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[174174_at] mitochondrial carrier protein

Description C32464_rc /REP_DB=TREMBL Accession /GB=C32464 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk331b9 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 02      4grp_highest_8_8 > 43      4grp_high_8_8 > 40      6grp_highest_nonorm > 71      6grp_total > 24      4grp_total > 55      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 205
1 2 3 4 range
A 431.3
(3)
P 		226.7
(-3)
P 		308.9
(-0.6)
P 		264.4
(-1.9)
P 		205
B 369
(3)
P 		281.1
(-0.9)
P 		258.1
(-2)
P 		235.1
(-3)
P 		134
C 352.7
(3)
P 		245.6
(-2.6)
P 		252.3
(-2.2)
P 		237.8
(-3)
P 		115
avr 384.3
(3) 		251.1
(-2.8) 		273.1
(-1.8) 		245.8
(-3) 		139

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 224
1 2 3 4 5 6 range
A 436.1
(3)
P 		308.8
(-3)
P 		423.4
(2.4)
P 		314.5
(-2.7)
P 		315.3
(-2.7)
P 		308
(-3)
P 		128
B 361.3
(3)
P 		307
(-0.6)
P 		272
(-3)
P 		337.6
(1.4)
P 		308.5
(-0.5)
P 		360.5
(2.9)
P 		89
C 279.9
(-1.1)
P 		431.9
(3)
P 		325
(0.1)
P 		307.2
(-0.4)
P 		212
(-3)
P 		246.6
(-2.1)
P 		220
avr 359.1
(3) 		349.2
(2.3) 		340.1
(1.6) 		319.8
(0.1) 		278.6
(-3) 		305
(-1) 		81
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 118
1 2 3 4 range
A 157
(3)
P 		49.2
(-2.5)
P 		80.7
(-0.9)
P 		38.7
(-3)
P 		118
B 117.7
(3)
P 		69.4
(-1.3)
P 		59.8
(-2.1)
P 		50.1
(-3)
P 		68
C 116.8
(3)
P 		70.6
(-0.6)
P 		87.9
(0.7)
P 		40.1
(-3)
P 		77
avr 130.5
(3) 		63.1
(-1.6) 		76.1
(-0.7) 		43
(-3) 		88

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 73
1 2 3 4 5 6 range
A 80.4
(-2.1)
P 		109.8
(3)
P 		92.2
(-0)
P 		79.8
(-2.2)
P 		95.1
(0.5)
P 		75
(-3)
P 		35
B 125.7
(2.2)
P 		102.2
(0.2)
P 		66.1
(-3)
P 		89.4
(-1)
P 		125.3
(2.2)
P 		134.4
(3)
P 		68
C 103.8
(0.6)
P 		131.8
(3)
P 		82.7
(-1.2)
P 		61.8
(-3)
P 		68.6
(-2.4)
P 		82.5
(-1.2)
P 		70
avr 103.3
(1.2) 		114.6
(3) 		80.3
(-2.5) 		77
(-3) 		96.3
(0.1) 		97.3
(0.2) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174174_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21466
Sequence Type Exemplar sequence
Representative Public ID C32464 NCBI
Target Description C32464_rc /REP_DB=TREMBL Accession /GB=C32464 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk331b9 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069151(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069151 NCBI Caenorhabditis elegans D1046.3 (D1046.3) mRNA, complete cds. 11/11 None
D1046.3 ENSEMBL cdna:known chromosome:CEL140:IV:8930424:8932705:1 gene:D1046.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:8932421-8932701(+) 100.0 100.0
Public Domain and Genome References
Gene Title mitochondrial carrier protein
Ensembl D1046.3
Entrez Gene 177711 Entrez gene
SwissProt Q18934 EMBL-EBI
WormBase CE03096 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:252878_AT mitochondrial substrate carrier family protein at
CANINE:1603896_S_AT similar to solute carrier family 25, member 26 isoform a cfa
CANINE:1602405_AT similar to solute carrier family 25, member 26 isoform a cfa
CANINE_2:CFA.8566.1.S1_AT similar to solute carrier family 25, member 26 isoform a cfa
CANINE_2:CFA.8566.2.S1_AT similar to solute carrier family 25, member 26 isoform a cfa
CANINE_2:CFAAFFX.10960.1.S1_S_AT similar to solute carrier family 25, member 26 isoform a cfa
DROSOPHILA_2:1626701_AT dm
DROSGENOME1:150602_AT dm
CHICKEN:GGA.11135.2.S1_A_AT solute carrier family 25, member 26 gga
MOUSE430_2:1428929_S_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOE430A:1428929_S_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOUSE430A_2:1428929_S_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MG-U74BV2:111207_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOE430A:1453886_A_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOUSE430A_2:1453886_A_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOUSE430_2:1453886_A_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 mm
MOE430B:1457540_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26, mRNA (cDNA clone MGC:46774 IMAGE:5026631) mm
MOUSE430_2:1457540_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26, mRNA (cDNA clone MGC:46774 IMAGE:5026631) mm
RAE230A:1374652_AT Solute carrier family 25, member 26 (predicted) rn
RAT230_2:1374652_AT Solute carrier family 25, member 26 (predicted) rn
YEAST_2:1775712_AT S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92291 Hypothetical protein D1046.3 [Caenorhabditis elegans] ref|NP_501552.1| D1046.3 [Caenorhabditis elegans] 1.0E-151
blast CAE74071 Hypothetical protein CBG21724 [Caenorhabditis briggsae] 1.0E-137
blast AAH96793 Hypothetical protein LOC560478 [Danio rerio] ref|NP_001025314.1| hypothetical protein LOC560478 [Danio rerio] 3.0E-61
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.3E-12
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.0E-11
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.7E-27
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501552.1 3 7-29,51-73,235-257
D1046.3 3 7-29,51-73,235-257
Sequence
Target Sequence 
>C. ELEGANS:174174_AT
ttttcctcccaatactttctgaacacataccacatcactcaaattgttctttttcctcca
tttttcttccgacttttgattgttttcccttcatatcttttgataaaatccatttttgca
gaaaactgattttcggtttctgcacaaaaatagtttcagaatattgaaaacgactagtct
attcatatagatgttctctttttttcagattatataggaccagtttttggattgatgact
ttgtccccct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTTCCTCCCAATACTTTCTGAACA 223 673 13 Antisense
ATACTTTCTGAACACATACCACATC 696 23 24 Antisense
AACACATACCACATCACTCAAATTG 536 135 34 Antisense
TCAAATTGTTCTTTTTCCTCCATTT 299 629 51 Antisense
CGACTTTTGATTGTTTTCCCTTCAT 310 205 82 Antisense
GTTTTCCCTTCATATCTTTTGATAA 146 449 94 Antisense
AACTGATTTTCGGTTTCTGCACAAA 250 143 136 Antisense
GAAAACGACTAGTCTATTCATATAG 28 355 178 Antisense
ATAGATGTTCTCTTTTTTTCAGATT 217 23 199 Antisense
AGATTATATAGGACCAGTTTTTGGA 311 43 219 Antisense
TTTGGATTGATGACTTTGTCCCCCT 213 667 238 Antisense
Sequence Source Affymetrix Proprietary Database