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[175604_at]

Description g1381137 /REP_DB=GenBank Identifier /GB=U58085.1 /PROTEIN_GB=AAC47122.1 /CHR=5 /FEA=Mapped Transcript /DEF=CUL-3
Cluster 6grp_high1_10_10 > 38      4grp_highest_8_8 > 54      4grp_high_8_8 > 10      6grp_total > 18      4grp_total > 22      6grp_cgc > 01      6grp_high1_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 106
1 2 3 4 range
A 157.9
(0.7)
P 		168
(1.5)
P 		113.9
(-3)
P 		185.7
(3)
P 		72
B 206
(3)
P 		117.6
(-3)
P 		140.9
(-1.4)
P 		145.9
(-1.1)
P 		88
C 178.2
(1.9)
P 		111.2
(-2.3)
P 		99.9
(-3)
P 		196.6
(3)
P 		97
avr 180.7
(3) 		132.3
(-1.6) 		118.2
(-3) 		176.1
(2.6) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 228
1 2 3 4 5 6 range
A 273.5
(3)
P 		82
(-2.6)
P 		68.1
(-3)
P 		109.6
(-1.8)
P 		106.9
(-1.9)
A 		104.7
(-1.9)
P 		205
B 173.1
(3)
P 		123.2
(0.7)
P 		45.4
(-3)
P 		102.8
(-0.3)
P 		73.9
(-1.7)
P 		128.7
(0.9)
P 		128
C 110.9
(2.9)
P 		98.6
(0.8)
P 		76.4
(-3)
P 		99.9
(1)
P 		83.1
(-1.8)
A 		111.3
(3)
P 		35
avr 185.8
(3) 		101.3
(-1.1) 		63.3
(-3) 		104.1
(-1) 		88
(-1.8) 		114.9
(-0.5) 		123
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 57.5
(3)
P 		36.5
(-1.2)
P 		29.8
(-2.5)
P 		27.2
(-3)
P 		30
B 65.7
(3)
P 		29
(-3)
P 		32.6
(-2.4)
P 		31.1
(-2.7)
P 		37
C 59
(3)
P 		32
(-3)
P 		34.8
(-2.4)
P 		33.2
(-2.7)
P 		27
avr 60.7
(3) 		32.5
(-2.6) 		32.4
(-2.6) 		30.5
(-3) 		30

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 50.4
(3)
P 		29.2
(-0.6)
P 		14.8
(-3)
P 		27.8
(-0.8)
P 		32.2
(-0.1)
A 		25.5
(-1.2)
P 		36
B 60.2
(3)
P 		41
(0.7)
P 		11
(-3)
P 		27.2
(-1)
P 		30
(-0.7)
P 		48
(1.5)
P 		49
C 41.1
(3)
P 		30.1
(-0)
P 		19.4
(-3)
P 		20.1
(-2.8)
P 		26.9
(-0.9)
A 		37.3
(1.9)
P 		22
avr 50.6
(3) 		33.4
(0.1) 		15.1
(-3) 		25
(-1.3) 		29.7
(-0.5) 		36.9
(0.7) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175604_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19945
Sequence Type Exemplar sequence
Representative Public ID 1381137 NCBI
Target Description g1381137 /REP_DB=GenBank Identifier /GB=U58085.1 /PROTEIN_GB=AAC47122.1 /CHR=5 /FEA=Mapped Transcript /DEF=CUL-3
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070750(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070750 NCBI Caenorhabditis elegans CULlin family member (cul-3) (cul-3) mRNA, complete cds. 11/11 A 
Y108G3AL.1.1 ENSEMBL cdna:known chromosome:CEL140:V:177408:184867:1 gene:Y108G3AL.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Y108G3AL.1.2 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:177405-184868(+) 98.96 100.0
Public Domain and Genome References
Gene Title
Gene Symbol cul-3
Ensembl Y108G3AL.1
Entrez Gene 178547 Entrez gene
SwissProt Q17391 EMBL-EBI
WormBase CE27593 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:263685_AT cullin, putative at
ATGENOME1:17771_AT cullin, putative at
CANINE:1589793_S_AT similar to Cullin-3 (CUL-3) cfa
CANINE_2:CFA.657.1.A1_S_AT similar to Cullin-3 (CUL-3) cfa
CANINE_2:CFAAFFX.22384.1.S1_S_AT similar to Cullin-3 (CUL-3) cfa
DROSOPHILA_2:1624970_S_AT guftagu dm
DROSGENOME1:153701_AT guftagu dm
CHICKEN:GGA.4769.1.S1_S_AT cullin 3 gga
CHICKEN:GGAAFFX.26407.1.S1_AT cullin 3 gga
CHICKEN:GGAAFFX.26407.3.S1_S_AT cullin 3 gga
HG-U133A:201372_S_AT cullin 3 hs
HG-U133_PLUS_2:201372_S_AT cullin 3 hs
HG-U133A_2:201372_S_AT cullin 3 hs
HG-U133A:201370_S_AT cullin 3 hs
HG-U133_PLUS_2:201370_S_AT cullin 3 hs
HG-U133A_2:201370_S_AT cullin 3 hs
HG-U133A:201371_S_AT cullin 3 hs
HG-U133_PLUS_2:201371_S_AT cullin 3 hs
HG-U133A_2:201371_S_AT cullin 3 hs
HG-FOCUS:201371_S_AT cullin 3 hs
HU35KSUBB:RC_F13623_S_AT cullin 3 hs
HU35KSUBD:RC_H98621_S_AT cullin 3 hs
HUGENEFL:U58089_AT cullin 3 hs
U133_X3P:G4503164_3P_A_AT cullin 3 hs
U133_X3P:G3139078_3P_A_AT cullin 3 hs
U133_X3P:HS.78946.0.A2_3P_A_AT cullin 3 hs
HG-U95AV2:37702_AT cullin 3 hs
HG-U133_PLUS_2:237376_AT Cullin 3 hs
HG-U133B:237376_AT Cullin 3 hs
HG-U133_PLUS_2:237985_AT Cullin 3 hs
HG-U133B:237985_AT Cullin 3 hs
HG-U133_PLUS_2:241016_AT Cullin 3 hs
HG-U133B:241016_AT Cullin 3 hs
HG-U133_PLUS_2:241855_S_AT Cullin 3 hs
HG-U133B:241855_S_AT Cullin 3 hs
HG-U133_PLUS_2:242362_AT Cullin 3 hs
HG-U133B:242362_AT Cullin 3 hs
HG-U95E:69872_AT Cullin 3 hs
HG-U95D:81154_AT Cullin 3 hs
HG-U95D:83329_AT Cullin 3 hs
HG-U95E:83938_AT Cullin 3 hs
HG-U95E:84623_AT Cullin 3 hs
HG-U95D:90657_AT Cullin 3 hs
U133_X3P:HS.155690.0.A1_3P_AT Cullin 3 hs
U133_X3P:HS.155690.1.A1_3P_AT Cullin 3 hs
U133_X3P:HS.159577.0.A1_3P_AT Cullin 3 hs
U133_X3P:HS.171110.0.A1_3P_AT Cullin 3 hs
U133_X3P:HS.201853.0.A1_3P_AT Cullin 3 hs
MG-U74AV2:92797_AT cullin 3 mm
MG-U74BV2:111920_AT cullin 3 mm
MOE430A:1422795_AT cullin 3 mm
MOUSE430A_2:1422795_AT cullin 3 mm
MOUSE430_2:1422795_AT cullin 3 mm
MOE430A:1422794_AT cullin 3 mm
MOUSE430A_2:1422794_AT cullin 3 mm
MOUSE430_2:1422794_AT cullin 3 mm
MOE430A:1450756_S_AT cullin 3 mm
MOUSE430A_2:1450756_S_AT cullin 3 mm
MOUSE430_2:1450756_S_AT cullin 3 mm
MG-U74BV2:108296_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MG-U74BV2:115360_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MOUSE430_2:1434717_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MOE430B:1434717_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MOE430B:1434718_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MOUSE430_2:1434718_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
MU19KSUBC:TC40586_AT Cullin 3, mRNA (cDNA clone MGC:28933 IMAGE:3981170) mm
RG-U34B:RC_AA901222_AT cullin 3 (predicted) rn
RG-U34C:RC_AI072520_AT cullin 3 (predicted) rn
RAE230A:1399132_AT cullin 3 (predicted) rn
RAT230_2:1399132_AT cullin 3 (predicted) rn
RAE230B:1393343_AT cullin 3 (predicted) rn
RAT230_2:1393343_AT cullin 3 (predicted) rn
RAE230A:1376241_AT Cullin 3 (predicted) rn
RAT230_2:1376241_AT Cullin 3 (predicted) rn
RAE230B:1396400_AT Cullin 3 (predicted) rn
RAT230_2:1396400_AT Cullin 3 (predicted) rn
RG-U34C:RC_AA858761_AT Cullin 3 (predicted) rn
RG-U34C:RC_AI105022_AT Cullin 3 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7049 cell cycle inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK72067 Cullin protein 3 [Caenorhabditis elegans] ref|NP_503151.1| CULlin family member (cul-3) [Caenorhabditis elegans] sp|Q17391|CUL3_CAEEL Cullin-3 0.0
blast AAC47122 CUL-3 0.0
blast CAE62355 Hypothetical protein CBG06434 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
scop a.4.5.SCF ubiquitin ligase complex WHB domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; SCF ubiquitin ligase complex WHB domain 1.00000002374223E-32
Pfam IPR001373 EMBL-EBI Cullin 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:175604_AT
cattgcctagggtcgattttttcgtttggtttccaatgattttcactctcatctgctctc
catttacttttgctatattctcttaaaacacagcaacaacgatttgttcataaatacgta
atttctgtggttatttttacatttaaatttatttatttattccttctctctttttttctc
actcgattcttggacctgatgttgccttgaacatttgtatgtagatgggtcttttttttt
cattatttcccccaaatcatttcaaaattattttattattttcattatatcatctcgtca
aatttgctccctatccagatagtatccacccctgaaagtttttgtccccaccaagggtgt
cattgaataatcgatttcaaaaaagttttgggatgaattgaaaaacgaaaaatgttcgat
ttttagaaaaaatcgaaaaaaaccgacacccttggtcccctttttatgtgtgtga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATTGCCTAGGGTCGATTTTTTCGT 289 217 2404 Antisense
CAATGATTTTCACTCTCATCTGCTC 307 183 2437 Antisense
TCTGCTCTCCATTTACTTTTGCTAT 482 609 2455 Antisense
CATTTACTTTTGCTATATTCTCTTA 320 215 2464 Antisense
TATTCTCTTAAAACACAGCAACAAC 518 663 2479 Antisense
TTTTTTTCTCACTCGATTCTTGGAC 314 675 2574 Antisense
GATTCTTGGACCTGATGTTGCCTTG 219 431 2588 Antisense
TGTAGATGGGTCTTTTTTTTTCATT 161 561 2623 Antisense
TCATTATTTCCCCCAAATCATTTCA 293 619 2643 Antisense
TATCATCTCGTCAAATTTGCTCCCT 474 659 2691 Antisense
CTTGGTCCCCTTTTTATGTGTGTGA 97 219 2854 Antisense
Sequence Source GenBank