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[175368_at] ADP/ATP carrier protein

Description AV185613_rc /REP_DB=TREMBL Accession /GB=AV185613 /CHR=X /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk681a5 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 42      6grp_high1_10_10 > 25      4grp_highest_8_8 > 53      4grp_high_8_8 > 08      6grp_highest_nonorm > 71      6grp_total > 02      4grp_total > 23      6grp_highest_sub > 02      6grp_high1_sub > 01_02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 211
1 2 3 4 range
A 441.9
(3)
P 		267.2
(-3)
P 		337.3
(-0.6)
P 		427.6
(2.5)
P 		175
B 477.8
(3)
P 		353.4
(-1.5)
P 		310.9
(-3)
P 		394.2
(-0)
P 		167
C 457
(3)
P 		345.9
(-3)
P 		368.5
(-1.8)
P 		422.1
(1.1)
P 		111
avr 458.9
(3) 		322.2
(-3) 		338.9
(-2.3) 		414.6
(1.1) 		137

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 354
1 2 3 4 5 6 range
A 529.6
(3)
P 		456.5
(1.3)
P 		356.9
(-1)
P 		334.1
(-1.5)
P 		270
(-3)
P 		290
(-2.5)
P 		260
B 398
(2.1)
P 		437.9
(3)
P 		175.5
(-3)
P 		355.5
(1.1)
P 		266.3
(-0.9)
P 		312.6
(0.1)
P 		262
C 310.7
(-1.2)
P 		480.3
(3)
P 		344.3
(-0.4)
P 		365.4
(0.1)
P 		286.3
(-1.8)
P 		239.2
(-3)
P 		241
avr 412.8
(1.5) 		458.2
(3) 		292.2
(-2.4) 		351.7
(-0.5) 		274.2
(-3) 		280.6
(-2.8) 		184
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 160.9
(3)
P 		58
(-3)
P 		88.2
(-1.2)
P 		62.6
(-2.7)
P 		103
B 152.4
(3)
P 		87.3
(-1.9)
P 		72
(-3)
P 		84
(-2.1)
P 		80
C 151.3
(3)
P 		99.4
(-0.9)
P 		128.4
(1.3)
P 		71.2
(-3)
P 		80
avr 154.9
(3) 		81.6
(-2.3) 		96.2
(-1.3) 		72.6
(-3) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 120
1 2 3 4 5 6 range
A 97.6
(-1.2)
P 		162.4
(3)
P 		77.7
(-2.5)
P 		84.7
(-2.1)
P 		81.5
(-2.3)
P 		70.6
(-3)
P 		92
B 138.5
(2.6)
P 		145.7
(3)
P 		42.6
(-3)
P 		94.2
(0)
P 		108.2
(0.8)
P 		116.6
(1.3)
P 		103
C 115.1
(0.4)
P 		146.6
(3)
P 		87.6
(-1.8)
P 		73.5
(-3)
P 		92.6
(-1.4)
P 		80.1
(-2.5)
P 		73
avr 117.1
(0.5) 		151.6
(3) 		69.3
(-3) 		84.1
(-1.9) 		94.1
(-1.2) 		89.1
(-1.6) 		82
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175368_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22144
Sequence Type Exemplar sequence
Representative Public ID AV185613 NCBI
Target Description AV185613_rc /REP_DB=TREMBL Accession /GB=AV185613 /CHR=X /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk681a5 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077680(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077680 NCBI Caenorhabditis elegans F17E5.2 (F17E5.2) mRNA, complete cds. 11/11 None
F17E5.2 ENSEMBL cdna:known chromosome:CEL140:X:12394186:12399411:1 gene:F17E5.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12399099-12399379(+) 100.0 100.0
Public Domain and Genome References
Gene Title ADP/ATP carrier protein
Ensembl F17E5.2
Entrez Gene 181399 Entrez gene
SwissProt Q19529 EMBL-EBI
WormBase CE37355 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250623_AT mitochondrial substrate carrier family protein at
CANINE_2:CFAAFFX.30755.1.S1_S_AT similar to solute carrier family 25, member 25 isoform a cfa
DROSOPHILA_2:1629806_A_AT dm
DROSGENOME1:152957_AT dm
DROSGENOME1:148658_AT dm
CHICKEN:GGAAFFX.26398.2.S1_S_AT similar to mitochondrial Ca2+-dependent solute carrier; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 gga
MG-U74AV2:98569_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MG-U74BV2:162537_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430A:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430A_2:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430B:1454284_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1454284_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430B:1447856_X_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1447856_X_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MU19KSUBC:TC36285_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25, mRNA (cDNA clone MGC:47196 IMAGE:5368306) mm
MU19KSUBC:TC37114_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25, mRNA (cDNA clone MGC:47196 IMAGE:5368306) mm
RG-U34C:RC_AA817759_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
RAE230A:1371754_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
RAT230_2:1371754_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
YEAST_2:1769358_AT Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5743 mitochondrial inner membrane inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90761 Hypothetical protein F17E5.2 [Caenorhabditis elegans] ref|NP_510081.3| F17E5.2 [Caenorhabditis elegans] sp|Q19529|CMC3_CAEEL Probable calcium-binding mitochondrial carrier F17E5.2 0.0
blast T21074 hypothetical protein F17E5.2 - Caenorhabditis elegans 0.0
blast CAE57255 Hypothetical protein CBG00135 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 3.3E-35
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.3E-34
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.1E-27
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 1.2E-4
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 3.3E-5
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 0.088
Sequence
Target Sequence 
>C. ELEGANS:175368_AT
gttattttttcaattgcatagttatttatctatttattagattttctgtgttttttttca
ctctttaattgtcattatttcattgcctttttctgtattttttgaaaccctggtgtcatt
ctcaatgtttcacctaccttttggcacttccactgtggtagtgcaacagctcttggtcag
tacagtagtccccgtaccattttattttcaaacagttactctcttctgtctctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTATTTTTTCAATTGCATAGTTAT 11 449 18 Antisense
TATTTCATTGCCTTTTTCTGTATTT 187 663 93 Antisense
TCTGTATTTTTTGAAACCCTGGTGT 400 605 109 Antisense
GAAACCCTGGTGTCATTCTCAATGT 238 359 121 Antisense
GTGTCATTCTCAATGTTTCACCTAC 91 487 130 Antisense
TCAATGTTTCACCTACCTTTTGGCA 192 633 139 Antisense
CTTTTGGCACTTCCACTGTGGTAGT 21 223 155 Antisense
TGTGGTAGTGCAACAGCTCTTGGTC 239 555 171 Antisense
GTGCAACAGCTCTTGGTCAGTACAG 171 481 178 Antisense
TCTTGGTCAGTACAGTAGTCCCCGT 651 611 188 Antisense
AAACAGTTACTCTCTTCTGTCTCTT 72 127 227 Antisense
Sequence Source Affymetrix Proprietary Database