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[175638_at] tyrosine-protein kinase

Description g6470294 /REP_DB=GenBank Identifier /GB=AF200199.1 /PROTEIN_GB=AAF13716.1 /CHR=X /FEA=Mapped Transcript /DEF=MES-1
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 93      4grp_high_8_8 > 03      6grp_highest_nonorm > 90      6grp_total > 95      4grp_total > 22      6grp_cgc > 77      6grp_high1_sub > 04      6grp_cgc_sub > 04_05_06      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 86
1 2 3 4 range
A 72.9
(-3)
P 		79.2
(-2.3)
P 		93.7
(-0.6)
P 		125.6
(3)
P 		53
B 120
(3)
P 		60.4
(-1.8)
P 		61.5
(-1.7)
P 		45.4
(-3)
A 		75
C 99
(1.4)
P 		71.4
(-0.6)
P 		39.3
(-3)
A 		120.8
(3)
P 		82
avr 97.3
(3) 		70.3
(-2) 		64.8
(-3) 		97.3
(3) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 103
1 2 3 4 5 6 range
A 108.9
(1.8)
P 		42.6
(-3)
P 		124.7
(3)
P 		100.5
(1.2)
P 		93
(0.7)
P 		92.9
(0.7)
P 		82
B 106.7
(-0.2)
P 		79.8
(-2.3)
P 		71.3
(-3)
P 		84.7
(-1.9)
P 		146
(3)
P 		107.7
(-0.1)
P 		75
C 99.6
(-1.8)
P 		107.8
(-0.8)
P 		90.6
(-3)
P 		137.2
(3)
P 		94.7
(-2.5)
P 		110.1
(-0.5)
P 		47
avr 105.1
(1.9) 		76.7
(-3) 		95.5
(0.3) 		107.5
(2.4) 		111.2
(3) 		103.6
(1.7) 		35
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 29
1 2 3 4 range
A 26.5
(3)
P 		17.2
(-3)
P 		24.5
(1.7)
P 		18.4
(-2.2)
P 		9
B 38.3
(3)
P 		14.9
(-1.9)
P 		14.3
(-2)
P 		9.7
(-3)
A 		29
C 32.8
(3)
P 		20.5
(-0.9)
P 		13.7
(-3)
A 		20.4
(-0.9)
P 		19
avr 32.5
(3) 		17.5
(-2.5) 		17.5
(-2.5) 		16.2
(-3) 		16

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 20.1
(-0.7)
P 		15.2
(-3)
P 		27.2
(2.6)
P 		25.5
(1.8)
P 		28
(3)
P 		22.6
(0.5)
P 		13
B 37.1
(-0.2)
P 		26.6
(-1.7)
P 		17.3
(-3)
P 		22.4
(-2.3)
P 		59.3
(3)
P 		40.2
(0.3)
P 		42
C 36.9
(3)
P 		32.9
(1.3)
P 		23.1
(-3)
P 		27.6
(-1)
P 		30.7
(0.3)
P 		36.8
(3)
P 		14
avr 31.4
(0.2) 		24.9
(-2.1) 		22.5
(-3) 		25.2
(-2) 		39.3
(3) 		33.2
(0.8) 		17
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175638_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19968
Sequence Type Exemplar sequence
Representative Public ID 6470294 NCBI
Target Description g6470294 /REP_DB=GenBank Identifier /GB=AF200199.1 /PROTEIN_GB=AAF13716.1 /CHR=X /FEA=Mapped Transcript /DEF=MES-1
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171780(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171780 NCBI Caenorhabditis elegans Maternal Effect Sterile family member (mes-1) (mes-1) mRNA, complete cds. 11/11 A 
F54F7.5 ENSEMBL cdna:known chromosome:CEL140:X:11857415:11862294:1 gene:F54F7.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:11857421-11862295(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Gene Symbol mes-1
Ensembl F54F7.5
Entrez Gene 181362 Entrez gene
SwissProt Q20792 EMBL-EBI
WormBase CE28237 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5887 integral to plasma membrane inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91758 Hypothetical protein F54F7.5 [Caenorhabditis elegans] ref|NP_741906.1| Maternal Effect Sterile family member (mes-1) [Caenorhabditis elegans] gb|AAF13716.1| MES-1 [Caenorhabditis elegans] 0.0
blast CAE69868 Hypothetical protein CBG16200 [Caenorhabditis briggsae] 0.0
blast CAA91529 Hypothetical protein B0198.3 [Caenorhabditis elegans] ref|NP_510015.2| B0198.3 [Caenorhabditis elegans] 0.0
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_741906.1 1 469-491
F54F7.5 1 469-491
Sequence
Target Sequence 
>C. ELEGANS:175638_AT
gtttagatgaatacaccccaaccattccctttgtaatcaataatacataaaatcattgga
tccagattattgttaataagttgataactaatcagttttcaccgtaacatttccaataaa
cccacattcagattactcaaccatccctataacagtcaccttttcccacgaattacccct
ccctccacccacattgttcttgtcgagtatatattgatatattcatttttttttaccaat
gatatcattatccatttttctcactcatttgtgtttgtatagtttatcatttttgttcca
ttcaaaacatatgatcttaaatgtgacttcgaaacttttctgatctcactctcaattttt
ttttgttgttcccaacctctagactatcctgtgaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTTAGATGAATACACCCCAACCAT 363 449 2908 Antisense
CCCAACCATTCCCTTTGTAATCAAT 207 257 2924 Antisense
GTAACATTTCCAATAAACCCACATT 159 461 3011 Antisense
AACCCACATTCAGATTACTCAACCA 508 145 3026 Antisense
TACTCAACCATCCCTATAACAGTCA 154 647 3041 Antisense
CACCCACATTGTTCTTGTCGAGTAT 301 201 3093 Antisense
TATCCATTTTTCTCACTCATTTGTG 669 657 3156 Antisense
TAGTTTATCATTTTTGTTCCATTCA 460 653 3187 Antisense
AACTTTTCTGATCTCACTCTCAATT 554 139 3240 Antisense
TTTTGTTGTTCCCAACCTCTAGACT 110 677 3268 Antisense
CCAACCTCTAGACTATCCTGTGAAT 84 277 3279 Antisense
Sequence Source GenBank