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[175643_s_at] TGF-beta-like growth factor

Description g3328181 /REP_DB=GenBank Identifier /GB=AF074395.1 /PROTEIN_GB=AAC26791.1 /CHR=5 /FEA=Mapped Transcript /DEF=CET-1
Cluster 6grp_highest_10_10 > 61      6grp_high1_10_10 > 17      4grp_highest_8_8 > 59      4grp_high_8_8 > 25      6grp_highest_nonorm > 80      6grp_total > 16      4grp_total > 38      6grp_highest_sub > De      6grp_cgc > 12      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 193
1 2 3 4 range
A 264.1
(3)
P 		199.2
(-1.1)
P 		170.1
(-3)
P 		193.1
(-1.5)
P 		94
B 321.8
(3)
P 		170.6
(-1.7)
P 		128.6
(-3)
P 		192.3
(-1)
P 		193
C 295.4
(3)
P 		157
(-3)
P 		159.1
(-2.9)
P 		167.5
(-2.5)
P 		138
avr 293.8
(3) 		175.6
(-2) 		152.6
(-3) 		184.3
(-1.7) 		141

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 410
1 2 3 4 5 6 range
A 490.8
(3)
P 		242.2
(-1.1)
P 		168.6
(-2.4)
P 		130.7
(-3)
P 		210.6
(-1.7)
P 		179.2
(-2.2)
P 		360
B 421
(3)
P 		321.1
(0.7)
P 		220.4
(-1.7)
P 		218.2
(-1.7)
P 		164.5
(-3)
P 		199.9
(-2.2)
P 		257
C 377.4
(3)
P 		297.9
(1.4)
P 		126.1
(-2.1)
P 		80.4
(-3)
P 		113.4
(-2.3)
P 		98.4
(-2.6)
P 		297
avr 429.7
(3) 		287.1
(0) 		171.7
(-2.4) 		143.1
(-3) 		162.8
(-2.6) 		159.2
(-2.7) 		287
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 74
1 2 3 4 range
A 96.2
(3)
P 		43.2
(-1.7)
P 		44.5
(-1.6)
P 		28.3
(-3)
P 		68
B 102.6
(3)
P 		42.1
(-2)
P 		29.8
(-3)
P 		41
(-2.1)
P 		73
C 97.8
(3)
P 		45.1
(-1.5)
P 		55.4
(-0.7)
P 		28.2
(-3)
P 		70
avr 98.9
(3) 		43.5
(-2) 		43.2
(-2) 		32.5
(-3) 		66

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 130
1 2 3 4 5 6 range
A 90.5
(3)
P 		86.1
(2.5)
P 		36.7
(-2.6)
P 		33.2
(-3)
P 		63.5
(0.2)
P 		43.6
(-1.9)
P 		57
B 146.5
(3)
P 		106.9
(0.4)
P 		53.5
(-3)
P 		57.8
(-2.7)
P 		66.8
(-2.1)
P 		74.5
(-1.6)
P 		93
C 139.9
(3)
P 		90.9
(0.6)
P 		32.1
(-2.2)
P 		16.2
(-3)
P 		36.7
(-2)
P 		32.9
(-2.2)
P 		124
avr 125.6
(3) 		94.6
(0.9) 		40.8
(-2.7) 		35.7
(-3) 		55.7
(-1.7) 		50.3
(-2) 		90
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175643_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19903
Sequence Type Exemplar sequence
Representative Public ID 3328181 NCBI
Target Description g3328181 /REP_DB=GenBank Identifier /GB=AF074395.1 /PROTEIN_GB=AAC26791.1 /CHR=5 /FEA=Mapped Transcript /DEF=CET-1
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072308(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072308 NCBI Caenorhabditis elegans DPP/BMP-Like family member (dbl-1) (dbl-1) mRNA, complete cds. 11/11 A 
T25F10.2.2 ENSEMBL cdna:known chromosome:CEL140:V:6760723:6763010:1 gene:T25F10.2 11/11 None
T25F10.2.1 ENSEMBL cdna:known chromosome:CEL140:V:6760729:6763003:1 gene:T25F10.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6760727-6763011(+) 100.0 100.0
Public Domain and Genome References
Gene Title TGF-beta-like growth factor
Gene Symbol dbl-1
Ensembl T25F10.2
Entrez Gene 179068 Entrez gene
SwissProt O02424 EMBL-EBI
WormBase CE26386 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604541_AT similar to Bone morphogenetic protein 5 precursor (BMP-5) cfa
CANINE_2:CFAAFFX.4373.1.S1_S_AT similar to Bone morphogenetic protein 5 precursor (BMP-5) cfa
CHICKEN:GGA.620.1.S1_AT bone morphogenetic protein 5 gga
HG-U95AV2:1831_AT bone morphogenetic protein 5 hs
HC-G110:1831_AT bone morphogenetic protein 5 hs
HG-U95AV2:200_AT bone morphogenetic protein 5 hs
HC-G110:200_AT bone morphogenetic protein 5 hs
HG-U133_PLUS_2:205431_S_AT bone morphogenetic protein 5 hs
HG-U133A:205431_S_AT bone morphogenetic protein 5 hs
HG-FOCUS:205431_S_AT bone morphogenetic protein 5 hs
HG-U133A_2:205431_S_AT bone morphogenetic protein 5 hs
HUGENEFL:S81957_AT bone morphogenetic protein 5 hs
HUGENEFL:M60314_AT bone morphogenetic protein 5 hs
U133_X3P:G10835090_3P_A_AT bone morphogenetic protein 5 hs
U133_X3P:HS.1104.0.S2_3P_AT bone morphogenetic protein 5 hs
HG-U133A_2:205430_AT bone morphogenetic protein 5 hs
HG-U133_PLUS_2:205430_AT bone morphogenetic protein 5 hs
HG-U133A:205430_AT bone morphogenetic protein 5 hs
HG-U133_PLUS_2:233606_AT Bone morphogenetic protein 5 hs
HG-U133B:233606_AT Bone morphogenetic protein 5 hs
U133_X3P:HS.296648.0.S1_3P_AT Bone morphogenetic protein 5 hs
HG-U95C:53804_AT Bone morphogenetic protein 5 hs
HU35KSUBC:RC_R23252_AT Bone morphogenetic protein 5 hs
MOE430A:1421283_AT bone morphogenetic protein 5 mm
MOUSE430A_2:1421283_AT bone morphogenetic protein 5 mm
MOUSE430_2:1421283_AT bone morphogenetic protein 5 mm
MU11KSUBB:MSA.1463.0_S_AT bone morphogenetic protein 5 mm
MG-U74AV2:99393_AT bone morphogenetic protein 5 mm
MG-U74BV2:163125_AT bone morphogenetic protein 5 mm
MOE430A:1421282_AT bone morphogenetic protein 5 mm
MOUSE430A_2:1421282_AT bone morphogenetic protein 5 mm
MOUSE430_2:1421282_AT bone morphogenetic protein 5 mm
MOE430B:1455851_AT bone morphogenetic protein 5 mm
MOUSE430_2:1455851_AT bone morphogenetic protein 5 mm
MU19KSUBC:TC38150_AT Bone morphogenetic protein 5 (Bmp5), mRNA mm
RG-U34B:RC_AA946142_AT bone morphogenetic protein 5 (predicted) rn
RAE230B:1382657_AT bone morphogenetic protein 5 (predicted) rn
RAT230_2:1382657_AT bone morphogenetic protein 5 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
40007 growth inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8083 growth factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB04986 Dpp/bmp-like protein 1 [Caenorhabditis elegans] ref|NP_504709.1| DPP/BMP-Like family member (dbl-1) [Caenorhabditis elegans] gb|AAC27729.1| decapentaplegic protein homolog [Caenorhabditis elegans] 0.0
blast AAC26791 CET-1 [Caenorhabditis elegans] 0.0
blast CAE71944 Hypothetical protein CBG19011 [Caenorhabditis briggsae] 1.0E-157
Protein Domains
Database ID Description E-Value
Pfam IPR001839 EMBL-EBI Transforming growth factor beta 1.5E-52
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_504709.1 1 20-42
T25F10.2.2 1 20-42
T25F10.2.1 1 20-42
Sequence
Target Sequence 
>C. ELEGANS:175643_S_AT
acattaccactttttgtcatctccttgtttttccctaccattcattttctttactaactc
cttattttttggtgcaatgtgtcacgggtcctcatttctcaccttcaaccgtttttcctc
ttgttattcttgtcttcgattcacattttccttttcttccccgatgtttgtccatgtttc
tgtgattccttcctaatgttccttttctcctattttttccaaaccaagagctcttatgaa
gacggacagtttcttttcttgttttctctaattctcttcttccaaaaaatctatctctct
ttttcttctcactctcatcatttttcactcgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACATTACCACTTTTTGTCATCTCCT 225 105 1293 Antisense
CCATTCATTTTCTTTACTAACTCCT 58 271 1330 Antisense
TACTAACTCCTTATTTTTTGGTGCA 168 609 1344 Antisense
TTGGTGCAATGTGTCACGGGTCCTC 519 707 1361 Antisense
TTCCTCTTGTTATTCTTGTCTTCGA 134 701 1407 Antisense
TGTCTTCGATTCACATTTTCCTTTT 374 559 1423 Antisense
TGTTTGTCCATGTTTCTGTGATTCC 361 561 1457 Antisense
TATTTTTTCCAAACCAAGAGCTCTT 397 661 1503 Antisense
TGAAGACGGACAGTTTCTTTTCTTG 605 571 1529 Antisense
TTCTCTAATTCTCTTCTTCCAAAAA 623 691 1556 Antisense
TCACTCTCATCATTTTTCACTCGAT 454 627 1601 Antisense
Sequence Source GenBank