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[175541_at] potassium channel protein

Description AU116367_rc /REP_DB=TREMBL Accession /GB=AU116367 /CHR=X /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk743h11 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 52      6grp_high1_10_10 > 26      4grp_high_8_8 > 50      6grp_highest_nonorm > 10      6grp_total > 35      4grp_total > 61      6grp_highest_sub > 01_02      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1950
1 2 3 4 range
A 2034
(3)
P 		1501.6
(1.4)
P 		1233
(0.5)
P 		88.6
(-3)
A 		1945
B 1411.9
(3)
P 		1406
(3)
P 		1368.8
(2.8)
P 		84
(-3)
A 		1328
C 1799.4
(3)
P 		1513.8
(1.9)
P 		1391.4
(1.5)
P 		195
(-3)
P 		1604
avr 1748.4
(3) 		1473.8
(2) 		1331.1
(1.5) 		122.5
(-3) 		1626

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1395
1 2 3 4 5 6 range
A 1858.3
(3)
P 		1701
(2.1)
P 		1458.2
(0.7)
P 		796.4
(-3)
P 		904.1
(-2.4)
P 		997.5
(-1.9)
P 		1062
B 2006.1
(3)
P 		1640.5
(1.2)
P 		1054.7
(-1.8)
P 		970.1
(-2.2)
P 		810.6
(-3)
P 		1291.7
(-0.6)
P 		1196
C 1375.9
(0.6)
P 		1901.5
(3)
P 		1182.8
(-0.3)
P 		955.2
(-1.4)
P 		611.3
(-3)
P 		1112.3
(-0.7)
P 		1290
avr 1746.8
(3) 		1747.7
(3) 		1231.9
(-0.2) 		907.2
(-2.2) 		775.3
(-3) 		1133.8
(-0.8) 		972
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 728
1 2 3 4 range
A 740.6
(3)
P 		326
(-0.4)
P 		322.3
(-0.4)
P 		13
(-3)
A 		728
B 450.2
(3)
P 		347.2
(1.6)
P 		317.2
(1.2)
P 		17.9
(-3)
A 		432
C 595.6
(3)
P 		435.2
(1.3)
P 		485
(1.8)
P 		32.9
(-3)
P 		563
avr 595.5
(3) 		369.5
(0.6) 		374.8
(0.7) 		21.3
(-3) 		574

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 506
1 2 3 4 5 6 range
A 342.6
(-0.9)
P 		605
(3)
P 		317.6
(-1.3)
P 		202
(-3)
P 		272.8
(-1.9)
P 		242.9
(-2.4)
P 		403
B 698
(3)
P 		546.1
(0.9)
P 		256.1
(-3)
P 		256.9
(-3)
P 		329.3
(-2)
P 		481.7
(0.1)
P 		442
C 510
(1.9)
P 		580.2
(3)
P 		301.1
(-1.3)
P 		192.1
(-3)
P 		197.8
(-2.9)
P 		372.4
(-0.2)
P 		388
avr 516.9
(2) 		577.1
(3) 		291.6
(-1.8) 		217
(-3) 		266.6
(-2.2) 		365.7
(-0.5) 		360
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175541_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22166
Sequence Type Exemplar sequence
Representative Public ID AU116367 NCBI
Target Description AU116367_rc /REP_DB=TREMBL Accession /GB=AU116367 /CHR=X /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk743h11 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077115(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077115 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-18) (twk-18) mRNA, complete cds. 11/11 A 
C24A3.6.1 ENSEMBL cdna:known chromosome:CEL140:X:8988072:8991896:1 gene:C24A3.6 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:8991547-8991833(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol twk-18
Ensembl C24A3.6
Entrez Gene 181139 Entrez gene
SwissProt Q18120 EMBL-EBI
WormBase CE24811 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from direct assay QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
15271 outward rectifier potassium channel activity inferred from direct assay QuickGO AmiGO
15271 outward rectifier potassium channel activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA81456 Twik family of potassium channels protein 18 [Caenorhabditis elegans] ref|NP_509516.1| TWiK family of potassium channels family member (twk-18) [Caenorhabditis elegans] sp|Q18120|TWK18_CAEEL TWiK family of potassium channels protein 18 gb|AAC32861.1| potassium channel subunit n2P18 [Caenorhabditis elegans] 0.0
blast CAE57311 Hypothetical protein CBG00233 [Caenorhabditis briggsae] 0.0
blast T15584 hypothetical protein C24A3.6 - Caenorhabditis elegans 1.0E-166
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509516.1 6 21-43,112-134,147-169,226-248,253-275,279-301
C24A3.6.1 6 21-43,112-134,147-169,226-248,253-275,279-301
Sequence
Target Sequence 
>C. ELEGANS:175541_AT
gcatgtcatttcttatccactacacgttttcccgcgtccaattaaaaaaaagaaagaaaa
aatctcaaaaaaaaataccagggccttgttctaatagctagttttcgattagttacaggc
atacataaatcaacttaaactttctcgtctgcgagaaaaagctgcttcacgaataccgcg
tgccacaaaaccgacaccgactaaaactcaacgaagatttcataaatcttagttctaatt
gtttcctcaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCATGTCATTTCTTATCCACTACAC 234 311 18 Antisense
CATTTCTTATCCACTACACGTTTTC 328 215 24 Antisense
ATACCAGGGCCTTGTTCTAATAGCT 376 11 92 Antisense
GGCCTTGTTCTAATAGCTAGTTTTC 683 543 99 Antisense
GTTTTCGATTAGTTACAGGCATACA 192 449 118 Antisense
TACAGGCATACATAAATCAACTTAA 77 637 131 Antisense
TCAACTTAAACTTTCTCGTCTGCGA 275 629 147 Antisense
AAAAGCTGCTTCACGAATACCGCGT 280 129 174 Antisense
CACGAATACCGCGTGCCACAAAACC 103 199 185 Antisense
CGACACCGACTAAAACTCAACGAAG 457 249 209 Antisense
TCTTAGTTCTAATTGTTTCCTCACA 102 617 244 Antisense
Sequence Source Affymetrix Proprietary Database