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[174546_at] G-protein coupled receptor

Description C55235_rc /REP_DB=TREMBL Accession /GB=C55235 /CHR=X /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk360g11 : 3prime end, single read.
Cluster 6grp_high1_10_10 > 27      4grp_high_8_8 > 11      6grp_total > 17      4grp_total > 13      6grp_cgc > 12      6grp_high1_sub > Cu      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 256
1 2 3 4 range
A 221.3
(0.6)
P 		97.5
(-3)
P 		186.5
(-0.4)
A 		305.2
(3)
P 		208
B 221.2
(-0)
P 		145.9
(-1.8)
P 		95.6
(-3)
A 		350.6
(3)
P 		255
C 208.3
(0.1)
P 		174.5
(-0.8)
P 		95
(-3)
P 		312
(3)
P 		217
avr 216.9
(-0.2) 		139.3
(-2.6) 		125.7
(-3) 		322.6
(3) 		197

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 217
1 2 3 4 5 6 range
A 279.5
(3)
P 		127.9
(-1.2)
P 		168.3
(-0.1)
P 		62.3
(-3)
A 		108.7
(-1.7)
P 		137.5
(-0.9)
P 		217
B 254.3
(3)
P 		179.7
(0.2)
P 		92.1
(-3)
M 		99.8
(-2.7)
P 		103.7
(-2.6)
P 		132.7
(-1.5)
P 		162
C 184.2
(1.1)
P 		210.8
(3)
P 		154.6
(-1.1)
P 		173.8
(0.3)
P 		128.2
(-3)
P 		143
(-1.9)
P 		83
avr 239.3
(3) 		172.8
(-0.1) 		138.3
(-1.8) 		112
(-3) 		113.5
(-2.9) 		137.7
(-1.8) 		127
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 59
1 2 3 4 range
A 80.6
(3)
P 		21.2
(-3)
P 		48.8
(-0.2)
A 		44.7
(-0.6)
P 		59
B 70.5
(2.5)
P 		36
(-1.4)
P 		22.2
(-3)
A 		74.7
(3)
P 		53
C 68.9
(3)
P 		50.2
(-0.1)
P 		33.1
(-3)
P 		52.6
(0.3)
P 		36
avr 73.3
(3) 		35.8
(-2.8) 		34.7
(-3) 		57.3
(0.5) 		39

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 73
1 2 3 4 5 6 range
A 51.5
(3)
P 		45.5
(2)
P 		36.6
(0.5)
P 		15.8
(-3)
A 		32.8
(-0.1)
P 		33.5
(-0)
P 		36
B 88.5
(3)
P 		59.8
(0.4)
P 		22.4
(-3)
M 		26.4
(-2.6)
P 		42.1
(-1.2)
P 		49.5
(-0.5)
P 		66
C 68.3
(3)
P 		64.3
(2.3)
P 		39.3
(-2.2)
P 		35
(-3)
P 		41.5
(-1.8)
P 		47.9
(-0.7)
P 		33
avr 69.4
(3) 		56.5
(1.2) 		32.8
(-2) 		25.7
(-3) 		38.8
(-1.2) 		43.6
(-0.5) 		44
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174546_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22437
Sequence Type Exemplar sequence
Representative Public ID C55235 NCBI
Target Description C55235_rc /REP_DB=TREMBL Accession /GB=C55235 /CHR=X /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk360g11 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076205(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076205 NCBI Caenorhabditis elegans Unidentified Vitellogenin-linked Transcript family member (uvt-6) (uvt-6) mRNA, complete cds. 11/11 A 
GENEFINDER00000023814 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:3528805:3531683:1 9/11 None
F56B6.5 ENSEMBL cdna:known chromosome:CEL140:X:3528799:3531813:1 gene:F56B6.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:3531550-3531804(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Gene Symbol uvt-6
Ensembl F56B6.5
Entrez Gene 180643 Entrez gene
SwissProt Q22995 EMBL-EBI
WormBase CE31186 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.3154.1.S1_AT somatostatin receptor 3 cfa
CHICKEN:GGAAFFX.23919.1.S1_AT somatostatin receptor 3 gga
CHICKEN:GGA.19891.1.S1_AT Somatostatin receptor 3 gga
HG-U133_PLUS_2:214491_AT somatostatin receptor 3 hs
HG-U133A_2:214491_AT somatostatin receptor 3 hs
HG-FOCUS:214491_AT somatostatin receptor 3 hs
HG-U133A:214491_AT somatostatin receptor 3 hs
HG-U95AV2:557_S_AT somatostatin receptor 3 hs
HC-G110:557_S_AT somatostatin receptor 3 hs
HUGENEFL:Z86000_AT somatostatin receptor 3 hs
HUGENEFL:M96738_S_AT somatostatin receptor 3 hs
U133_X3P:HS2.225995.1.S1_3P_S_AT somatostatin receptor 3 hs
U133_X3P:HS.225995.0.S1_3P_AT somatostatin receptor 3 hs
HG-U133_PLUS_2:1553178_A_AT somatostatin receptor 3 hs
MOE430A:1450577_AT somatostatin receptor 3 mm
MOUSE430_2:1450577_AT somatostatin receptor 3 mm
MOUSE430A_2:1450577_AT somatostatin receptor 3 mm
MU11KSUBB:MSA.1187.0_AT somatostatin receptor 3 mm
MG-U74AV2:101309_AT somatostatin receptor 3 mm
MOE430B:1441603_AT Somatostatin receptor 3 (Sstr3), mRNA mm
MOUSE430_2:1441603_AT Somatostatin receptor 3 (Sstr3), mRNA mm
RAE230A:1368598_AT hypothetical gene supported by NM_133522 rn
RAT230_2:1368598_AT hypothetical gene supported by NM_133522 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB04560 Unidentified vitellogenin-linked transcript protein 6 [Caenorhabditis elegans] ref|NP_508606.2| Unidentified Vitellogenin-linked Transcript family member (uvt-6) [Caenorhabditis elegans] 0.0
blast CAE68442 Hypothetical protein CBG14230 [Caenorhabditis briggsae] 0.0
blast EAA03588 ENSANGP00000018071 [Anopheles gambiae str. PEST] ref|XP_307800.2| ENSANGP00000018071 [Anopheles gambiae str. PEST] 2.0E-32
blast AAF98367 somatostatin receptor type two [Carassius auratus] 4.0E-32
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.7E-50
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508606.2 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
F56B6.5 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
GENEFINDER00000023814 7 10-32,45-67,82-104,125-147,182-204,240-262,272-294
Sequence
Target Sequence 
>C. ELEGANS:174546_AT
acttcaagcctggcggccttatgatggaactaactgtgaagtattagaagttcaatacga
tcatcataaatgctccgccagaagtatccttctcccagctgtcacagtggacgaaggaac
aaaattatgatgatgaaaactttgaaaataaattataggaacgtgtcgcattgtctcttg
cacacttccgggtacgcatctttcctcccgatgagaaatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACTTCAAGCCTGGCGGCCTTATGAT 138 103 17 Antisense
AGCCTGGCGGCCTTATGATGGAACT 11 83 23 Antisense
GGCGGCCTTATGATGGAACTAACTG 599 539 28 Antisense
GGCCTTATGATGGAACTAACTGTGA 660 541 31 Antisense
TTAGAAGTTCAATACGATCATCATA 626 681 60 Antisense
ACGATCATCATAAATGCTCCGCCAG 78 95 73 Antisense
TAAATGCTCCGCCAGAAGTATCCTT 120 641 83 Antisense
TTCTCCCAGCTGTCACAGTGGACGA 609 691 106 Antisense
CAGCTGTCACAGTGGACGAAGGAAC 329 203 112 Antisense
TAGGAACGTGTCGCATTGTCTCTTG 316 653 172 Antisense
GCATCTTTCCTCCCGATGAGAAATC 404 309 212 Antisense
Sequence Source Affymetrix Proprietary Database