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[175406_at]

Description AV183882_rc /REP_DB=TREMBL Accession /GB=AV183882 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk657d3 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 81      6grp_high1_10_10 > 29      4grp_highest_8_8 > 49      4grp_high_8_8 > 49      6grp_highest_nonorm > 40      6grp_total > 28      4grp_total > 54      6grp_highest_sub > Cu      6grp_cgc > 03      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 603
1 2 3 4 range
A 918.5
(3)
P 		592.9
(-0.5)
P 		634.1
(-0.1)
P 		359.1
(-3)
P 		559
B 927.5
(3)
P 		575.7
(-0.6)
P 		535
(-1.1)
P 		347.2
(-3)
P 		580
C 945.9
(3)
P 		606.4
(-0.4)
P 		587.1
(-0.6)
P 		342.5
(-3)
P 		603
avr 930.6
(3) 		591.7
(-0.5) 		585.4
(-0.6) 		349.6
(-3) 		581

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 651
1 2 3 4 5 6 range
A 976.9
(3)
P 		817.3
(1.3)
P 		400.8
(-3)
P 		592.1
(-1)
P 		725.1
(0.4)
P 		699
(0.1)
P 		576
B 851.1
(3)
P 		755.9
(1.6)
P 		441.2
(-3)
P 		630.1
(-0.2)
P 		697.2
(0.7)
P 		582.8
(-0.9)
P 		410
C 1051.8
(3)
P 		693.6
(-0.3)
P 		513
(-2)
P 		409.5
(-3)
P 		652.6
(-0.7)
P 		507.1
(-2.1)
P 		642
avr 959.9
(3) 		755.6
(0.6) 		451.7
(-3) 		543.9
(-1.9) 		691.6
(-0.2) 		596.3
(-1.3) 		508
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 282
1 2 3 4 range
A 334.4
(3)
P 		128.7
(-1.4)
P 		165.8
(-0.6)
P 		52.6
(-3)
P 		282
B 295.8
(3)
P 		142.2
(-1.2)
P 		124
(-1.6)
P 		74
(-3)
P 		222
C 313.1
(3)
P 		174.3
(-0.3)
P 		204.6
(0.5)
P 		57.7
(-3)
P 		255
avr 314.4
(3) 		148.4
(-0.9) 		164.8
(-0.5) 		61.4
(-3) 		253

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 308
1 2 3 4 5 6 range
A 180.1
(-0.3)
P 		290.7
(3)
P 		87.3
(-3)
P 		150.2
(-1.1)
P 		218.8
(0.9)
P 		170.2
(-0.6)
P 		203
B 296.1
(3)
P 		251.6
(1.6)
P 		107.1
(-3)
P 		166.9
(-1.1)
P 		283.3
(2.6)
P 		217.3
(0.5)
P 		189
C 389.9
(3)
P 		211.6
(-0.5)
P 		130.6
(-2.1)
P 		82.4
(-3)
P 		211.2
(-0.5)
P 		169.8
(-1.3)
P 		308
avr 288.7
(3) 		251.3
(1.8) 		108.3
(-3) 		133.2
(-2.2) 		237.8
(1.3) 		185.8
(-0.4) 		180
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175406_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20430
Sequence Type Exemplar sequence
Representative Public ID AV183882 NCBI
Target Description AV183882_rc /REP_DB=TREMBL Accession /GB=AV183882 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk657d3 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026607(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026607 NCBI Caenorhabditis elegans C-terminal Src Kinase family member (csk-1) (csk-1) mRNA, complete cds. 11/11 None
Y48G1C.2.1 ENSEMBL cdna:known chromosome:CEL140:I:71858:81071:1 gene:Y48G1C.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Y48G1C.2.2 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:80709-80998(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol csk-1
Ensembl Y48G1C.2
Entrez Gene 266817 Entrez gene
SwissProt Q9BL77 EMBL-EBI
WormBase CE34405 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1602451_AT similar to c-src tyrosine kinase cfa
CANINE_2:CFA.14304.1.A1_AT similar to c-src tyrosine kinase cfa
CANINE_2:CFAAFFX.27473.1.S1_AT similar to c-src tyrosine kinase cfa
CANINE_2:CFAAFFX.27473.1.S1_S_AT similar to c-src tyrosine kinase cfa
DROSOPHILA_2:1624464_S_AT C-terminal Src kinase dm
DROSGENOME1:141422_AT C-terminal Src kinase dm
CHICKEN:GGA.2691.1.S1_AT c-src tyrosine kinase gga
HG-U133A:202329_AT c-src tyrosine kinase hs
HG-U133_PLUS_2:202329_AT c-src tyrosine kinase hs
HG-FOCUS:202329_AT c-src tyrosine kinase hs
HG-U133A_2:202329_AT c-src tyrosine kinase hs
HG-U95AV2:1768_S_AT c-src tyrosine kinase hs
HC-G110:1768_S_AT c-src tyrosine kinase hs
HUGENEFL:X59932_S_AT c-src tyrosine kinase hs
U133_X3P:G4758077_3P_AT c-src tyrosine kinase hs
MU11KSUBA:U05247_F_AT c-src tyrosine kinase mm
MU11KSUBA:AA275044_S_AT c-src tyrosine kinase mm
MU11KSUBB:MSA.258.0_F_AT c-src tyrosine kinase mm
MG-U74AV2:94046_AT c-src tyrosine kinase mm
MOE430A:1423518_AT c-src tyrosine kinase mm
MOUSE430A_2:1423518_AT c-src tyrosine kinase mm
MOUSE430_2:1423518_AT c-src tyrosine kinase mm
MOE430B:1439744_AT C-src tyrosine kinase, mRNA (cDNA clone MGC:25873 IMAGE:4206879) mm
MOUSE430_2:1439744_AT C-src tyrosine kinase, mRNA (cDNA clone MGC:25873 IMAGE:4206879) mm
MG-U74AV2:162504_AT C-src tyrosine kinase, mRNA (cDNA clone MGC:25873 IMAGE:4206879) mm
RG-U34A:X58631CDS_AT c-src tyrosine kinase (predicted) rn
RG-U34C:RC_AI177363_S_AT c-src tyrosine kinase (predicted) rn
RG-U34C:RC_AI178605_AT c-src tyrosine kinase (predicted) rn
RAE230A:1371592_AT c-src tyrosine kinase (predicted) rn
RAT230_2:1371592_AT c-src tyrosine kinase (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5942 phosphoinositide 3-kinase complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
16303 phosphatidylinositol 3-kinase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_001021778 C-terminal Src Kinase family member (csk-1) [Caenorhabditis elegans] gb|AAK29898.3| C-terminal src kinase protein 1 [Caenorhabditis elegans] dbj|BAC76831.1| CSK-1 [Caenorhabditis elegans] 0.0
blast CAE60320 Hypothetical protein CBG03911 [Caenorhabditis briggsae] 0.0
blast XP_871877 PREDICTED: similar to c-src tyrosine kinase isoform 2 [Bos taurus] 1.0E-107
Protein Families
Method ID Description E-Value
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 1.0E-36
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-80
Sequence
Target Sequence 
>C. ELEGANS:175406_AT
aaacatcaagaaacttctattcgaaagaattttttaaaattgtattttccgaaataattt
tctctgttgggtctcaccacgaaaatcgtcatgcacctttaaatttccttgcccacacct
ctccgaacggccgatacccaatctacggtttcttcaattttcctctgcatttttcatcga
tt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACATCAAGAAACTTCTATTCGAA 549 125 47 Antisense
GTATTTTCCGAAATAATTTTCTCTG 485 453 88 Antisense
ATAATTTTCTCTGTTGGGTCTCACC 564 23 100 Antisense
GGTCTCACCACGAAAATCGTCATGC 239 503 116 Antisense
CCACGAAAATCGTCATGCACCTTTA 18 275 123 Antisense
ATCGTCATGCACCTTTAAATTTCCT 526 35 131 Antisense
TGCACCTTTAAATTTCCTTGCCCAC 257 575 138 Antisense
CGATACCCAATCTACGGTTTCTTCA 390 249 178 Antisense
CTACGGTTTCTTCAATTTTCCTCTG 375 223 189 Antisense
TCAATTTTCCTCTGCATTTTTCATC 6 635 200 Antisense
TTTTCCTCTGCATTTTTCATCGATT 460 677 204 Antisense
Sequence Source Affymetrix Proprietary Database