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[175474_at] fork-head domain-type transcription factors

Description AV185494_rc /REP_DB=TREMBL Accession /GB=AV185494 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk679a12 : 3prime end, single read.
Cluster 6grp_total > 08      4grp_total > 60      6grp_cgc > 11      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 95
1 2 3 4 range
A 72.8
(1.7)
P 		52.7
(0.4)
A 		91.1
(3)
P 		3.9
(-3)
A 		87
B 65.8
(-1.9)
P 		67.9
(-0.8)
A 		63.8
(-3)
A 		75.2
(3)
A 		11
C 81.1
(-1.6)
P 		97.6
(2.7)
P 		75.9
(-3)
A 		98.6
(3)
A 		23
avr 73.2
(1.7) 		72.7
(1.6) 		76.9
(3) 		59.2
(-3) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 89
1 2 3 4 5 6 range
A 111.4
(3)
A 		67.2
(-1.4)
M 		53
(-2.8)
A 		56.6
(-2.5)
A 		55.4
(-2.6)
A 		51.5
(-3)
A 		60
B 88.2
(3)
P 		51.1
(-1.2)
A 		35.6
(-3)
A 		49.1
(-1.5)
A 		48.1
(-1.6)
A 		54.4
(-0.9)
A 		53
C 89.3
(3)
P 		46.5
(-0.8)
A 		61.7
(0.5)
A 		69.7
(1.2)
A 		22.3
(-3)
A 		57.4
(0.1)
A 		67
avr 96.3
(3) 		54.9
(-1.6) 		50.1
(-2.1) 		58.5
(-1.2) 		41.9
(-3) 		54.4
(-1.6) 		54
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 26.5
(3)
P 		11.4
(-0.5)
A 		23.8
(2.4)
P 		0.6
(-3)
A 		26
B 21
(3)
P 		16.8
(-1.1)
A 		14.8
(-3)
A 		16
(-1.8)
A 		6
C 26.9
(2.4)
P 		28.1
(3)
P 		26.5
(2.2)
A 		16.6
(-3)
A 		12
avr 24.8
(3) 		18.8
(0.4) 		21.7
(1.6) 		11.1
(-3) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 20.5
(1.3)
A 		23.9
(3)
M 		11.6
(-3)
A 		14.4
(-1.6)
A 		16.7
(-0.5)
A 		12.5
(-2.6)
A 		12
B 30.7
(3)
P 		17
(-0.7)
A 		8.6
(-3)
A 		13
(-1.8)
A 		19.5
(-0)
A 		20.3
(0.2)
A 		22
C 33.1
(3)
P 		14.2
(-1.4)
A 		15.7
(-1)
A 		14
(-1.4)
A 		7.2
(-3)
A 		19.2
(-0.2)
A 		26
avr 28.1
(3) 		18.4
(-0.6) 		12
(-3) 		13.8
(-2.3) 		14.5
(-2.1) 		17.3
(-1) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175474_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20392
Sequence Type Exemplar sequence
Representative Public ID AV185494 NCBI
Target Description AV185494_rc /REP_DB=TREMBL Accession /GB=AV185494 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk679a12 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059425(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059425 NCBI Caenorhabditis elegans LEThal family member (let-381) (let-381) mRNA, complete cds. 11/11 A 
SNAP00000041716 ENSEMBL cdna:SNAP chromosome:CEL140:I:6328560:6329745:-1 11/11 None
GENEFINDER00000041722 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6328560:6334828:-1 11/11 None
F26B1.7 ENSEMBL cdna:known chromosome:CEL140:I:6328560:6332118:-1 gene:F26B1.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
F26B1.2a 11/11 Negative Strand Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6328500-6328825(-) 100.0 100.0
Public Domain and Genome References
Gene Title fork-head domain-type transcription factors
Gene Symbol let-381
Ensembl F26B1.7
Entrez Gene 172331 Entrez gene
SwissProt P91278 EMBL-EBI
WormBase CE28006 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 1.0E-178
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 1.0E-176
blast CAE67163 Hypothetical protein CBG12589 [Caenorhabditis briggsae] 1.0E-109
blast NP_491826 LEThal family member (let-381) [Caenorhabditis elegans] gb|AAB37792.2| Lethal protein 381 [Caenorhabditis elegans] 7.0E-88
blast CAE67163 Hypothetical protein CBG12589 [Caenorhabditis briggsae] 7.0E-46
blast CAF98088 unnamed protein product [Tetraodon nigroviridis] 1.0E-30
Protein Domains
Database ID Description E-Value
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 8.00000014402008E-35
scop a.4.5.Forkhead DNA-binding domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; Forkhead DNA-binding domain 1.0000000467011E-34
Pfam IPR001766 EMBL-EBI Fork head transcription factor 1.7E-40
Pfam IPR001766 EMBL-EBI Fork head transcription factor 1.7E-40
Sequence
Target Sequence 
>C. ELEGANS:175474_AT
aatgcaatgggcttcaccaacatatgactggccgtattatgcaactccacacattggatt
atgttcatcggattttcctggaatctcgccttctccaactgttactcctcaggtttcccc
atatttttatccaccagcaatcacaacggcctcgagcttcatggatgattggcgttttgg
agtttcatctgctgctgttggcgcctatgacagctccgcgtcatttttggccgcagagac
gact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATGCAATGGGCTTCACCAACATAT 516 165 19 Antisense
GACTGGCCGTATTATGCAACTCCAC 543 375 44 Antisense
GATTATGTTCATCGGATTTTCCTGG 571 429 75 Antisense
TCGGATTTTCCTGGAATCTCGCCTT 45 607 86 Antisense
TCAGGTTTCCCCATATTTTTATCCA 354 615 127 Antisense
TTTTTATCCACCAGCAATCACAACG 135 675 142 Antisense
GGCCTCGAGCTTCATGGATGATTGG 556 543 166 Antisense
CGTTTTGGAGTTTCATCTGCTGCTG 370 247 191 Antisense
TGCTGCTGTTGGCGCCTATGACAGC 244 581 208 Antisense
CTATGACAGCTCCGCGTCATTTTTG 695 223 223 Antisense
GTCATTTTTGGCCGCAGAGACGACT 23 469 238 Antisense
Sequence Source Affymetrix Proprietary Database