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[174187_s_at] protein-tyrosine phosphatase

Description C51741_rc /REP_DB=TREMBL Accession /GB=C51741 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk214a3 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 53      6grp_high1_10_10 > 35      4grp_highest_8_8 > 54      4grp_high_8_8 > 18      6grp_highest_nonorm > 61      6grp_total > 35      4grp_total > 22      6grp_highest_sub > 02      6grp_high1_sub > 02      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 463
1 2 3 4 range
A 667.9
(3)
P 		338
(-1.3)
P 		205.2
(-3)
P 		490.6
(0.7)
P 		463
B 500.4
(2)
P 		318.4
(-1.1)
P 		206
(-3)
P 		557.3
(3)
P 		351
C 609.8
(3)
P 		253.7
(-3)
P 		281.4
(-2.5)
P 		511.1
(1.3)
P 		356
avr 592.7
(3) 		303.4
(-1.8) 		230.9
(-3) 		519.7
(1.8) 		362

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 405
1 2 3 4 5 6 range
A 578
(2.8)
P 		589.8
(3)
P 		501.7
(1.3)
P 		362.3
(-1.4)
P 		277.8
(-3)
P 		338.2
(-1.8)
P 		312
B 491.1
(0.2)
P 		663.5
(3)
P 		437.8
(-0.7)
P 		300.2
(-3)
P 		304.7
(-2.9)
P 		446.1
(-0.6)
P 		363
C 515.1
(0.7)
P 		673.1
(3)
P 		296.9
(-2.6)
P 		280.7
(-2.8)
P 		268.4
(-3)
P 		422.8
(-0.7)
P 		405
avr 528.1
(1.1) 		642.1
(3) 		412.1
(-0.8) 		314.4
(-2.5) 		283.6
(-3) 		402.4
(-1) 		359
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 196
1 2 3 4 range
A 243.2
(3)
P 		73.4
(-2.4)
P 		53.6
(-3)
P 		71.8
(-2.4)
P 		190
B 159.6
(3)
P 		78.6
(-1.3)
P 		47.7
(-3)
P 		118.8
(0.8)
P 		112
C 201.9
(3)
P 		72.9
(-3)
P 		98.1
(-1.8)
P 		86.2
(-2.4)
P 		129
avr 201.6
(3) 		75
(-2.6) 		66.5
(-3) 		92.3
(-1.9) 		135

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 165
1 2 3 4 5 6 range
A 106.5
(-1.9)
P 		209.8
(3)
P 		109.3
(-1.7)
P 		91.9
(-2.5)
P 		83.8
(-2.9)
P 		82.3
(-3)
P 		128
B 170.9
(0.9)
P 		220.9
(3)
P 		106.3
(-1.9)
P 		79.5
(-3)
P 		123.8
(-1.1)
P 		166.4
(0.7)
P 		141
C 190.9
(2.4)
P 		205.4
(3)
P 		75.6
(-2.2)
P 		56.4
(-3)
P 		86.8
(-1.8)
P 		141.5
(0.4)
P 		149
avr 156.1
(0.5) 		212
(3) 		97.1
(-2.1) 		75.9
(-3) 		98.1
(-2) 		130.1
(-0.6) 		136
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 174187_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21474
Sequence Type Exemplar sequence
Representative Public ID C51741 NCBI
Target Description C51741_rc /REP_DB=TREMBL Accession /GB=C51741 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk214a3 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069462(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069462 NCBI Caenorhabditis elegans K04D7.4 (K04D7.4) mRNA, complete cds. 11/11 A 
SNAP00000009543 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10183921:10188409:-1 11/11 None
GENEFINDER00000009552 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10183921:10193336:-1 11/11 None
K04D7.4 ENSEMBL cdna:known chromosome:CEL140:IV:10183883:10192036:-1 gene:K04D7.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10183897-10184176(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl K04D7.4
Entrez Gene 177898 Entrez gene
SwissProt P28192 EMBL-EBI
WormBase CE06093 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93513 Hypothetical protein K04D7.4 [Caenorhabditis elegans] ref|NP_501863.1| K04D7.4 [Caenorhabditis elegans] sp|P28192|PTP2_CAEEL Tyrosine-protein phosphatase 2 (Protein-tyrosine phosphatase 2) 0.0
blast CAE59914 Hypothetical protein CBG03399 [Caenorhabditis briggsae] 0.0
blast AAF56891 CG2005-PA, isoform A [Drosophila melanogaster] ref|NP_733288.1| CG2005-PA, isoform A [Drosophila melanogaster] 2.0E-78
Protein Domains
Database ID Description E-Value
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.2E-14
Pfam IPR003961 EMBL-EBI Fibronectin, type III 7.0E-6
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.3E-9
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.5E-101
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.8E-6
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.2E-14
Pfam IPR003961 EMBL-EBI Fibronectin, type III 7.0E-6
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.3E-9
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.5E-101
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.2E-14
Pfam IPR003961 EMBL-EBI Fibronectin, type III 7.0E-6
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.3E-9
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.5E-101
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.1E-4
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501863.1 1 579-601
K04D7.4 1 579-601
SNAP00000009543 1 429-451
GENEFINDER00000009552 1 518-540
Sequence
Target Sequence 
>C. ELEGANS:174187_S_AT
gatgatacagcacttgcattcagtatttgtgcagccacaactttagcgtgtcaactggag
acaacgggttgtgttgacgtggtacaggttctttcatcgtataccgaaattcagtgtggt
atttttgcctcgaaggtgaaaatcgaattatctcattttccaataccaaattattttgtt
ttcagcaagaaatcgagataatctatgaaaagatgtcacagctagtcggaggaacac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATGATACAGCACTTGCATTCAGTA 233 411 18 Antisense
GCATTCAGTATTTGTGCAGCCACAA 216 307 33 Antisense
GCAGCCACAACTTTAGCGTGTCAAC 649 313 48 Antisense
GCGTGTCAACTGGAGACAACGGGTT 227 285 63 Antisense
ACGGGTTGTGTTGACGTGGTACAGG 602 93 81 Antisense
GACGTGGTACAGGTTCTTTCATCGT 629 377 93 Antisense
ACAGGTTCTTTCATCGTATACCGAA 360 95 101 Antisense
ATCGTATACCGAAATTCAGTGTGGT 331 35 113 Antisense
TCAGTGTGGTATTTTTGCCTCGAAG 393 623 128 Antisense
AAAGATGTCACAGCTAGTCGGAGGA 21 121 226 Antisense
ATGTCACAGCTAGTCGGAGGAACAC 705 45 230 Antisense
Sequence Source Affymetrix Proprietary Database