) 		155.2
(-3) 		192.1
(1.5) 		179.7
(-0) 		50

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 302
1 2 3 4 5 6 range
A 227.4
(-0.5)
P 		176.2
(-1.6)
P 		103.8
(-3)
P 		253.3
(-0)
P 		233.9
(-0.4)
P 		405.8
(3)
P 		302
B 204.4
(-1.4)
P 		210.4
(-1.2)
P 		140.1
(-3)
P 		156.6
(-2.6)
P 		274.2
(0.4)
P 		376.5
(3)
P 		236
C 247.5
(-0.2)
P 		129.6
(-3)
P 		199.5
(-1.3)
P 		256.8
(0)
P 		249.8
(-0.1)
P 		380.7
(3)
P 		251
avr 226.4
(-1) 		172.1
(-2.4) 		147.8
(-3) 		222.2
(-1.1) 		252.6
(-0.4) 		387.7
(3) 		240
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 65.2
(3)
P 		51
(0.6)
P 		49.1
(0.3)
P 		29.6
(-3)
P 		36
B 84.1
(3)
P 		23.8
(-3)
P 		37.4
(-1.6)
P 		39.7
(-1.4)
P 		60
C 56.6
(0.5)
P 		38.5
(-1.5)
P 		79.2
(3)
P 		25.4
(-3)
P 		54
avr 68.6
(3) 		37.8
(-2) 		55.2
(0.8) 		31.6
(-3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 118
1 2 3 4 5 6 range
A 41.9
(-1.5)
P 		62.6
(0.1)
P 		22.6
(-3)
P 		64.2
(0.3)
P 		70.6
(0.8)
P 		98.8
(3)
P 		76
B 71.1
(-0.9)
P 		70
(-1)
P 		34
(-3)
P 		41.5
(-2.6)
P 		111.4
(1.4)
P 		140.4
(3)
P 		106
C 91.7
(0.6)
P 		39.5
(-3)
P 		50.8
(-2.2)
P 		51.6
(-2.2)
P 		80.8
(-0.2)
P 		127.4
(3)
P 		88
avr 68.2
(-0.8) 		57.4
(-1.5) 		35.8
(-3) 		52.4
(-1.8) 		87.6
(0.6) 		122.2
(3) 		86
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175653_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19710
Sequence Type Exemplar sequence
Representative Public ID 1113104 NCBI
Target Description g1113104 /REP_DB=GenBank Identifier /GB=U40270.1 /PROTEIN_GB=AAC46954.1 /CHR=2 /FEA=Mapped Transcript /DEF=ceOrc2p
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063938(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063938 NCBI Caenorhabditis elegans ORC family member (orc-2) (orc-2) mRNA, complete cds. 11/11 A 
F59E10.1 ENSEMBL cdna:known chromosome:CEL140:II:10873842:10877768:1 gene:F59E10.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10873836-10877593(+) 100.0 100.0
Public Domain and Genome References
Gene Title origin recognition complex, second largest subunit ORC2
Gene Symbol orc-2
Ensembl F59E10.1
Entrez Gene 174676 Entrez gene
SwissProt Q21037 EMBL-EBI
WormBase CE11492 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17091_S_AT origin recognition complex subunit 2 (ORC2) at
ATH1-121501:267173_AT origin recognition complex subunit 2 (ORC2) at
CANINE:1604191_AT similar to origin recognition complex, subunit 2 cfa
CANINE:1591003_AT similar to origin recognition complex, subunit 2 cfa
CANINE_2:CFA.20287.1.S1_S_AT similar to origin recognition complex, subunit 2 cfa
CANINE_2:CFA.5361.1.A1_AT similar to origin recognition complex, subunit 2 cfa
DROSOPHILA_2:1635760_AT Origin recognition complex subunit 2 dm
DROSGENOME1:152530_AT Origin recognition complex subunit 2 dm
CHICKEN:GGAAFFX.12525.1.S1_S_AT origin recognition complex, subunit 2-like (yeast) gga
HU35KSUBC:RC_N66852_AT origin recognition complex, subunit 2-like (yeast) hs
HUGENEFL:U27459_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U133A:204853_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U133_PLUS_2:204853_AT origin recognition complex, subunit 2-like (yeast) hs
HG-FOCUS:204853_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U133A_2:204853_AT origin recognition complex, subunit 2-like (yeast) hs
U133_X3P:G5453829_3P_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U95AV2:39943_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U95B:45023_R_AT origin recognition complex, subunit 2-like (yeast) hs
HG-U95E:90865_AT Origin recognition complex, subunit 2-like (yeast) hs
MU11KSUBA:C80251_RC_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MU11KSUBA:U27457_S_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MG-U74AV2:160838_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOE430A:1418225_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430A_2:1418225_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430_2:1418225_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOE430A:1418226_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430A_2:1418226_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430_2:1418226_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOE430A:1418227_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430A_2:1418227_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430_2:1418227_AT origin recognition complex, subunit 2-like (S. cerevisiae) mm
MOUSE430_2:1443800_AT Origin recognition complex, subunit 2-like (S. cerevisiae), mRNA (cDNA clone MGC:18406 IMAGE:4234871) mm
MOE430B:1443800_AT Origin recognition complex, subunit 2-like (S. cerevisiae), mRNA (cDNA clone MGC:18406 IMAGE:4234871) mm
RG-U34C:RC_AI145141_AT Origin recognition complex, subunit 2-like (S. cerevisiae) (predicted) rn
RAE230A:1389141_AT Origin recognition complex, subunit 2-like (S. cerevisiae) (predicted) rn
RAT230_2:1389141_AT Origin recognition complex, subunit 2-like (S. cerevisiae) (predicted) rn
YEAST_2:1773725_AT Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6260 DNA replication inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
808 origin recognition complex inferred from electronic annotation QuickGO AmiGO
5634 nucleus inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA85415 Hypothetical protein F59E10.1 [Caenorhabditis elegans] ref|NP_496339.1| ORC family member (orc-2) [Caenorhabditis elegans] sp|Q21037|ORC2_CAEEL Origin recognition complex subunit 2 (CeOrc2) gb|AAC46954.1| ceOrc2p 0.0
blast CAE59591 Hypothetical protein CBG02998 [Caenorhabditis briggsae] 1.0E-165
blast AAF66068 origin recognition complex subunit 2 [Cricetulus griseus] 8.0E-28
Protein Domains
Database ID Description E-Value
Pfam IPR007220 EMBL-EBI Origin recognition complex subunit 2 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:175653_AT
aaagacgagtagctgctgctactgctggaggacctcaaaaatgaacacactctgcctcct
tttgactcaatgtatttaccttcaattgttttatttgttgactctgcgccccccgtccgt
ccgtcgatgcttcttcatcccatttttttttacttcaattgaaacctcaatcttcactta
ctctcatctgaacgctcatatttaaggcaataattttcattttcaaatatatcaattgaa
acctttatctaccgtaataccaattttgtgtaccttttcaaaaatctcatttccccctcg
gttttttcttcacgatttctcaattattttcagtttctcactatcagtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAGACGAGTAGCTGCTGCTACTGC 59 123 1299 Antisense
CTGCTACTGCTGGAGGACCTCAAAA 358 237 1314 Antisense
TCAAAAATGAACACACTCTGCCTCC 395 629 1333 Antisense
TCTGCCTCCTTTTGACTCAATGTAT 483 609 1349 Antisense
TGACTCAATGTATTTACCTTCAATT 344 571 1361 Antisense
TGAAACCTCAATCTTCACTTACTCT 661 569 1458 Antisense
ACTTACTCTCATCTGAACGCTCATA 434 103 1474 Antisense
TCAATTGAAACCTTTATCTACCGTA 629 631 1530 Antisense
TTATCTACCGTAATACCAATTTTGT 565 671 1543 Antisense
TTCTCAATTATTTTCAGTTTCTCAC 604 691 1615 Antisense
TATTTTCAGTTTCTCACTATCAGTT 113 663 1623 Antisense
Sequence Source GenBank