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[175567_at] RAS-related protein

Description CE6051 /REP_DB=TREMBL Accession /GB=T01605 /CHR=1 /FEA=Genomic Cluster /DEF=wEST02326 Early embryo, Stratagene (cat. no. 937007) Caenorhabditis elegans cDNA clone CEEST15 similar to ras-related protein ora-3, mRNA sequence.
Cluster 6grp_highest_10_10 > 90      6grp_high1_10_10 > 09      4grp_highest_8_8 > 22      4grp_high_8_8 > 07      6grp_highest_nonorm > 57      6grp_total > 92      4grp_total > 01      6grp_cgc > 98      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2012
1 2 3 4 range
A 2541.9
(-1)
P 		2448.2
(-3)
P 		2654.4
(1.4)
P 		2729.6
(3)
P 		281
B 2517.1
(-1.1)
P 		2055.3
(-3)
P 		2330.8
(-1.9)
P 		3513.6
(3)
P 		1458
C 1923.3
(-3)
P 		2018.1
(-2.7)
P 		2181.8
(-2.2)
P 		3935.7
(3)
P 		2012
avr 2327.4
(-2.2) 		2173.9
(-3) 		2389
(-1.9) 		3393
(3) 		1219

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1462
1 2 3 4 5 6 range
A 1972.2
(-2.8)
P 		2441.8
(0.6)
P 		1944.6
(-3)
P 		2773.1
(3)
P 		2464.2
(0.8)
P 		2183.2
(-1.3)
P 		829
B 2512.7
(2.2)
P 		2625.4
(3)
P 		1815
(-3)
P 		2123.9
(-0.7)
P 		2456.7
(1.8)
P 		1814.6
(-3)
P 		811
C 2687.7
(0.9)
P 		2479.9
(0)
P 		2300.6
(-0.7)
P 		1746.4
(-3)
P 		3208.3
(3)
P 		1910
(-2.3)
P 		1462
avr 2390.9
(0.4) 		2515.7
(1.4) 		2020.1
(-2.6) 		2214.5
(-1) 		2709.7
(3) 		1969.3
(-3) 		740
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 526
1 2 3 4 range
A 925.5
(3)
P 		531.4
(-1.5)
P 		693.9
(0.4)
P 		399.6
(-3)
P 		526
B 802.7
(3)
P 		507.6
(-3)
P 		540.1
(-2.3)
P 		748.8
(1.9)
P 		295
C 636.7
(-1.1)
P 		580.2
(-3)
P 		760.4
(3)
P 		663.6
(-0.2)
P 		180
avr 788.3
(3) 		539.7
(-3) 		664.8
(0) 		604
(-1.4) 		249

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 687
1 2 3 4 5 6 range
A 363.6
(-3)
P 		868.4
(3)
P 		423.5
(-2.3)
P 		703.3
(1)
P 		743.6
(1.5)
P 		531.5
(-1)
P 		505
B 874.3
(1.7)
P 		873.9
(1.7)
P 		440.7
(-3)
P 		562.5
(-1.7)
P 		998.1
(3)
P 		676.6
(-0.5)
P 		557
C 996.2
(2.6)
P 		756.7
(0.5)
P 		585.5
(-1)
P 		351.2
(-3)
P 		1038.2
(3)
P 		639.4
(-0.5)
P 		687
avr 744.7
(0.5) 		833
(1.7) 		483.2
(-3) 		539
(-2.2) 		926.6
(3) 		615.8
(-1.2) 		443
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175567_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20431
Sequence Type Exemplar sequence
Representative Public ID CE6051 NCBI
Target Description CE6051 /REP_DB=TREMBL Accession /GB=T01605 /CHR=1 /FEA=Genomic Cluster /DEF=wEST02326 Early embryo, Stratagene (cat. no. 937007) Caenorhabditis elegans cDNA clone CEEST15 similar to ras-related protein ora-3, mRNA sequence.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058274(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058274 NCBI Caenorhabditis elegans RAB family member (rab-11.1) (rab-11.1) mRNA, complete cds. 11/11 None
F53G12.1 ENSEMBL cdna:known chromosome:CEL140:I:108682:110057:-1 gene:F53G12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:108705-109185(-) 100.0 100.0
Public Domain and Genome References
Gene Title RAS-related protein
Gene Symbol rab-11.1
Ensembl F53G12.1
Entrez Gene 171601 Entrez gene
SwissProt O01803 EMBL-EBI
WormBase CE11006 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264669_AT Ras-related GTP-binding protein, putative at
ATGENOME1:16600_S_AT Ras-related GTP-binding protein, putative at
CANINE:1596423_S_AT RAB11A, member RAS oncogene family cfa
CANINE_2:CFA.3814.1.S1_S_AT RAB11A, member RAS oncogene family cfa
DROSOPHILA_2:1626902_A_AT Rab-protein 11 dm
DROSGENOME1:143843_AT Rab-protein 11 dm
CHICKEN:GGAAFFX.12505.1.S1_AT RAB11A, member RAS oncogene family gga
CHICKEN:GGAAFFX.12505.1.S1_S_AT RAB11A, member RAS oncogene family gga
HG-U133_PLUS_2:200863_S_AT RAB11A, member RAS oncogene family hs
HG-U133A:200863_S_AT RAB11A, member RAS oncogene family hs
HG-U133A_2:200863_S_AT RAB11A, member RAS oncogene family hs
HG-FOCUS:200863_S_AT RAB11A, member RAS oncogene family hs
HG-U133_PLUS_2:200864_S_AT RAB11A, member RAS oncogene family hs
HG-U133A:200864_S_AT RAB11A, member RAS oncogene family hs
HG-U133A_2:200864_S_AT RAB11A, member RAS oncogene family hs
HUGENEFL:AF000231_AT RAB11A, member RAS oncogene family hs
U133_X3P:G4758983_3P_A_AT RAB11A, member RAS oncogene family hs
U133_X3P:HS.75618.0.S1_3P_A_AT RAB11A, member RAS oncogene family hs
HG-U95AV2:36660_AT RAB11A, member RAS oncogene family hs
HU35KSUBB:RC_N41061_AT RAB11A, member RAS oncogene family hs
HU35KSUBB:RC_Z39194_AT RAB11A, member RAS oncogene family hs
HU35KSUBB:RC_R07646_AT RAB11A, member RAS oncogene family hs
HU35KSUBB:RC_H29231_AT RAB11A, member RAS oncogene family hs
U133_X3P:HS.27384.0.A1_3P_AT RAB11A, member RAS oncogene family hs
HG-U133_PLUS_2:234998_AT RAB11A, member RAS oncogene family hs
HG-U133B:234998_AT RAB11A, member RAS oncogene family hs
HG-U95C:61624_AT RAB11A, member RAS oncogene family hs
MOE430A:1434549_AT RAB11a, member RAS oncogene family mm
MOUSE430A_2:1434549_AT RAB11a, member RAS oncogene family mm
MOUSE430_2:1434549_AT RAB11a, member RAS oncogene family mm
MU11KSUBA:D50500_F_AT RAB11a, member RAS oncogene family mm
MU11KSUBA:AA530037_AT RAB11a, member RAS oncogene family mm
MU11KSUBB:MSA.19548.0_S_AT RAB11a, member RAS oncogene family mm
MG-U74AV2:92854_AT RAB11a, member RAS oncogene family mm
MG-U74AV2:96238_AT RAB11a, member RAS oncogene family mm
MG-U74CV2:167286_AT RAB11a, member RAS oncogene family mm
MOE430A:1449256_A_AT RAB11a, member RAS oncogene family mm
MOUSE430A_2:1449256_A_AT RAB11a, member RAS oncogene family mm
MOUSE430_2:1449256_A_AT RAB11a, member RAS oncogene family mm
MU19KSUBA:TC15090_S_AT RAB11a, member RAS oncogene family, mRNA (cDNA clone MGC:6317 IMAGE:2811973) mm
MU19KSUBB:TC34918_AT RAB11a, member RAS oncogene family, mRNA (cDNA clone MGC:6317 IMAGE:2811973) mm
RG-U34A:E03859CDS_S_AT RAB11a, member RAS oncogene family rn
RG-U34A:M75153_AT RAB11a, member RAS oncogene family rn
RG-U34A:M75153_G_AT RAB11a, member RAS oncogene family rn
RG-U34C:RC_AI236487_AT RAB11a, member RAS oncogene family rn
RG-U34C:RC_AI235973_AT RAB11a, member RAS oncogene family rn
RAE230A:1374069_AT RAB11a, member RAS oncogene family rn
RAT230_2:1374069_AT RAB11a, member RAS oncogene family rn
RAE230A:1398814_AT RAB11a, member RAS oncogene family rn
RAT230_2:1398814_AT RAB11a, member RAS oncogene family rn
YEAST_2:1774779_AT GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
160 two-component signal transduction system (phosphorelay) inferred from electronic annotation QuickGO AmiGO
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB54158 Rab family protein 11.1 [Caenorhabditis elegans] ref|NP_490675.1| RAB family member (rab-11.1) [Caenorhabditis elegans] 1.0E-117
blast CAE60313 Hypothetical protein CBG03904 [Caenorhabditis briggsae] 1.0E-113
blast AAP48704 rab11-2 [Limulus polyphemus] 2.0E-93
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 2.5E-99
Sequence
Target Sequence 
>C. ELEGANS:175567_AT
caaatgattcgctcttaacatccgcgagttttatcgaattcttgcaagcactgcgtttgc
aagtcttcaccgttttggtgtgtagtatttgtaactttctttcagatttatttgtaattg
cctccatccccaccccttccccctcccccccctccgaacctatacattcgtccctttttc
ttcagaagattgtgatctgagttgagtggtgctgctttcttaccatttatccgactcaag
attgtatgccaacttcagcgacgtattttgaatattttttcttcacccttattcaatatt
attctggcccacccccacccaatgtgtatattacctaaactattttggttattcgtaatg
tgtgtctcttgtagaactcgataccgagaaaccctcgccaagaaagcaacgaagacatat
gcacattgtttttaatcgagtttta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAATGATTCGCTCTTAACATCCGC 165 193 16 Antisense
CGCTCTTAACATCCGCGAGTTTTAT 497 251 25 Antisense
ACATCCGCGAGTTTTATCGAATTCT 107 107 33 Antisense
ATCGAATTCTTGCAAGCACTGCGTT 404 37 48 Antisense
AGCACTGCGTTTGCAAGTCTTCACC 103 77 62 Antisense
TTTGCAAGTCTTCACCGTTTTGGTG 336 667 71 Antisense
GTCTTCACCGTTTTGGTGTGTAGTA 76 469 78 Antisense
GTATTTGTAACTTTCTTTCAGATTT 295 453 100 Antisense
GATTTATTTGTAATTGCCTCCATCC 264 429 120 Antisense
GAAGACATATGCACATTGTTTTTAA 18 341 426 Antisense
GCACATTGTTTTTAATCGAGTTTTA 150 315 436 Antisense
Sequence Source Affymetrix Proprietary Database