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[174108_s_at] C2 domain protein

Description C57758 /REP_DB=TREMBL Accession /GB=C57758 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk298c10 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 31      6grp_high1_10_10 > 03      4grp_highest_8_8 > 61      4grp_high_8_8 > 17      6grp_highest_nonorm > 41      6grp_total > 24      4grp_total > 30      6grp_highest_sub > De      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1080
1 2 3 4 range
A 1473.7
(3)
P 		736.3
(-1.6)
P 		520
(-3)
P 		1114.1
(0.7)
P 		954
B 1556
(3)
P 		649.1
(-2)
P 		476
(-3)
P 		1216.7
(1.1)
P 		1080
C 1469.3
(3)
P 		755.1
(-1.4)
P 		494
(-3)
P 		1164
(1.1)
P 		975
avr 1499.7
(3) 		713.5
(-1.7) 		496.7
(-3) 		1164.9
(1) 		1003

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 578
1 2 3 4 5 6 range
A 738.1
(0.6)
P 		896.4
(3)
P 		623.2
(-1.1)
P 		648.8
(-0.7)
P 		493.4
(-3)
P 		651.8
(-0.6)
P 		403
B 977.6
(3)
P 		793.5
(0.7)
P 		811.7
(0.9)
P 		602.6
(-1.6)
P 		492.3
(-3)
P 		519
(-2.7)
P 		485
C 1069.8
(3)
P 		837.5
(0.6)
P 		727.9
(-0.6)
P 		706.2
(-0.8)
P 		546.6
(-2.5)
P 		498.5
(-3)
P 		571
avr 928.5
(3) 		842.5
(1.8) 		720.9
(0) 		652.5
(-1) 		510.8
(-3) 		556.4
(-2.3) 		418
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 426
1 2 3 4 range
A 536.6
(3)
P 		159.8
(-2.6)
P 		135.9
(-3)
P 		163.1
(-2.6)
P 		401
B 496.2
(3)
P 		160.3
(-2.2)
P 		110.3
(-3)
P 		259.3
(-0.7)
P 		386
C 486.4
(3)
P 		217.1
(-2.1)
P 		172.2
(-3)
P 		196.3
(-2.5)
P 		314
avr 506.4
(3) 		179.1
(-2.4) 		139.5
(-3) 		206.2
(-1.9) 		367

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 261
1 2 3 4 5 6 range
A 136.1
(-3)
P 		318.8
(3)
P 		135.7
(-3)
P 		164.6
(-2.1)
P 		148.9
(-2.6)
P 		158.7
(-2.2)
P 		183
B 340.1
(3)
P 		264.1
(0.5)
P 		197.1
(-1.8)
P 		159.6
(-3)
P 		200
(-1.7)
P 		193.5
(-1.9)
P 		181
C 396.5
(3)
P 		255.5
(-0.3)
P 		185.3
(-2)
P 		142
(-3)
P 		176.9
(-2.2)
P 		166.9
(-2.4)
P 		255
avr 290.9
(3) 		279.5
(2.5) 		172.7
(-2.2) 		155.4
(-3) 		175.3
(-2.1) 		173
(-2.2) 		136
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 174108_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20421
Sequence Type Exemplar sequence
Representative Public ID C57758 NCBI
Target Description C57758 /REP_DB=TREMBL Accession /GB=C57758 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk298c10 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059452(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059452 NCBI Caenorhabditis elegans SyNapTotagmin family member (snt-4) (snt-4) mRNA, complete cds. 11/11 A 
SNAP00000032983 ENSEMBL cdna:SNAP chromosome:CEL140:I:6444207:6449032:1 11/11 None
GENEFINDER00000032992 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6444286:6449032:1 11/11 None
T23H2.2 ENSEMBL cdna:known chromosome:CEL140:I:6444286:6449032:1 gene:T23H2.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6444192-6446729(+) 100.0 100.0
Public Domain and Genome References
Gene Title C2 domain protein
Gene Symbol snt-4
Ensembl T23H2.2
Entrez Gene 172346 Entrez gene
SwissProt P91493 EMBL-EBI
WormBase CE30456 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM15607 Synaptotagmin protein 4 [Caenorhabditis elegans] ref|NP_491853.2| SyNapTotagmin family member (snt-4) [Caenorhabditis elegans] 0.0
blast CAE67192 Hypothetical protein CBG12628 [Caenorhabditis briggsae] 0.0
blast T28967 hypothetical protein T23H2.2 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000008 EMBL-EBI C2 domain 3.2E-24
Pfam IPR000008 EMBL-EBI C2 domain 5.8E-30
Pfam IPR000008 EMBL-EBI C2 domain 3.2E-24
Pfam IPR000008 EMBL-EBI C2 domain 5.8E-30
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_491853.2 1 15-37
T23H2.2 1 15-37
SNAP00000032983 1 36-58
GENEFINDER00000032992 1 15-37
Sequence
Target Sequence 
>C. ELEGANS:174108_S_AT
aatggttctatctcggagttggtggagccgtcggtctcgcggctcttgtagccgttgccg
ctcttctcgcagttcgtaaacgtcgtcaatatccgtcacttcttcttcccccgagacagg
tgattgctgtccgtggtggatttcccaagggccctggaggcctaaagcagagcccatctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATGGTTCTATCTCGGAGTTGGTGG 295 159 78 Antisense
GTTCTATCTCGGAGTTGGTGGAGCC 102 443 82 Antisense
CTCTTCTCGCAGTTCGTAAACGTCG 214 229 138 Antisense
TCTCGCAGTTCGTAAACGTCGTCAA 32 597 142 Antisense
AACGTCGTCAATATCCGTCACTTCT 88 143 156 Antisense
CTTCCCCCGAGACAGGTGATTGCTG 426 217 182 Antisense
AGGTGATTGCTGTCCGTGGTGGATT 586 57 195 Antisense
TGTCCGTGGTGGATTTCCCAAGGGC 125 557 205 Antisense
TCCCAAGGGCCCTGGAGGCCTAAAG 709 525 220 Antisense
GGCCCTGGAGGCCTAAAGCAGAGCC 33 543 227 Antisense
GGAGGCCTAAAGCAGAGCCCATCTC 552 515 233 Antisense
Sequence Source Affymetrix Proprietary Database