[Home] | [Total List]

[175163_at] serine/threonine kinase

Description AV200883_rc /REP_DB=TREMBL Accession /GB=AV200883 /CHR=3 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk582d8 : 3prime end, single read.
Cluster 6grp_high1_10_10 > 99      4grp_high_8_8 > 47      6grp_total > 94      4grp_total > 48      6grp_cgc > 89      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 149
1 2 3 4 range
A 254.9
(-3)
M 		306.4
(-0.1)
P 		359.7
(3)
P 		258.5
(-2.8)
P 		105
B 218
(-3)
P 		283.4
(-0.4)
M 		366.5
(3)
P 		300.4
(0.3)
P 		149
C 224.7
(-2.9)
P 		314.7
(1.7)
P 		341.3
(3)
P 		223
(-3)
P 		118
avr 232.5
(-3) 		301.5
(0.4) 		355.8
(3) 		260.6
(-1.6) 		123

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 414
1 2 3 4 5 6 range
A 320.4
(-0.5)
A 		303.2
(-0.7)
P 		146.4
(-3)
P 		294.8
(-0.8)
M 		559.9
(3)
P 		348
(-0.1)
P 		414
B 291.4
(-1.8)
P 		374
(-0.1)
P 		236.5
(-3)
P 		346.3
(-0.7)
P 		520.3
(3)
P 		338.9
(-0.8)
P 		284
C 304
(-0.9)
P 		316.7
(-0.7)
P 		207.6
(-3)
A 		264.2
(-1.8)
P 		489
(3)
P 		398
(1.1)
P 		281
avr 305.3
(-1) 		331.3
(-0.5) 		196.8
(-3) 		301.8
(-1.1) 		523.1
(3) 		361.6
(0) 		326
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 81
1 2 3 4 range
A 92.8
(2.9)
M 		66.5
(0.1)
P 		94
(3)
P 		37.8
(-3)
P 		56
B 69.5
(-1.4)
P 		70
(-1.3)
M 		84.9
(3)
P 		64
(-3)
P 		21
C 74.4
(-0.3)
P 		90.5
(0.9)
P 		119
(3)
P 		37.6
(-3)
P 		81
avr 78.9
(0.7) 		75.7
(0.3) 		99.3
(3) 		46.5
(-3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 180
1 2 3 4 5 6 range
A 59.1
(-1.8)
A 		107.8
(0.3)
P 		31.9
(-3)
P 		74.8
(-1.1)
M 		169
(3)
P 		84.7
(-0.7)
P 		137
B 101.4
(-1.3)
P 		124.5
(-0.4)
P 		57.4
(-3)
P 		91.7
(-1.7)
P 		211.4
(3)
P 		126.4
(-0.3)
P 		154
C 112.7
(0.4)
P 		96.6
(-0.5)
P 		52.8
(-3)
A 		53.1
(-3)
P 		158.2
(3)
P 		133.2
(1.6)
P 		105
avr 91.1
(-1) 		109.6
(-0.2) 		47.4
(-3) 		73.2
(-1.8) 		179.5
(3) 		114.8
(0.1) 		132
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175163_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21132
Sequence Type Exemplar sequence
Representative Public ID AV200883 NCBI
Target Description AV200883_rc /REP_DB=TREMBL Accession /GB=AV200883 /CHR=3 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk582d8 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065295(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065295 NCBI Caenorhabditis elegans Pim (mammalian oncogene) Related Kinase family member (prk-2) (prk-2) mRNA, complete cds. 11/11 A 
F45H7.4.1 ENSEMBL cdna:known chromosome:CEL140:III:3363658:3370198:-1 gene:F45H7.4 11/11 None
F45H7.4.2 ENSEMBL cdna:known chromosome:CEL140:III:3363672:3366797:-1 gene:F45H7.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000042112 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:3363730-3364010(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Gene Symbol prk-2
Ensembl F45H7.4
Entrez Gene 175437 Entrez gene
SwissProt Q20443 EMBL-EBI
WormBase CE31517 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.17047.1.S1_AT similar to Proto-oncogene serine/threonine-protein kinase Pim-1 cfa
CANINE_2:CFAAFFX.3073.1.S1_AT similar to Proto-oncogene serine/threonine-protein kinase Pim-1 cfa
HG-U95AV2:1779_S_AT pim-1 oncogene hs
HC-G110:1779_S_AT pim-1 oncogene hs
HG-U95AV2:883_S_AT pim-1 oncogene hs
HC-G110:883_S_AT pim-1 oncogene hs
HUGENEFL:M54915_S_AT pim-1 oncogene hs
HUGENEFL:M16750_S_AT pim-1 oncogene hs
PLASMODIUM_ANOPHELES:209193_AT pim-1 oncogene hs
HG-U133A:209193_AT pim-1 oncogene hs
HG-U133_PLUS_2:209193_AT pim-1 oncogene hs
HG-FOCUS:209193_AT pim-1 oncogene hs
HG-U133A_2:209193_AT pim-1 oncogene hs
MOUSE430A_2:1423006_AT proviral integration site 1 mm
MOUSE430_2:1423006_AT proviral integration site 1 mm
MOE430A:1423006_AT proviral integration site 1 mm
MU11KSUBB:MSA.1076.0_AT proviral integration site 1 mm
MG-U74AV2:104533_AT proviral integration site 1 mm
MG-U74AV2:99384_AT proviral integration site 1 mm
MOE430A:1435458_AT proviral integration site 1 mm
MOUSE430A_2:1435458_AT proviral integration site 1 mm
MOUSE430_2:1435458_AT proviral integration site 1 mm
MU19KSUBA:TC18356_AT Proviral integration site 1 (Pim1), mRNA mm
RAE230A:1369862_AT proviral integration site 1 rn
RAT230_2:1369862_AT proviral integration site 1 rn
RG-U34A:X63675_AT proviral integration site 1 rn
RG-U34B:RC_AI008309_AT proviral integration site 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84323 Hypothetical protein F45H7.4 [Caenorhabditis elegans] ref|NP_497696.2| Pim (mammalian oncogene) Related Kinase family member (prk-2) [Caenorhabditis elegans] 0.0
blast CAE65018 Hypothetical protein CBG09856 [Caenorhabditis briggsae] 0.0
blast CAE58266 Hypothetical protein CBG01371 [Caenorhabditis briggsae] 1.0E-114
Protein Families
Method ID Description E-Value
hanks 2.2.11 CaMK Group; CaMK II KIN1/SNF1/Nim1; YKL453 5.0E-63
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.4E-62
Sequence
Target Sequence 
>C. ELEGANS:175163_AT
cgcgttacgacgggcaatgtcaagagaggcacagaatcgaattagcggcgtcttctcgca
ggactagttttgtttctgctggaagttatcttaattttttgatttgaaaaatgtttatgt
acaaatttgaagtccttaatcttaacacaaaagccccttagctttctatttccccagaat
tctttcattttgtcgctttagaccccccaaatgcccccgacttgcgatacaaactgtacc
ggcaaaccat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCGTTACGACGGGCAATGTCAAGA 383 253 13 Antisense
GAATCGAATTAGCGGCGTCTTCTCG 536 329 46 Antisense
CGTCTTCTCGCAGGACTAGTTTTGT 44 247 61 Antisense
GGACTAGTTTTGTTTCTGCTGGAAG 187 525 73 Antisense
ATTTGAAGTCCTTAATCTTAACACA 377 13 137 Antisense
ATCTTAACACAAAAGCCCCTTAGCT 569 31 151 Antisense
CTTAGCTTTCTATTTCCCCAGAATT 291 221 169 Antisense
ATTTCCCCAGAATTCTTTCATTTTG 537 17 180 Antisense
TCTTTCATTTTGTCGCTTTAGACCC 492 615 193 Antisense
CCCCGACTTGCGATACAAACTGTAC 424 257 227 Antisense
GATACAAACTGTACCGGCAAACCAT 191 423 238 Antisense
Sequence Source Affymetrix Proprietary Database