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[174971_at] nuclear autoantigen

Description CEK131A3R_rc /REP_DB=TREMBL Accession /GB=D65093 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk131a3 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 75      6grp_high1_10_10 > 57      4grp_highest_8_8 > 43      4grp_high_8_8 > 24      6grp_highest_nonorm > 82      6grp_total > 58      4grp_total > 47      6grp_highest_sub > Cu      6grp_cgc > 39      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 221
1 2 3 4 range
A 476.6
(3)
P 		339.7
(-0.8)
P 		396.3
(0.7)
P 		262.8
(-3)
P 		214
B 337.4
(1.4)
P 		271.7
(-2.1)
P 		255.3
(-3)
P 		366
(3)
P 		111
C 334
(3)
P 		259.7
(-3)
P 		278.5
(-1.5)
P 		306.9
(0.8)
P 		74
avr 382.7
(3) 		290.4
(-3) 		310
(-1.7) 		311.9
(-1.6) 		92

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 437
1 2 3 4 5 6 range
A 265
(-2.9)
P 		324.9
(-1.7)
P 		259.8
(-3)
P 		327.5
(-1.6)
P 		433
(0.5)
P 		554.6
(3)
P 		295
B 303.5
(-1.9)
P 		232.6
(-3)
P 		325.6
(-1.6)
P 		341.2
(-1.3)
P 		254.4
(-2.7)
P 		620
(3)
P 		387
C 669.6
(3)
P 		316.9
(-2)
P 		242.4
(-3)
P 		314.5
(-2)
P 		294.6
(-2.3)
P 		422.8
(-0.5)
P 		427
avr 412.7
(0.2) 		291.5
(-2.6) 		275.9
(-3) 		327.7
(-1.8) 		327.3
(-1.8) 		532.5
(3) 		257
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 135
1 2 3 4 range
A 173.5
(3)
P 		73.7
(-1.4)
P 		103.6
(-0.1)
P 		38.5
(-3)
P 		135
B 107.6
(3)
P 		67.1
(-2)
P 		59.2
(-3)
P 		78
(-0.7)
P 		48
C 110.6
(3)
P 		74.7
(-0.7)
P 		97.1
(1.6)
P 		51.8
(-3)
P 		59
avr 130.6
(3) 		71.8
(-1.7) 		86.6
(-0.5) 		56.1
(-3) 		75

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 199
1 2 3 4 5 6 range
A 48.8
(-3)
P 		115.6
(1.6)
P 		56.6
(-2.5)
P 		83
(-0.6)
P 		130.7
(2.7)
P 		135
(3)
P 		86
B 105.6
(-1.9)
P 		77.4
(-3)
P 		79.1
(-2.9)
P 		90.4
(-2.5)
P 		103.4
(-2)
P 		231.2
(3)
P 		154
C 248.2
(3)
P 		96.7
(-1.9)
P 		61.7
(-3)
P 		63.3
(-2.9)
P 		95.3
(-1.9)
P 		141.5
(-0.4)
P 		187
avr 134.2
(1) 		96.6
(-1.2) 		65.8
(-3) 		78.9
(-2.2) 		109.8
(-0.4) 		169.2
(3) 		103
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174971_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21747
Sequence Type Exemplar sequence
Representative Public ID CEK131A3R NCBI
Target Description CEK131A3R_rc /REP_DB=TREMBL Accession /GB=D65093 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk131a3 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073263(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073263 NCBI Caenorhabditis elegans K07C5.8 (K07C5.8) mRNA, complete cds. 11/11 None
K07C5.8 ENSEMBL cdna:known chromosome:CEL140:V:10364907:10368771:1 gene:K07C5.8 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000028831 2/11 Cross Hyb Matching Probes None
GENEFINDER00000028844 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10367667-10367980(+) 100.0 100.0
Public Domain and Genome References
Gene Title nuclear autoantigen
Gene Symbol cash-1
Ensembl K07C5.8
Entrez Gene 179445 Entrez gene
SwissProt Q17406 EMBL-EBI
WormBase CE35585 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CHICKEN:GGAAFFX.23076.1.S1_S_AT similar to Striatin 3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen) gga
MU11KSUBA:AA138853_S_AT striatin, calmodulin binding protein 3 mm
MG-U74AV2:100878_AT striatin, calmodulin binding protein 3 mm
MG-U74BV2:162577_AT striatin, calmodulin binding protein 3 mm
MOE430A:1423535_AT striatin, calmodulin binding protein 3 mm
MOUSE430A_2:1423535_AT striatin, calmodulin binding protein 3 mm
MOUSE430_2:1423535_AT striatin, calmodulin binding protein 3 mm
MOE430A:1423536_AT striatin, calmodulin binding protein 3 mm
MOUSE430A_2:1423536_AT striatin, calmodulin binding protein 3 mm
MOUSE430_2:1423536_AT striatin, calmodulin binding protein 3 mm
MOE430B:1441266_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
MOUSE430_2:1441266_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
MU19KSUBC:TC36769_AT Striatin, calmodulin binding protein 3 (Strn3), mRNA mm
RG-U34C:RC_AI172489_AT striatin, calmodulin binding protein 3 rn
RAE230A:1375537_AT striatin, calmodulin binding protein 3 rn
RAT230_2:1375537_AT striatin, calmodulin binding protein 3 rn
RG-U34A:RC_AA875215_AT Striatin, calmodulin binding protein 3 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4190 aspartic-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94873 Hypothetical protein K07C5.8 [Caenorhabditis elegans] emb|CAA94901.2| Hypothetical protein K07C5.8 [Caenorhabditis elegans] ref|NP_505664.2| K07C5.8 [Caenorhabditis elegans] 0.0
blast CAE64801 Hypothetical protein CBG09594 [Caenorhabditis briggsae] 0.0
blast CAD58749 striatin, calmodulin binding protein 3 [Danio rerio] emb|CAI29388.1| striatin, calmodulin binding protein 3 [Danio rerio] 1.0E-140
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.9E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 9.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 3.0E-11
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.57
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 8.8E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-4
Sequence
Target Sequence 
>C. ELEGANS:174971_AT
ctttccatccttcaagatctcttataggatctgccggtgccgattctcttgccaaggtgt
acgtgtcaggaagcaactagagtatcccattcatttttttattattatttccctattttc
atatttcgccaatttaacttaaagtataataggaattcgccagttcgtctcccagttcat
gcccaaatccacgcctacataccttcatttttattactacaacagtaccctttattttat
tgtagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTTTCCATCCTTCAAGATCTCTTAT 580 223 27 Antisense
ATCTCTTATAGGATCTGCCGGTGCC 279 33 43 Antisense
GGAAGCAACTAGAGTATCCCATTCA 149 529 95 Antisense
GTATCCCATTCATTTTTTTATTATT 176 455 108 Antisense
ATTTCCCTATTTTCATATTTCGCCA 428 17 133 Antisense
CCCTATTTTCATATTTCGCCAATTT 278 257 137 Antisense
TAATAGGAATTCGCCAGTTCGTCTC 17 633 173 Antisense
ACGCCTACATACCTTCATTTTTATT 546 91 217 Antisense
TACCTTCATTTTTATTACTACAACA 209 649 226 Antisense
TATTACTACAACAGTACCCTTTATT 705 657 238 Antisense
CAGTACCCTTTATTTTATTGTAGAT 616 205 249 Antisense
Sequence Source Affymetrix Proprietary Database