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[175013_at] casein kinase

Description CEK071EZR_rc /REP_DB=TREMBL Accession /GB=D65952 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk71e12 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 91      6grp_high1_10_10 > 49      4grp_highest_8_8 > 23      4grp_high_8_8 > 05      6grp_highest_nonorm > 47      6grp_total > 39      4grp_total > 03      6grp_cgc > 09      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8049
1 2 3 4 range
A 4979.3
(-2.3)
P 		4268.8
(-3)
P 		4244.5
(-3)
P 		10547.1
(3)
P 		6303
B 5067.5
(-1.3)
P 		3949.3
(-2.5)
P 		3482.4
(-3)
P 		9090.2
(3)
P 		5608
C 4785.9
(-3)
P 		4942.3
(-2.9)
P 		5005
(-2.8)
P 		11531.6
(3)
P 		6746
avr 4944.2
(-2.3) 		4386.8
(-2.9) 		4244
(-3) 		10389.6
(3) 		6146

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1409
1 2 3 4 5 6 range
A 4082.8
(2.9)
P 		3884.5
(1.6)
P 		3150.3
(-3)
P 		3259.3
(-2.3)
P 		4105.2
(3)
P 		3855.3
(1.4)
P 		955
B 4250.1
(2.9)
P 		4249
(2.9)
P 		2865.4
(-3)
P 		4274.6
(3)
P 		3721.4
(0.6)
P 		3775.2
(0.9)
P 		1409
C 3973
(2.5)
P 		3536.8
(-3)
P 		3579.8
(-2.5)
P 		4011.1
(3)
P 		3587.6
(-2.4)
P 		3856.2
(1)
P 		474
avr 4102
(3) 		3890.1
(1.6) 		3198.5
(-3) 		3848.3
(1.3) 		3804.7
(1) 		3828.9
(1.2) 		904
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1137
1 2 3 4 range
A 1813
(3)
P 		926.6
(-3)
P 		1109.6
(-1.8)
P 		1543.9
(1.2)
P 		886
B 1616
(1.3)
P 		975.4
(-2.1)
P 		807
(-3)
P 		1937.1
(3)
P 		1130
C 1584.3
(-1.1)
P 		1420.9
(-3)
P 		1744.4
(0.7)
P 		1944.4
(3)
P 		524
avr 1671.1
(1.8) 		1107.6
(-3) 		1220.3
(-2) 		1808.5
(3) 		701

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 826
1 2 3 4 5 6 range
A 752.6
(-2.4)
P 		1381.5
(3)
P 		686.1
(-3)
P 		826.6
(-1.8)
P 		1238.8
(1.8)
P 		938.6
(-0.8)
P 		695
B 1478.8
(2.8)
P 		1414.3
(2.3)
P 		695.8
(-3)
P 		1132.2
(0.2)
P 		1511.9
(3)
P 		1407.8
(2.2)
P 		816
C 1472.6
(3)
P 		1079.2
(-0.5)
P 		911.1
(-2.1)
P 		806.6
(-3)
P 		1160.9
(0.2)
P 		1290.9
(1.4)
P 		666
avr 1234.7
(2.2) 		1291.7
(2.9) 		764.3
(-3) 		921.8
(-1.2) 		1303.9
(3) 		1212.4
(2) 		540
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175013_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20186
Sequence Type Exemplar sequence
Representative Public ID CEK071EZR NCBI
Target Description CEK071EZR_rc /REP_DB=TREMBL Accession /GB=D65952 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk71e12 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060410(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060410 NCBI Caenorhabditis elegans protein KINase family member (kin-3) (kin-3) mRNA, complete cds. 11/11 None
B0205.7.1 ENSEMBL cdna:known chromosome:CEL140:I:10742139:10744730:1 gene:B0205.7 11/11 None
B0205.7.2 ENSEMBL cdna:known chromosome:CEL140:I:10742143:10744730:1 gene:B0205.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10744295-10744619(+) 100.0 100.0
Public Domain and Genome References
Gene Title casein kinase
Gene Symbol kin-3
Ensembl B0205.7
Entrez Gene 172978 Entrez gene
SwissProt P18334 EMBL-EBI
WormBase CE17321 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16146_AT casein kinase II alpha chain 2 at
ATH1-121501:252192_AT casein kinase II alpha chain 2 at
CANINE:1587516_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE:1585359_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFA.10060.1.A1_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFAAFFX.11318.1.S1_AT similar to casein kinase II alpha 1 subunit isoform a cfa
CANINE_2:CFAAFFX.11318.1.S1_S_AT similar to casein kinase II alpha 1 subunit isoform a cfa
DROSOPHILA_2:1640051_S_AT Casein kinase II subunit dm
HG-U95AV2:594_S_AT casein kinase 2, alpha 1 polypeptide hs
HC-G110:594_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212073_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-FOCUS:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212072_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:206075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A_2:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133A:212075_S_AT casein kinase 2, alpha 1 polypeptide hs
HUGENEFL:M55265_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:G4503094_3P_A_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S3_3P_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S2_3P_AT casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.3.S1_3P_A_AT casein kinase 2, alpha 1 polypeptide hs
HG-U95AV2:40258_AT casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:229212_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:229212_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:237907_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:237907_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133_PLUS_2:239228_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U133B:239228_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95AV2:36235_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95C:60425_AT Casein kinase 2, alpha 1 polypeptide hs
HG-U95E:74832_AT Casein kinase 2, alpha 1 polypeptide hs
HU35KSUBB:RC_D60799_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.155140.2.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.282945.0.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
U133_X3P:HS.292385.0.A1_3P_AT Casein kinase 2, alpha 1 polypeptide hs
MOUSE430_2:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1453427_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419038_A_AT casein kinase II, alpha 1 polypeptide mm
MU11KSUBA:AA266026_S_AT casein kinase II, alpha 1 polypeptide mm
MU11KSUBA:U51866_S_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:103441_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:104545_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:104546_G_AT casein kinase II, alpha 1 polypeptide mm
MG-U74AV2:160690_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419037_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419035_S_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419034_AT casein kinase II, alpha 1 polypeptide mm
MOE430A:1419036_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430A_2:1419036_AT casein kinase II, alpha 1 polypeptide mm
MOUSE430_2:1419036_AT casein kinase II, alpha 1 polypeptide mm
MU19KSUBB:TC31462_AT Casein kinase II, alpha 1 polypeptide, mRNA (cDNA clone MGC:13987 IMAGE:4188101) mm
RG-U34A:L15618_AT casein kinase II, alpha 1 polypeptide rn
RG-U34B:RC_AI012245_AT casein kinase II, alpha 1 polypeptide rn
RAE230A:1387170_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1387170_AT casein kinase II, alpha 1 polypeptide rn
RAE230B:1392650_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1392650_AT casein kinase II, alpha 1 polypeptide rn
RAE230B:1384339_S_AT casein kinase II, alpha 1 polypeptide rn
RAT230_2:1384339_S_AT casein kinase II, alpha 1 polypeptide rn
RAE230A:1375636_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1375636_AT Casein kinase II, alpha 1 polypeptide rn
RAE230A:1376616_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1376616_AT Casein kinase II, alpha 1 polypeptide rn
RAE230A:1389974_AT Casein kinase II, alpha 1 polypeptide rn
RAT230_2:1389974_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AA800210_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AA875506_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34B:RC_AA899254_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34C:RC_AI179620_AT Casein kinase II, alpha 1 polypeptide rn
RG-U34A:RC_AI072089_AT Casein kinase II, alpha 1 polypeptide rn
YEAST_2:1771598_AT Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC16993 Protein kinase protein 3 [Caenorhabditis elegans] ref|NP_492811.1| protein KINase family member (kin-3) [Caenorhabditis elegans] sp|P18334|CSK2A_CAEEL Casein kinase II, alpha chain (CK II alpha subunit) gb|AAA27984.1| casein kinase II-alpha 0.0
blast CAE67357 Hypothetical protein CBG12820 [Caenorhabditis briggsae] 1.0E-179
blast NP_001002242 casein kinase II alpha subunit [Gallus gallus] ref|XP_417444.1| PREDICTED: similar to casein kinase II (EC 2.7.1.-) alpha chain - chicken [Gallus gallus] sp|P21868|CSK21_CHICK Casein kinase II, alpha chain (CK II) gb|AAA48691.1| casein kinase II alpha subunit 1.0E-154
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-23
hanks 3.1.3 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk3 6.0E-30
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.7E-79
Sequence
Target Sequence 
>C. ELEGANS:175013_AT
tccatcattattcctttgctctaaaaattggctaagatattaaatcttccccgcttctcc
gaaaatttccctctacgtaccacaaaagtgcctaatcttttcgtgagaaacgttctttgc
aaattctatttttaggatttttttgtgtaattcatgcctctgaaattccgtttcaatttt
aaatcttttttgtcccatttcatattgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCATCATTATTCCTTTGCTCTAAA 516 591 82 Antisense
ATTCCTTTGCTCTAAAAATTGGCTA 430 3 91 Antisense
AAGATATTAAATCTTCCCCGCTTCT 321 155 115 Antisense
TTCCCTCTACGTACCACAAAAGTGC 323 693 148 Antisense
ACGTACCACAAAAGTGCCTAATCTT 226 79 156 Antisense
AGTGCCTAATCTTTTCGTGAGAAAC 670 59 168 Antisense
GAAACGTTCTTTGCAAATTCTATTT 537 355 188 Antisense
TTTTGTGTAATTCATGCCTCTGAAA 114 679 222 Antisense
ATGCCTCTGAAATTCCGTTTCAATT 326 41 235 Antisense
TTAAATCTTTTTTGTCCCATTTCAT 223 683 260 Antisense
CTTTTTTGTCCCATTTCATATTGTT 449 221 266 Antisense
Sequence Source Affymetrix Proprietary Database