[Home] | [Total List]

[174678_at] 2-oxoglutarate dehydrogenase

Description CEK040B2R_rc /REP_DB=TREMBL Accession /GB=D34051 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk40b2 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 53      6grp_high1_10_10 > 25      4grp_highest_8_8 > 35      4grp_high_8_8 > 56      6grp_highest_nonorm > 51      6grp_total > 26      4grp_total > 63      6grp_highest_sub > 02      6grp_high1_sub > 01_02      6grp_total_sub > Cup      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 469
1 2 3 4 range
A 880.5
(3)
P 		470.8
(-3)
P 		748.1
(1.1)
P 		480.4
(-2.9)
P 		410
B 918.2
(3)
P 		621.8
(-3)
P 		744.2
(-0.5)
P 		711.7
(-1.2)
P 		296
C 916.1
(3)
P 		449
(-3)
P 		808.7
(1.6)
P 		506.7
(-2.3)
P 		467
avr 904.9
(3) 		513.9
(-3) 		767
(0.9) 		566.3
(-2.2) 		391

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 533
1 2 3 4 5 6 range
A 675.8
(1.6)
P 		783.3
(3)
P 		372.7
(-2.4)
P 		328.3
(-3)
P 		498
(-0.8)
P 		510.5
(-0.6)
P 		455
B 614.5
(-0.1)
P 		861.2
(3)
P 		390.8
(-3)
P 		561.2
(-0.8)
P 		420.4
(-2.6)
P 		546.3
(-1)
P 		470
C 676.6
(1.1)
P 		800.3
(3)
P 		558.1
(-0.7)
P 		441.8
(-2.5)
P 		414
(-3)
P 		412.6
(-3)
P 		388
avr 655.6
(0.4) 		814.9
(3) 		440.5
(-3) 		443.8
(-2.9) 		444.1
(-2.9) 		489.8
(-2.2) 		374
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 250
1 2 3 4 range
A 320.6
(3)
P 		102.2
(-2.2)
P 		195.6
(0)
P 		70.3
(-3)
P 		250
B 292.8
(3)
P 		153.6
(-2.9)
P 		172.4
(-2.1)
P 		151.7
(-3)
P 		141
C 303.3
(3)
P 		129.1
(-1.8)
P 		281.9
(2.4)
P 		85.4
(-3)
P 		218
avr 305.6
(3) 		128.3
(-2.2) 		216.6
(0.4) 		102.5
(-3) 		203

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 206
1 2 3 4 5 6 range
A 124.6
(-1.7)
P 		278.6
(3)
P 		81.2
(-3)
P 		83.3
(-2.9)
P 		150.3
(-0.9)
P 		124.3
(-1.7)
P 		197
B 213.8
(0.7)
P 		286.7
(3)
P 		94.9
(-3)
P 		148.6
(-1.3)
P 		170.8
(-0.6)
P 		203.7
(0.4)
P 		192
C 250.8
(3)
P 		244.2
(2.8)
P 		142
(-1)
P 		88.8
(-3)
P 		134
(-1.3)
P 		138.1
(-1.2)
P 		162
avr 196.4
(0.3) 		269.8
(3) 		106
(-3) 		106.9
(-3) 		151.7
(-1.3) 		155.4
(-1.2) 		164
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174678_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21864
Sequence Type Exemplar sequence
Representative Public ID CEK040B2R NCBI
Target Description CEK040B2R_rc /REP_DB=TREMBL Accession /GB=D34051 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk40b2 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073659(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073659 NCBI Caenorhabditis elegans ZK836.2 (ZK836.2) mRNA, complete cds. 11/11 A 
ZK836.2.2 ENSEMBL cdna:known chromosome:CEL140:V:12197066:12208073:1 gene:ZK836.2 11/11 A 
ZK836.2.1 ENSEMBL cdna:known chromosome:CEL140:V:12197095:12208089:1 gene:ZK836.2 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000005779 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12207625-12208032(+) 100.0 100.0
Public Domain and Genome References
Gene Title 2-oxoglutarate dehydrogenase
Ensembl ZK836.2
Entrez Gene 179674 Entrez gene
SwissProt Q23629 EMBL-EBI
WormBase CE35706 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1594103_AT similar to dehydrogenase E1 and transketolase domain containing protein 1 cfa
CANINE:1591872_S_AT similar to dehydrogenase E1 and transketolase domain containing protein 1 cfa
CANINE_2:CFA.2905.1.A1_S_AT similar to dehydrogenase E1 and transketolase domain containing protein 1 cfa
DROSOPHILA_2:1641199_A_AT dm
DROSGENOME1:152172_AT dm
HG-U133A:209916_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U133_PLUS_2:209916_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U133A_2:209916_AT dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBA:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBB:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBC:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBD:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HUGENEFL:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HC-G110:HUM_ALU_AT dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBB:RC_W92713_AT dehydrogenase E1 and transketolase domain containing 1 hs
U133_X3P:G12803318_3P_X_AT dehydrogenase E1 and transketolase domain containing 1 hs
U133_X3P:HS.11732.0.A1_3P_AT dehydrogenase E1 and transketolase domain containing 1 hs
U133_X3P:209916_3P_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U133_PLUS_2:227094_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U133B:227094_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U95B:52934_AT dehydrogenase E1 and transketolase domain containing 1 hs
HG-U95B:46796_R_AT Dehydrogenase E1 and transketolase domain containing 1 hs
HU35KSUBD:RC_AA447970_AT Dehydrogenase E1 and transketolase domain containing 1 hs
MOUSE430_2:1457027_AT dehydrogenase E1 and transketolase domain containing 1 mm
MOE430B:1457027_AT dehydrogenase E1 and transketolase domain containing 1 mm
MG-U74BV2:106120_AT dehydrogenase E1 and transketolase domain containing 1 mm
RG-U34C:RC_AI169947_AT dehydrogenase E1 and transketolase domain containing 1 (predicted) rn
RAE230A:1390172_AT dehydrogenase E1 and transketolase domain containing 1 (predicted) rn
RAT230_2:1390172_AT dehydrogenase E1 and transketolase domain containing 1 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01590 Hypothetical protein ZK836.2 [Caenorhabditis elegans] emb|CAE46691.1| Hypothetical protein ZK836.2 [Caenorhabditis elegans] ref|NP_506060.2| ZK836.2 [Caenorhabditis elegans] 0.0
blast CAE75416 Hypothetical protein CBG23406 [Caenorhabditis briggsae] 0.0
blast XP_535192 PREDICTED: similar to dehydrogenase E1 and transketolase domain containing protein 1 [Canis familiaris] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005475 EMBL-EBI Transketolase, central region 1.1E-60
Pfam IPR001017 EMBL-EBI Dehydrogenase, E1 component 1.2E-33
Sequence
Target Sequence 
>C. ELEGANS:174678_AT
gaatgcgttagctcaaatttgccggacgtcccgaacttgcatggaccgctacagcaatcg
gcgaacatcacaccaaagaagccgaggaggtgattaatcaaacgtttgcataagtctcca
gaagaagtctctcttccactttcctcccaccactcttccattttttgttctattccctcc
catccgccccagtctagtagttttgtgcttgtccatttattcttttctagtagattagtt
gtcatttcatacaatggttttgctcaattttcatgtgcatgttctctttcatttgtgatg
ttttgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATGCGTTAGCTCAAATTTGCCGG 155 331 22 Antisense
AAACGTTTGCATAAGTCTCCAGAAG 269 125 121 Antisense
CAGAAGAAGTCTCTCTTCCACTTTC 16 205 140 Antisense
CACTCTTCCATTTTTTGTTCTATTC 54 199 172 Antisense
CCGCCCCAGTCTAGTAGTTTTGTGC 658 261 205 Antisense
AGTTTTGTGCTTGTCCATTTATTCT 142 63 220 Antisense
GCTTGTCCATTTATTCTTTTCTAGT 693 305 228 Antisense
AGTAGATTAGTTGTCATTTCATACA 47 61 250 Antisense
TTTGCTCAATTTTCATGTGCATGTT 210 669 280 Antisense
TCATGTGCATGTTCTCTTTCATTTG 279 623 292 Antisense
TCTCTTTCATTTGTGATGTTTTGTT 337 613 304 Antisense
Sequence Source Affymetrix Proprietary Database