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[175084_s_at] protein tyrosine kinase

Description C59637_rc /REP_DB=TREMBL Accession /GB=C59637 /CHR=X /FEA=Genomic Cluster /REVCOMP /DEF=C.elegans cDNA clone yk439e9 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 24      6grp_high1_10_10 > 31      4grp_highest_8_8 > 40      4grp_high_8_8 > 43      6grp_highest_nonorm > 90      6grp_total > 21      4grp_total > 44      6grp_high1_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 105
1 2 3 4 range
A 182.9
(0.1)
P 		223.4
(3)
P 		138.4
(-3)
P 		140.6
(-2.8)
P 		85
B 135.7
(0.9)
P 		143.6
(3)
P 		127.6
(-1.3)
P 		121.1
(-3)
P 		23
C 207.8
(3)
P 		208.3
(3)
P 		177
(0.9)
P 		118.9
(-3)
P 		89
avr 175.5
(1.5) 		191.8
(3) 		147.7
(-1.1) 		126.9
(-3) 		65

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 196
1 2 3 4 5 6 range
A 176.6
(2)
P 		130.8
(0.3)
P 		204
(3)
P 		114.2
(-0.4)
P 		172.8
(1.8)
P 		43.6
(-3)
P 		160
B 165.5
(-0.7)
P 		188.5
(0.5)
P 		239.5
(3)
P 		161.7
(-0.8)
P 		118.2
(-3)
P 		153.8
(-1.2)
P 		121
C 102
(-3)
P 		183.3
(3)
P 		101.9
(-3)
P 		123.6
(-1.4)
P 		113.8
(-2.1)
P 		125.3
(-1.3)
P 		81
avr 148
(0.3) 		167.5
(1.8) 		181.8
(3) 		133.2
(-0.9) 		134.9
(-0.8) 		107.6
(-3) 		74
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 66.6
(3)
P 		48.5
(0.6)
P 		36.2
(-1)
P 		20.6
(-3)
P 		46
B 43.3
(3)
P 		35.5
(0.3)
P 		29.6
(-1.7)
P 		25.8
(-3)
P 		18
C 68.8
(3)
P 		59.9
(1.9)
P 		61.7
(2.1)
P 		20.1
(-3)
P 		49
avr 59.6
(3) 		48
(1.1) 		42.5
(0.3) 		22.2
(-3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 52
1 2 3 4 5 6 range
A 32.6
(0.2)
P 		46.5
(2.2)
P 		44.4
(1.9)
P 		29
(-0.3)
P 		52.1
(3)
P 		10.6
(-3)
P 		42
B 57.6
(1.4)
P 		62.8
(3)
P 		58.2
(1.6)
P 		42.8
(-3)
P 		48
(-1.4)
P 		57.3
(1.4)
P 		20
C 37.8
(-0.5)
P 		55.9
(3)
P 		25.9
(-2.8)
P 		24.9
(-3)
P 		36.8
(-0.7)
P 		41.9
(0.3)
P 		31
avr 42.7
(-0.2) 		55.1
(3) 		42.8
(-0.2) 		32.2
(-3) 		45.6
(0.5) 		36.6
(-1.8) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175084_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.28250
Sequence Type Exemplar sequence
Representative Public ID C59637 NCBI
Target Description C59637_rc /REP_DB=TREMBL Accession /GB=C59637 /CHR=X /FEA=Genomic Cluster /REVCOMP /DEF=C.elegans cDNA clone yk439e9 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078268(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078268 NCBI Caenorhabditis elegans F38E9.5 (F38E9.5) mRNA, complete cds. 11/11 A 
GENEFINDER00000030346 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:16446400:16450804:1 11/11 None
SNAP00000030335 ENSEMBL cdna:SNAP chromosome:CEL140:X:16447775:16450804:1 11/11 None
F38E9.5.2 ENSEMBL cdna:known chromosome:CEL140:X:16446115:16451250:1 gene:F38E9.5 11/11 A 
F38E9.5.1 ENSEMBL cdna:known chromosome:CEL140:X:16446115:16451248:1 gene:F38E9.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:16447841-16448779(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein tyrosine kinase
Ensembl F38E9.5
Entrez Gene 181711 Entrez gene
SwissProt Q20173 EMBL-EBI
WormBase CE28307 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.20762.1.S1_S_AT similar to twinfilin isoform 1 cfa
CANINE_2:CFAAFFX.15169.1.S1_AT similar to twinfilin isoform 1 cfa
DROSOPHILA_2:1627488_AT twinfilin dm
DROSGENOME1:154805_AT twinfilin dm
CHICKEN:GGAAFFX.11804.1.S1_AT PTK9 protein tyrosine kinase 9 gga
CHICKEN:GGAAFFX.6023.1.S1_AT PTK9 protein tyrosine kinase 9 gga
HG-U95AV2:1064_AT PTK9 protein tyrosine kinase 9 hs
HC-G110:1064_AT PTK9 protein tyrosine kinase 9 hs
HG-U133_PLUS_2:201745_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A:201745_AT PTK9 protein tyrosine kinase 9 hs
HG-FOCUS:201745_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A_2:201745_AT PTK9 protein tyrosine kinase 9 hs
HG-U133_PLUS_2:214007_S_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A_2:214007_S_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A:214007_S_AT PTK9 protein tyrosine kinase 9 hs
HUGENEFL:U02680_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:G4506274_3P_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:HS.82643.1.S1_3P_A_AT PTK9 protein tyrosine kinase 9 hs
HG-U133_PLUS_2:214008_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A_2:214008_AT PTK9 protein tyrosine kinase 9 hs
HG-U133A:214008_AT PTK9 protein tyrosine kinase 9 hs
HG-U133_PLUS_2:243033_AT PTK9 protein tyrosine kinase 9 hs
HG-U133B:243033_AT PTK9 protein tyrosine kinase 9 hs
HG-U133_PLUS_2:244199_AT PTK9 protein tyrosine kinase 9 hs
HG-U133B:244199_AT PTK9 protein tyrosine kinase 9 hs
HG-U95E:68000_AT PTK9 protein tyrosine kinase 9 hs
HG-U95E:69999_R_AT PTK9 protein tyrosine kinase 9 hs
HG-U95E:70002_F_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:HS.189075.0.S1_3P_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:HS.202492.0.A1_3P_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:HS.202492.0.A1_3P_X_AT PTK9 protein tyrosine kinase 9 hs
U133_X3P:HS.82643.1.A1_3P_AT PTK9 protein tyrosine kinase 9 hs
MG-U74AV2:93646_AT protein tyrosine kinase 9 mm
MG-U74BV2:162915_AT protein tyrosine kinase 9 mm
MOE430A:1420873_AT protein tyrosine kinase 9 mm
MOUSE430A_2:1420873_AT protein tyrosine kinase 9 mm
MOUSE430_2:1420873_AT protein tyrosine kinase 9 mm
MOE430A:1420875_AT protein tyrosine kinase 9 mm
MOUSE430A_2:1420875_AT protein tyrosine kinase 9 mm
MOUSE430_2:1420875_AT protein tyrosine kinase 9 mm
MOE430A:1420874_AT protein tyrosine kinase 9 mm
MOUSE430A_2:1420874_AT protein tyrosine kinase 9 mm
MOUSE430_2:1420874_AT protein tyrosine kinase 9 mm
MU19KSUBC:TC40025_AT Protein tyrosine kinase 9, mRNA (cDNA clone MGC:13938 IMAGE:3979221) mm
MU19KSUBC:TC40025_G_AT Protein tyrosine kinase 9, mRNA (cDNA clone MGC:13938 IMAGE:3979221) mm
RG-U34A:RC_AA892851_AT protein tyrosine kinase 9 (predicted) rn
RG-U34A:RC_AA892851_G_AT protein tyrosine kinase 9 (predicted) rn
RG-U34C:RC_AI171354_AT protein tyrosine kinase 9 (predicted) rn
RAE230A:1376365_AT protein tyrosine kinase 9 (predicted) rn
RAT230_2:1376365_AT protein tyrosine kinase 9 (predicted) rn
RAE230A:1371644_AT protein tyrosine kinase 9 (predicted) rn
RAT230_2:1371644_AT protein tyrosine kinase 9 (predicted) rn
RG-U34B:RC_AI043716_AT Protein tyrosine kinase 9 (predicted) rn
YEAST_2:1769481_AT Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly Sc
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3779 actin binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA93345 Hypothetical protein F38E9.5 [Caenorhabditis elegans] ref|NP_510669.1| F38E9.5 [Caenorhabditis elegans] 1.0E-176
blast AAA93345 Hypothetical protein F38E9.5 [Caenorhabditis elegans] ref|NP_510669.1| F38E9.5 [Caenorhabditis elegans] 1.0E-173
blast CAE69968 Hypothetical protein CBG16364 [Caenorhabditis briggsae] 1.0E-169
blast CAE69968 Hypothetical protein CBG16364 [Caenorhabditis briggsae] 1.0E-166
Protein Domains
Database ID Description E-Value
Pfam IPR002108 EMBL-EBI Actin-binding, cofilin/tropomyosin type 1.5E-6
Pfam IPR002108 EMBL-EBI Actin-binding, cofilin/tropomyosin type 2.2E-5
Pfam IPR002108 EMBL-EBI Actin-binding, cofilin/tropomyosin type 1.5E-6
Pfam IPR002108 EMBL-EBI Actin-binding, cofilin/tropomyosin type 2.2E-5
Sequence
Target Sequence 
>C. ELEGANS:175084_S_AT
aactgaggctcatcaagattgtggtgaataatgaggagatgacgccgaactacgagtttg
ctggaaccgccaactggcgtgacgactggagggcttgcttgccggactgtgtggatgcct
acgagccgtgcttcattctgttccggttgaataccatcacagaatgggttttgatcacag
gtttgtcgacgatcgtgctccagtccgtgaaaagatgcttctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACTGAGGCTCATCAAGATTGTGGT 54 143 16 Antisense
TGAGGAGATGACGCCGAACTACGAG 321 567 47 Antisense
GAACTACGAGTTTGCTGGAACCGCC 152 349 62 Antisense
TTTGCTGGAACCGCCAACTGGCGTG 325 667 72 Antisense
GGAACCGCCAACTGGCGTGACGACT 19 529 78 Antisense
AACTGGCGTGACGACTGGAGGGCTT 344 143 87 Antisense
TTGCTTGCCGGACTGTGTGGATGCC 517 701 110 Antisense
TGCTTCATTCTGTTCCGGTTGAATA 398 579 144 Antisense
GTTCCGGTTGAATACCATCACAGAA 304 441 155 Antisense
CCATCACAGAATGGGTTTTGATCAC 306 271 169 Antisense
TCCAGTCCGTGAAAAGATGCTTCTG 63 591 214 Antisense
Sequence Source Affymetrix Proprietary Database