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[174412_at] guanine nucleotide-binding protein

Description C37415_rc /REP_DB=TREMBL Accession /GB=C37415 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk473e6 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 63      6grp_high1_10_10 > 36      4grp_highest_8_8 > 50      4grp_high_8_8 > 33      6grp_highest_nonorm > 03      6grp_total > 36      4grp_total > 46      6grp_highest_sub > Cu      6grp_cgc > 15      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2218
1 2 3 4 range
A 4617.8
(3)
P 		3185.2
(-1.3)
P 		2937.2
(-2.1)
P 		2626.2
(-3)
P 		1992
B 4404
(3)
P 		2995.6
(-2)
P 		2721.9
(-3)
P 		2947.8
(-2.2)
P 		1682
C 3770.4
(3)
P 		2799.5
(-1.3)
P 		2702.1
(-1.7)
P 		2400.1
(-3)
P 		1370
avr 4264.1
(3) 		2993.4
(-1.7) 		2787.1
(-2.5) 		2658
(-3) 		1606

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1765
1 2 3 4 5 6 range
A 4066.1
(3)
P 		3406.9
(0.7)
P 		3256.1
(0.2)
P 		2423.4
(-2.7)
P 		2448.5
(-2.6)
P 		2340.7
(-3)
P 		1725
B 3673.9
(2.6)
P 		3760.5
(3)
P 		3055.7
(0.1)
P 		2600.9
(-1.8)
P 		2301.1
(-3)
P 		3477.8
(1.8)
P 		1459
C 3652.9
(2.7)
P 		3716.8
(3)
P 		2687.9
(-1.6)
P 		2456.6
(-2.6)
P 		2366.9
(-3)
P 		3430.1
(1.7)
P 		1350
avr 3797.6
(3) 		3628.1
(2.3) 		2999.9
(-0.4) 		2493.6
(-2.5) 		2372.2
(-3) 		3082.9
(-0) 		1425
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1297
1 2 3 4 range
A 1681.3
(3)
P 		691.4
(-1.6)
P 		767.8
(-1.2)
P 		384.4
(-3)
P 		1297
B 1404.4
(3)
P 		739.8
(-2.1)
P 		630.7
(-3)
P 		628.2
(-3)
P 		776
C 1248.1
(3)
P 		804.9
(-0.2)
P 		941.8
(0.8)
P 		404.7
(-3)
P 		843
avr 1444.6
(3) 		745.4
(-1.3) 		780.1
(-1.1) 		472.4
(-3) 		972

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 860
1 2 3 4 5 6 range
A 749.6
(-1.3)
P 		1211.7
(3)
P 		709.1
(-1.7)
P 		614.6
(-2.6)
P 		738.9
(-1.4)
P 		569.9
(-3)
P 		642
B 1278.3
(2.8)
P 		1251.7
(2.6)
P 		742
(-2.5)
P 		688.9
(-3)
P 		934.9
(-0.6)
P 		1296.9
(3)
P 		608
C 1354
(3)
P 		1134.1
(1.5)
P 		684.1
(-1.7)
P 		494
(-3)
P 		765.9
(-1.1)
P 		1148.3
(1.6)
P 		860
avr 1127.3
(2.3) 		1199.2
(3) 		711.7
(-1.9) 		599.2
(-3) 		813.2
(-0.9) 		1005
(1.1) 		600
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174412_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20413
Sequence Type Exemplar sequence
Representative Public ID C37415 NCBI
Target Description C37415_rc /REP_DB=TREMBL Accession /GB=C37415 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk473e6 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059707(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059707 NCBI Caenorhabditis elegans G protein,O, Alpha subunit family member (goa-1) (goa-1) mRNA, complete cds. 11/11 A 
C26C6.2 ENSEMBL cdna:known chromosome:CEL140:I:7530244:7534842:1 gene:C26C6.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7534406-7534738(+) 80.12 100.0
Public Domain and Genome References
Gene Title guanine nucleotide-binding protein
Gene Symbol goa-1
Ensembl C26C6.2
Entrez Gene 172505 Entrez gene
SwissProt P51875 EMBL-EBI
WormBase CE05311 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.19360.1.S1_S_AT similar to Guanine nucleotide-binding protein G(o), alpha subunit 2 cfa
CANINE_2:CFAAFFX.14666.1.S1_AT similar to Guanine nucleotide-binding protein G(o), alpha subunit 2 cfa
DROSGENOME1:142441_AT G protein o 47A dm
DROSOPHILA_2:1632830_S_AT G protein o 47A dm
DROSGENOME1:151572_R_AT G protein o 47A dm
CHICKEN:GGAAFFX.25767.1.S1_AT similar to guanine nucleotide binding protein alpha oB gga
HG-U95AV2:34698_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95AV2:236_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HC-G110:236_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:204763_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:215912_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HU35KSUBD:RC_N80889_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HUGENEFL:M60165_CDS1_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:231951_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133B:231951_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:G10567815_3P_A_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.0.S1_3P_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.0.S1_3P_A_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.296184.1.S1_3P_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.198511.0.S1_3P_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A_2:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-FOCUS:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133A:204762_S_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95AV2:34138_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95E:69489_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95E:90648_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:91782_F_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:91785_R_AT guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133B:240328_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U133_PLUS_2:240328_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
U133_X3P:HS.150495.0.A1_3P_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
HG-U95D:80689_AT Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O hs
MG-U74AV2:103844_AT guanine nucleotide binding protein, alpha o mm
MOUSE430_2:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOE430A:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOUSE430A_2:1421152_A_AT guanine nucleotide binding protein, alpha o mm
MOUSE430A_2:1460383_AT guanine nucleotide binding protein, alpha o mm
MOUSE430_2:1460383_AT guanine nucleotide binding protein, alpha o mm
MOE430A:1460383_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBA:M36778_S_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBB:MSA.663.0_R_AT guanine nucleotide binding protein, alpha o mm
MU11KSUBB:MSA.663.0_S_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:100388_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:103843_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:161902_F_AT guanine nucleotide binding protein, alpha o mm
MG-U74AV2:104414_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU11KSUBA:AA231554_F_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBA:TC18252_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBA:TC18252_G_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBB:TC28053_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
MU19KSUBC:TC41585_S_AT Guanine nucleotide binding protein, alpha o (Gnao1), mRNA mm
RN-U34:M17526_G_AT guanine nucleotide binding protein, alpha o rn
RG-U34A:M17526_G_AT guanine nucleotide binding protein, alpha o rn
RN-U34:M17526_AT guanine nucleotide binding protein, alpha o rn
RG-U34A:M17526_AT guanine nucleotide binding protein, alpha o rn
RG-U34C:RC_AI227704_AT guanine nucleotide binding protein, alpha o rn
RAE230A:1368879_A_AT guanine nucleotide binding protein, alpha o rn
RAT230_2:1368879_A_AT guanine nucleotide binding protein, alpha o rn
RAE230A:1374314_AT Guanine nucleotide binding protein, alpha o rn
RAT230_2:1374314_AT Guanine nucleotide binding protein, alpha o rn
RG-U34B:RC_AA963891_AT Guanine nucleotide binding protein, alpha o rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
5525 GTP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA96595 Hypothetical protein C26C6.2 [Caenorhabditis elegans] ref|NP_492108.1| G protein,O, Alpha subunit family member (goa-1) [Caenorhabditis elegans] gb|AAG32093.1| heterotrimeric G protein alpha subunit [Caenorhabditis elegans] sp|P51875|GNAO_CAEEL Guanine nucleotide-binding protein G(o), alpha subunit 0.0
blast AAA28059 G-o protein alpha subunit 0.0
blast AAW02892 goa-1 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001019 EMBL-EBI Guanine nucleotide binding protein (G-protein), alpha subunit 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:174412_AT
tcccatttttcaacacacctagtcactgttaacagttaaataatggcagcttttgtctat
gtttaaagattttatttttaatttttggtatttttctatttctactcttcccctctcatc
cattttccctccttttcctaaaaccacacttccaaactcatttttctcgctgttttcctc
tccctattttttcttttactttttcatttttccatcttttttctttaaaatcgtctcgct
ttttgtcggtgagcacgatggtgtgcagtagacgatattttccgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCCATTTTTCAACACACCTAGTCA 61 599 30 Antisense
CATTTTTCAACACACCTAGTCACTG 125 215 33 Antisense
ACACACCTAGTCACTGTTAACAGTT 88 111 42 Antisense
AATAATGGCAGCTTTTGTCTATGTT 69 173 68 Antisense
ATGGCAGCTTTTGTCTATGTTTAAA 236 51 72 Antisense
TGGTATTTTTCTATTTCTACTCTTC 666 551 115 Antisense
TAAAATCGTCTCGCTTTTTGTCGGT 568 627 255 Antisense
TCGTCTCGCTTTTTGTCGGTGAGCA 600 603 260 Antisense
CTCGCTTTTTGTCGGTGAGCACGAT 575 233 264 Antisense
GTCGGTGAGCACGATGGTGTGCAGT 218 473 274 Antisense
GTGTGCAGTAGACGATATTTTCCGC 454 487 290 Antisense
Sequence Source Affymetrix Proprietary Database