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[174493_at] GTP-binding protein

Description C58111_rc /REP_DB=TREMBL Accession /GB=C58111 /CHR=X /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk361d11 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 05      4grp_highest_8_8 > 52      4grp_high_8_8 > 25      6grp_highest_nonorm > 90      6grp_total > 06      4grp_total > 39      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 215
1 2 3 4 range
A 246
(3)
P 		102.4
(-2.3)
P 		83.3
(-3)
P 		113.6
(-1.9)
P 		163
B 246.7
(3)
P 		70.9
(-3)
P 		78.2
(-2.8)
P 		119.9
(-1.3)
P 		176
C 282.1
(3)
P 		115.7
(-1.6)
P 		67.2
(-3)
P 		187.2
(0.4)
P 		215
avr 258.3
(3) 		96.3
(-2.3) 		76.2
(-3) 		140.2
(-0.9) 		182

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 255
1 2 3 4 5 6 range
A 316.7
(3)
P 		136.4
(-1.4)
P 		146.8
(-1.1)
P 		88.5
(-2.5)
P 		101.3
(-2.2)
P 		68.2
(-3)
P 		249
B 221
(3)
P 		196.3
(1.9)
P 		119.5
(-1.5)
P 		87.8
(-3)
P 		102.4
(-2.3)
P 		86.8
(-3)
P 		134
C 204.8
(2.8)
P 		208.7
(3)
P 		127.2
(-0.3)
P 		111.2
(-1)
P 		81.4
(-2.2)
P 		61.4
(-3)
P 		147
avr 247.5
(3) 		180.5
(0.7) 		131.2
(-1) 		95.8
(-2.2) 		95
(-2.2) 		72.1
(-3) 		175
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 77
1 2 3 4 range
A 89.6
(3)
P 		22.2
(-2.5)
P 		21.8
(-2.6)
P 		16.6
(-3)
P 		73
B 78.7
(3)
P 		17.5
(-3)
P 		18.1
(-2.9)
P 		25.5
(-2.2)
P 		61
C 93.4
(3)
P 		33.3
(-2.2)
P 		23.4
(-3)
P 		31.6
(-2.3)
P 		70
avr 87.2
(3) 		24.3
(-2.7) 		21.1
(-3) 		24.6
(-2.7) 		66

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 58.4
(3)
P 		48.5
(1.6)
P 		32
(-0.8)
P 		22.4
(-2.2)
P 		30.6
(-1)
P 		16.6
(-3)
P 		42
B 76.9
(3)
P 		65.3
(1.7)
P 		29
(-2.4)
P 		23.3
(-3)
P 		41.6
(-1)
P 		32.4
(-2)
P 		54
C 75.9
(3)
P 		63.7
(1.7)
P 		32.4
(-1.7)
P 		22.4
(-2.8)
P 		26.3
(-2.4)
P 		20.5
(-3)
P 		55
avr 70.4
(3) 		59.2
(1.6) 		31.1
(-1.9) 		22.7
(-3) 		32.8
(-1.7) 		23.2
(-2.9) 		48
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174493_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22143
Sequence Type Exemplar sequence
Representative Public ID C58111 NCBI
Target Description C58111_rc /REP_DB=TREMBL Accession /GB=C58111 /CHR=X /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk361d11 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076320(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076320 NCBI Caenorhabditis elegans RAB family member (rab-37) (rab-37) mRNA, complete cds. 11/11 None
W01H2.3 ENSEMBL cdna:known chromosome:CEL140:X:4227831:4231196:-1 gene:W01H2.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:4228187-4228467(-) 100.0 100.0
Public Domain and Genome References
Gene Title GTP-binding protein
Gene Symbol rab-37
Ensembl W01H2.3
Entrez Gene 180696 Entrez gene
SwissProt O02046 EMBL-EBI
WormBase CE07562 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.7823.1.S1_AT similar to Ras-related protein Rab-37 cfa
CANINE_2:CFAAFFX.7826.1.S1_AT similar to Ras-related protein Rab-37 cfa
CANINE_2:CFAAFFX.7826.1.S1_S_AT similar to Ras-related protein Rab-37 cfa
DROSOPHILA_2:1623233_AT dm
DROSGENOME1:152856_AT dm
HU35KSUBB:RC_R62453_AT RAB37, member RAS oncogene family hs
U133_X3P:HS.321677.1.S1_3P_AT RAB37, member RAS oncogene family hs
HG-U133_PLUS_2:228113_AT RAB37, member RAS oncogene family hs
HG-U133B:228113_AT RAB37, member RAS oncogene family hs
HG-U95B:47429_AT RAB37, member RAS oncogene family hs
HG-U95D:84874_AT RAB37, member RAS oncogene family hs
U133_X3P:HS.147066.0.A1_3P_AT RAB37, member RAS oncogene family hs
MOUSE430_2:1450167_AT RAB37, member of RAS oncogene family mm
MOE430A:1450167_AT RAB37, member of RAS oncogene family mm
MOUSE430A_2:1450167_AT RAB37, member of RAS oncogene family mm
MG-U74CV2:139223_AT RAB37, member of RAS oncogene family mm
MOE430B:1433947_AT RAB37, member of RAS oncogene family mm
MOUSE430_2:1433947_AT RAB37, member of RAS oncogene family mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
7264 small GTPase mediated signal transduction inferred from electronic annotation QuickGO AmiGO
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52888 Rab family protein 37 [Caenorhabditis elegans] ref|NP_508721.1| RAB family member (rab-37) [Caenorhabditis elegans] dbj|BAD32698.1| Rab37 [Caenorhabditis elegans] 1.0E-110
blast CAE68542 Hypothetical protein CBG14372 [Caenorhabditis briggsae] 5.0E-89
blast XP_540417 PREDICTED: similar to Ras-related protein Rab-37 [Canis familiaris] 8.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR001806 EMBL-EBI Ras GTPase superfamily 5.7E-82
Sequence
Target Sequence 
>C. ELEGANS:174493_AT
catttattttaaactctcatccacgaatctctccctgttagtgcaatttctgtgatctca
ttctgagtgtattgatccgatgaaaaacaaatattctcatctggtggccgagtcaaaatg
gtttttaaaaaactctagaaaaacctatattatttttgaattaggaatcatgtaccagtg
gcaaaactcagactattctgtaaatttca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATTTATTTTAAACTCTCATCCACG 434 215 41 Antisense
TTATTTTAAACTCTCATCCACGAAT 228 677 44 Antisense
TCTCTCCCTGTTAGTGCAATTTCTG 194 613 68 Antisense
GTTAGTGCAATTTCTGTGATCTCAT 40 447 77 Antisense
GCAATTTCTGTGATCTCATTCTGAG 443 323 83 Antisense
ATCTCATTCTGAGTGTATTGATCCG 544 31 95 Antisense
TCTGAGTGTATTGATCCGATGAAAA 341 607 102 Antisense
AAACAAATATTCTCATCTGGTGGCC 380 129 125 Antisense
GAATTAGGAATCATGTACCAGTGGC 386 325 198 Antisense
GTACCAGTGGCAAAACTCAGACTAT 20 459 212 Antisense
AACTCAGACTATTCTGTAAATTTCA 546 137 225 Antisense
Sequence Source Affymetrix Proprietary Database