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[174984_at] Transducin beta chain

Description CEK022DYR_rc /REP_DB=TREMBL Accession /GB=D64808 /CHR=2 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk22d11 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 83      6grp_high1_10_10 > 48      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 74      6grp_total > 48      4grp_total > 23      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 432
1 2 3 4 range
A 894.1
(3)
P 		471.2
(-3)
P 		538.8
(-2)
P 		760.9
(1.1)
P 		423
B 772.6
(3)
P 		597.6
(-0.4)
P 		461.7
(-3)
P 		712.3
(1.8)
P 		311
C 597.8
(-3)
P 		665.4
(3)
P 		597.3
(-3)
P 		648.5
(1.5)
P 		68
avr 754.8
(3) 		578.1
(-1.8) 		532.6
(-3) 		707.2
(1.7) 		222

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 471
1 2 3 4 5 6 range
A 734.8
(0.9)
P 		556.1
(-1.7)
P 		506.7
(-2.4)
P 		466.6
(-3)
P 		701.7
(0.4)
P 		879.8
(3)
P 		413
B 937.5
(3)
P 		784.8
(0.6)
P 		625.4
(-2)
P 		662.5
(-1.4)
P 		561.5
(-3)
P 		789.9
(0.6)
P 		376
C 900.6
(3)
P 		629.8
(-1.4)
P 		586.6
(-2.1)
P 		605.9
(-1.8)
P 		531.8
(-3)
P 		731.3
(0.2)
P 		369
avr 857.6
(3) 		656.9
(-1.2) 		572.9
(-3) 		578.3
(-2.9) 		598.3
(-2.5) 		800.3
(1.8) 		285
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 223
1 2 3 4 range
A 325.5
(3)
P 		102.3
(-3)
P 		140.9
(-2)
P 		111.4
(-2.8)
P 		223
B 246.4
(3)
P 		147.6
(-1.3)
P 		107
(-3)
P 		151.8
(-1.1)
P 		139
C 197.9
(2.4)
P 		191.3
(2)
P 		208.2
(3)
P 		109.4
(-3)
P 		99
avr 256.6
(3) 		147.1
(-2) 		152
(-1.7) 		124.2
(-3) 		132

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 224
1 2 3 4 5 6 range
A 135.5
(-1.5)
P 		197.8
(2.1)
P 		110.3
(-3)
P 		118.3
(-2.5)
P 		211.8
(2.9)
P 		214.2
(3)
P 		104
B 326.2
(3)
P 		261.2
(0.8)
P 		151.9
(-3)
P 		175.5
(-2.2)
P 		228.1
(-0.4)
P 		294.5
(1.9)
P 		174
C 333.8
(3)
P 		192.2
(-1)
P 		149.3
(-2.2)
P 		121.8
(-3)
P 		172.1
(-1.6)
P 		244.8
(0.5)
P 		212
avr 265.2
(3) 		217.1
(0.7) 		137.2
(-3) 		138.5
(-2.9) 		204
(0.1) 		251.2
(2.3) 		128
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174984_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20786
Sequence Type Exemplar sequence
Representative Public ID CEK022DYR NCBI
Target Description CEK022DYR_rc /REP_DB=TREMBL Accession /GB=D64808 /CHR=2 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk22d11 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062884(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062884 NCBI Caenorhabditis elegans abnormal cell LINeage family member (lin-23) (lin-23) mRNA, complete cds. 11/11 A 
K10B2.1 ENSEMBL cdna:known chromosome:CEL140:II:6371252:6374489:1 gene:K10B2.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:6374126-6374439(+) 98.74 98.74
Public Domain and Genome References
Gene Title Transducin beta chain
Gene Symbol lin-23
Ensembl K10B2.1
Entrez Gene 174058 Entrez gene
SwissProt Q09990 EMBL-EBI
WormBase CE28600 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.15509.1.S1_S_AT similar to F-box/WD-repeat protein 1A (F-box and WD-repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) cfa
DROSOPHILA_2:1635960_AT supernumerary limbs dm
DROSGENOME1:153633_AT supernumerary limbs dm
CHICKEN:GGAAFFX.4891.2.S1_S_AT similar to F-box/WD-repeat protein 1A (F-box and WD-repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) gga
HG-U133_PLUS_2:216091_S_AT beta-transducin repeat containing hs
HG-U133A_2:216091_S_AT beta-transducin repeat containing hs
HG-FOCUS:216091_S_AT beta-transducin repeat containing hs
HG-U133A:216091_S_AT beta-transducin repeat containing hs
HU35KSUBA:RC_AA350771_S_AT beta-transducin repeat containing hs
HU35KSUBB:RC_N58485_AT beta-transducin repeat containing hs
HG-U133B:224471_S_AT beta-transducin repeat containing hs
HG-U133_PLUS_2:224471_S_AT beta-transducin repeat containing hs
U133_X3P:G13623214_3P_S_AT beta-transducin repeat containing hs
U133_X3P:HS2.376908.1.S1_3P_AT beta-transducin repeat containing hs
U133_X3P:HS.226434.1.S1_3P_A_AT beta-transducin repeat containing hs
U133_X3P:HS.226434.0.S2_3P_AT beta-transducin repeat containing hs
U133_X3P:HS.170212.0.A1_3P_AT beta-transducin repeat containing hs
HG-U133_PLUS_2:1563620_AT beta-transducin repeat containing hs
HG-U133A_2:204901_AT beta-transducin repeat containing hs
HG-U133_PLUS_2:204901_AT beta-transducin repeat containing hs
HG-U133A:204901_AT beta-transducin repeat containing hs
HG-U133A_2:222374_AT beta-transducin repeat containing hs
HG-U133_PLUS_2:222374_AT beta-transducin repeat containing hs
HG-U133A:222374_AT beta-transducin repeat containing hs
HG-U95AV2:39303_AT beta-transducin repeat containing hs
HG-U95AV2:39304_G_AT beta-transducin repeat containing hs
HG-U95AV2:39305_AT beta-transducin repeat containing hs
HG-U95B:45239_AT beta-transducin repeat containing hs
HG-U95C:60838_AT beta-transducin repeat containing hs
HG-U95D:85189_AT beta-transducin repeat containing hs
MU11KSUBA:AA189349_S_AT beta-transducin repeat containing protein mm
MG-U74AV2:96224_AT beta-transducin repeat containing protein mm
MG-U74CV2:130852_AT beta-transducin repeat containing protein mm
MG-U74AV2:160790_S_AT beta-transducin repeat containing protein mm
MOE430A:1425680_A_AT beta-transducin repeat containing protein mm
MOUSE430A_2:1425680_A_AT beta-transducin repeat containing protein mm
MOUSE430_2:1425680_A_AT beta-transducin repeat containing protein mm
MOE430A:1417325_AT beta-transducin repeat containing protein mm
MOUSE430A_2:1417325_AT beta-transducin repeat containing protein mm
MOUSE430_2:1417325_AT beta-transducin repeat containing protein mm
MOE430B:1446925_AT beta-transducin repeat containing protein mm
MOUSE430_2:1446925_AT beta-transducin repeat containing protein mm
MOE430B:1443142_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOUSE430_2:1443142_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MG-U74BV2:106119_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOE430B:1447120_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOUSE430_2:1447120_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOUSE430_2:1456780_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOE430B:1456780_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOE430B:1457305_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MOUSE430_2:1457305_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
MU19KSUBA:TC19975_AT Beta-transducin repeat containing protein, mRNA (cDNA clone MGC:7517 IMAGE:3491843) mm
RG-U34C:RC_AI179552_AT beta-transducin repeat containing rn
RAE230A:1374654_AT beta-transducin repeat containing rn
RAT230_2:1374654_AT beta-transducin repeat containing rn
Protein Similarities
Method ID Description E-Value
blast AAA68258 Abnormal cell lineage protein 23 [Caenorhabditis elegans] ref|NP_495285.1| abnormal cell LINeage family member (lin-23) [Caenorhabditis elegans] gb|AAG28037.1| LIN-23 [Caenorhabditis elegans] sp|Q09990|LIN23_CAEEL F-box/WD-repeat protein lin-23 (Abnormal cell lineage protein 23) 0.0
blast T16607 hypothetical protein K10B2.1 - Caenorhabditis elegans 0.0
blast CAE59305 Hypothetical protein CBG02640 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001810 EMBL-EBI Cyclin-like F-box 5.4E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.8E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.7E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 7.8E-8
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.5E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.4E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.1E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.4E-6
Sequence
Target Sequence 
>C. ELEGANS:174984_AT
gtttttgtaaccgcattcgagtcctggtttttctgaaactatttttttaatacttcaatt
ttcaaagtcgcatgctttgcgggtgcccattcatccactctcaccattttattttgtttt
tcatccctcttcccatttctcaacggtttttcttctacggcgacgattctaaatgcttct
atcccccgctttcctcacccgcacattttcaatcgcttcacacaaatctgtttcaaataa
tcgttttcgttcctaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTTTTGTAACCGCATTCGAGTCCT 156 445 19 Antisense
CGCATTCGAGTCCTGGTTTTTCTGA 485 253 30 Antisense
GAGTCCTGGTTTTTCTGAAACTATT 630 387 37 Antisense
AATACTTCAATTTTCAAAGTCGCAT 215 173 67 Antisense
CAAAGTCGCATGCTTTGCGGGTGCC 332 193 81 Antisense
CATCCACTCTCACCATTTTATTTTG 506 211 110 Antisense
TTTTTCTTCTACGGCGACGATTCTA 64 673 165 Antisense
ACGATTCTAAATGCTTCTATCCCCC 356 91 181 Antisense
CACATTTTCAATCGCTTCACACAAA 3 197 220 Antisense
ATCGCTTCACACAAATCTGTTTCAA 590 37 230 Antisense
TCAAATAATCGTTTTCGTTCCTAAT 538 623 251 Antisense
Sequence Source Affymetrix Proprietary Database