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[175249_s_at]

Description AU114985_rc /REP_DB=TREMBL Accession /GB=AU114985 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk724d9 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 52      6grp_high1_10_10 > 35      4grp_highest_8_8 > 33      4grp_high_8_8 > 58      6grp_highest_nonorm > 41      6grp_total > 26      4grp_total > 61      6grp_highest_sub > 01_02      6grp_cgc > 04      6grp_high1_sub > 02      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1124
1 2 3 4 range
A 1544.4
(3)
P 		1159.3
(0.4)
P 		1450.6
(2.4)
P 		665.6
(-3)
P 		879
B 1141.9
(3)
P 		1090
(2.5)
P 		979.9
(1.5)
P 		494
(-3)
P 		648
C 1338.8
(1)
P 		1241.4
(0.4)
P 		1618
(3)
P 		763.1
(-3)
P 		855
avr 1341.7
(2.9) 		1163.6
(1.4) 		1349.5
(3) 		640.9
(-3) 		709

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 609
1 2 3 4 5 6 range
A 889
(1.2)
P 		1060.4
(3)
P 		740
(-0.4)
P 		490.6
(-3)
P 		733.7
(-0.4)
P 		776
(0)
P 		570
B 1045.1
(3)
P 		946.5
(2)
P 		451.3
(-3)
P 		638.1
(-1.1)
P 		668.8
(-0.8)
P 		999.6
(2.5)
P 		594
C 821.4
(0.9)
P 		973.2
(3)
P 		782.3
(0.3)
P 		545.2
(-3)
P 		629.8
(-1.8)
P 		591.5
(-2.4)
P 		428
avr 918.5
(2) 		993.4
(3) 		657.9
(-1.6) 		558
(-3) 		677.4
(-1.4) 		789
(0.2) 		435
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 467
1 2 3 4 range
A 562.3
(3)
P 		251.6
(-1)
P 		379.2
(0.6)
P 		97.4
(-3)
P 		465
B 364.1
(3)
P 		269.2
(0.8)
P 		227.1
(-0.2)
P 		105.3
(-3)
P 		259
C 443.2
(1.3)
P 		356.9
(0.1)
P 		563.9
(3)
P 		128.7
(-3)
P 		435
avr 456.5
(3) 		292.6
(0.2) 		390.1
(1.8) 		110.5
(-3) 		346

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 268
1 2 3 4 5 6 range
A 163.9
(-2.1)
P 		377.1
(3)
P 		161.2
(-2.1)
P 		124.4
(-3)
P 		221.4
(-0.7)
P 		188.9
(-1.5)
P 		253
B 363.6
(2.8)
P 		315.1
(1.7)
P 		109.6
(-3)
P 		169
(-1.6)
P 		271.7
(0.7)
P 		372.7
(3)
P 		263
C 304.5
(3)
P 		296.9
(2.8)
P 		199.1
(-0.2)
P 		109.6
(-3)
P 		203.8
(-0.1)
P 		198
(-0.3)
P 		195
avr 277.3
(1.4) 		329.7
(3) 		156.6
(-2.3) 		134.3
(-3) 		232.3
(0) 		253.2
(0.7) 		195
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175249_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20223
Sequence Type Exemplar sequence
Representative Public ID AU114985 NCBI
Target Description AU114985_rc /REP_DB=TREMBL Accession /GB=AU114985 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk724d9 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060237(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060237 NCBI Caenorhabditis elegans Eukaryotic Initiation Factor family member (eif-3.C) (eif-3.C) mRNA, complete cds. 11/11 None
T23D8.4.1 ENSEMBL cdna:known chromosome:CEL140:I:9984547:9987783:-1 gene:T23D8.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9984495-9984894(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol eif-3.C
Ensembl T23D8.4
Entrez Gene 172858 Entrez gene
SwissProt O02328 EMBL-EBI
WormBase CE18958 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1583133_AT similar to eukaryotic translation initiation factor 3, subunit 8, 110kDa cfa
CANINE_2:CFA.11708.1.A1_AT similar to eukaryotic translation initiation factor 3, subunit 8, 110kDa cfa
CANINE_2:CFAAFFX.26234.1.S1_S_AT similar to eukaryotic translation initiation factor 3, subunit 8, 110kDa cfa
DROSOPHILA_2:1637193_AT dm
DROSGENOME1:147388_AT dm
HG-U133_PLUS_2:210949_S_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A:210949_S_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-FOCUS:210949_S_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A_2:210949_S_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133_PLUS_2:200647_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A:200647_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A_2:200647_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U95AV2:34841_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HU35KSUBC:RC_AA062652_S_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HUGENEFL:U46025_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
U133_X3P:G5579457_3P_A_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
U133_X3P:G12653522_3P_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
U133_X3P:G12653522_3P_A_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
U133_X3P:HS.192425.0.A1_3P_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A_2:215230_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133_PLUS_2:215230_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133A:215230_X_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133_PLUS_2:236700_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U133B:236700_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U95E:79411_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
HG-U95D:89988_AT Eukaryotic translation initiation factor 3, subunit 8, 110kDa hs
MOE430A:1415858_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430A_2:1415858_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430_2:1415858_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOE430A:1415859_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430_2:1415859_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430A_2:1415859_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOE430A:1456374_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430A_2:1456374_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430_2:1456374_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MU11KSUBA:U67328_S_AT eukaryotic translation initiation factor 3, subunit 8 mm
MU11KSUBB:MSA.14407.0_S_AT eukaryotic translation initiation factor 3, subunit 8 mm
MG-U74AV2:94837_AT eukaryotic translation initiation factor 3, subunit 8 mm
MG-U74CV2:137645_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOE430A:1456083_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430A_2:1456083_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MOUSE430_2:1456083_X_AT eukaryotic translation initiation factor 3, subunit 8 mm
MU19KSUBA:TC20456_AT Eukaryotic translation initiation factor 3, subunit 8 (Eif3s8), mRNA mm
MU19KSUBA:TC20456_G_AT Eukaryotic translation initiation factor 3, subunit 8 (Eif3s8), mRNA mm
MU19KSUBC:TC39050_AT Eukaryotic translation initiation factor 3, subunit 8 (Eif3s8), mRNA mm
MU19KSUBC:TC39050_G_AT Eukaryotic translation initiation factor 3, subunit 8 (Eif3s8), mRNA mm
RG-U34B:RC_AA851785_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa (predicted) rn
RAE230A:1388378_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa (predicted) rn
RAT230_2:1388378_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa (predicted) rn
RAE230B:1397674_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa (predicted) rn
RAT230_2:1397674_AT eukaryotic translation initiation factor 3, subunit 8, 110kDa (predicted) rn
YEAST_2:1771658_AT Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6413 translational initiation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5852 eukaryotic translation initiation factor 3 complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3743 translation initiation factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03403 Hypothetical protein T23D8.4 [Caenorhabditis elegans] ref|NP_492638.1| Eukaryotic Initiation Factor family member (eif-3.C) [Caenorhabditis elegans] sp|O02328|IF38_CAEEL Probable eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c) 0.0
blast CAE60247 Hypothetical protein CBG03821 [Caenorhabditis briggsae] 0.0
blast AAC27674 eIF-3 p110 subunit [Homo sapiens] 1.0E-179
Protein Domains
Database ID Description E-Value
Pfam IPR008905 EMBL-EBI Eukaryotic translation initiation factor 3 subunit 8, N-terminal 1.0E-126
Pfam IPR008904 EMBL-EBI Eukaryotic translation initiation factor 3 subunit 8, C-terminal 3.8E-8
Pfam IPR000717 EMBL-EBI Proteasome component region PCI 3.4E-36
Sequence
Target Sequence 
>C. ELEGANS:175249_S_AT
cgagccttctaaatatccatttttcaatcgtctctcccattcgtggaacccgccaatact
tgttgaatcttttatttaattgatcagtttttttggtaatcccccaccctttcccacttt
tccttgttcagtgtgagatctgaactttaaagctctcatttttcgtttccggttagtagt
gtttaagttatactctttccatactgttttgtttttgctaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGAGCCTTCTAAATATCCATTTTTC 187 251 106 Antisense
GAATCTTTTATTTAATTGATCAGTT 660 327 170 Antisense
TAATTGATCAGTTTTTTTGGTAATC 544 633 182 Antisense
TCCCACTTTTCCTTGTTCAGTGTGA 185 599 217 Antisense
TTTTCCTTGTTCAGTGTGAGATCTG 431 677 223 Antisense
AGATCTGAACTTTAAAGCTCTCATT 530 65 241 Antisense
TTAAAGCTCTCATTTTTCGTTTCCG 677 681 252 Antisense
TAGTGTTTAAGTTATACTCTTTCCA 180 653 282 Antisense
AAGTTATACTCTTTCCATACTGTTT 681 155 290 Antisense
TACTCTTTCCATACTGTTTTGTTTT 123 647 296 Antisense
TCCATACTGTTTTGTTTTTGCTAAT 216 591 303 Antisense
Sequence Source Affymetrix Proprietary Database