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[175099_s_at] dehydrogenase /// ---

Description AV181849 /REP_DB=TREMBL Accession /GB=AV181849 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk625e4 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 57      6grp_high1_10_10 > 75      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 81      6grp_total > 65      4grp_total > 48      6grp_cgc > 57      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 148
1 2 3 4 range
A 256.1
(-2.8)
P 		348.4
(1.9)
P 		370.9
(3)
P 		251.6
(-3)
P 		119
B 270.1
(-3)
P 		290.4
(-1.5)
P 		350.9
(3)
P 		304.1
(-0.5)
P 		81
C 240.9
(-3)
P 		355.8
(1.7)
P 		389.1
(3)
P 		291.7
(-0.9)
P 		148
avr 255.7
(-3) 		331.5
(1) 		370.3
(3) 		282.5
(-1.6) 		115

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 238
1 2 3 4 5 6 range
A 189.1
(-3)
P 		228
(-1.7)
P 		374.1
(3)
P 		219.2
(-2)
P 		229.3
(-1.7)
P 		288.9
(0.2)
P 		185
B 317.5
(-2.2)
P 		319.7
(-2.1)
P 		355.8
(-0.4)
P 		301.6
(-3)
P 		365.2
(0)
P 		427.4
(3)
P 		126
C 288.7
(0.9)
P 		280.8
(0.4)
P 		215.2
(-3)
P 		329.7
(3)
P 		249.9
(-1.2)
P 		299.5
(1.4)
P 		115
avr 265.1
(-3) 		276.2
(-2.1) 		315
(1.1) 		283.5
(-1.5) 		281.5
(-1.7) 		338.6
(3) 		74
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 99
1 2 3 4 range
A 93.3
(2.6)
P 		75.6
(0.9)
P 		97
(3)
P 		36.8
(-3)
P 		60
B 86.1
(3)
P 		71.7
(-1.1)
P 		81.3
(1.6)
P 		64.8
(-3)
P 		21
C 79.8
(-0.9)
P 		102.3
(0.7)
P 		135.6
(3)
P 		49.2
(-3)
P 		86
avr 86.4
(1) 		83.2
(0.6) 		104.6
(3) 		50.3
(-3) 		54

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 125
1 2 3 4 5 6 range
A 34.9
(-3)
P 		81.1
(2.9)
P 		81.5
(3)
P 		55.6
(-0.3)
P 		69.2
(1.4)
P 		70.3
(1.6)
P 		47
B 110.5
(-0.7)
P 		106.4
(-1)
P 		86.4
(-2.5)
P 		79.9
(-3)
P 		148.4
(2.2)
P 		159.4
(3)
P 		80
C 107
(3)
P 		85.7
(0.6)
P 		54.8
(-3)
P 		66.3
(-1.7)
P 		80.9
(0)
P 		100.3
(2.2)
P 		52
avr 84.1
(-0.6) 		91.1
(0.3) 		74.2
(-2) 		67.3
(-3) 		99.5
(1.5) 		110
(3) 		43
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175099_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20451
Sequence Type Exemplar sequence
Representative Public ID AV181849 NCBI
Target Description AV181849 /REP_DB=TREMBL Accession /GB=AV181849 /CHR=1 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk625e4 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058325(11), NM_058326(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058325 NCBI Caenorhabditis elegans R119.3 (dehydrogenase) mRNA, complete cds. 11/11 A 
NM_058326 NCBI Caenorhabditis elegans Prion-like-(Q/N-rich)-domain-bearing protein family member (pqn-59) (pqn-59) mRNA, complete cds. 11/11 None
SNAP00000007612 ENSEMBL cdna:SNAP chromosome:CEL140:I:368778:379072:-1 10/11 None
GENEFINDER00000007617 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:368778:379099:-1 10/11 None
R119.4.2 ENSEMBL cdna:known chromosome:CEL140:I:373592:381907:-1 gene:R119.4 11/11 None
R119.4.1 ENSEMBL cdna:known chromosome:CEL140:I:373592:381905:-1 gene:R119.4 11/11 None
R119.3 ENSEMBL cdna:known chromosome:CEL140:I:373636:379078:-1 gene:R119.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:373645-377385(-) 100.0 100.0
Public Domain and Genome References
Gene Title dehydrogenase

Gene Symbol pqn-59
Ensembl R119.4
R119.3
Entrez Gene 171628 Entrez gene
266819 Entrez gene
SwissProt O61709 EMBL-EBI
O61708 EMBL-EBI
WormBase CE28758 Wormbase
CE23925 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAD47125 Prion-like-(q/n-rich)-domain-bearing protein protein 59 [Caenorhabditis elegans] ref|NP_490727.1| Prion-like-(Q/N-rich)-domain-bearing protein family member (pqn-59) [Caenorhabditis elegans] 0.0
blast D87719 protein R119.4 [imported] - Caenorhabditis elegans 0.0
blast CAE74547 Hypothetical protein CBG22304 [Caenorhabditis briggsae] 0.0
blast AAC16431 Hypothetical protein R119.2 [Caenorhabditis elegans] ref|NP_490725.2| R119.2 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 7.6E-37
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 3.8E-33
Pfam IPR000994 EMBL-EBI Peptidase M24 2.0E-14
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 3.4E-31
Pfam IPR000994 EMBL-EBI Peptidase M24 2.0E-14
Sequence
Target Sequence 
>C. ELEGANS:175099_S_AT
cgcgtgaatagtgtggtgtctggaatgattgaaggagacggaactggtgctgtatgggat
catgcttctggagaagaagctcgtcagattaaacaacacttggaatcgatgattccgttg
ggaagacttggaagaccgtctgatgttgcttcttatgtcgaatttttggcttctaccaaa
gccaggta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCGTGAATAGTGTGGTGTCTGGAA 520 255 13 Antisense
TGTGGTGTCTGGAATGATTGAAGGA 91 555 24 Antisense
GAAGGAGACGGAACTGGTGCTGTAT 542 333 43 Antisense
GACGGAACTGGTGCTGTATGGGATC 125 377 49 Antisense
CTGGTGCTGTATGGGATCATGCTTC 604 239 56 Antisense
GAAGCTCGTCAGATTAAACAACACT 589 341 88 Antisense
TCCGTTGGGAAGACTTGGAAGACCG 355 353 126 Antisense
GGAAGACCGTCTGATGTTGCTTCTT 435 531 142 Antisense
CGTCTGATGTTGCTTCTTATGTCGA 132 247 149 Antisense
GATGTTGCTTCTTATGTCGAATTTT 238 411 154 Antisense
TTTTGGCTTCTACCAAAGCCAGGTA 32 677 176 Antisense
Sequence Source Affymetrix Proprietary Database