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[174052_at] Protein phosphatase 2C (2 domains)

Description C68133 /REP_DB=TREMBL Accession /GB=C68133 /CHR=3 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk279g8 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 86      6grp_high1_10_10 > 77      4grp_highest_8_8 > 15      4grp_high_8_8 > 06      6grp_highest_nonorm > 92      6grp_total > 68      4grp_total > 02      6grp_highest_sub > Da      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1417
1 2 3 4 range
A 264.4
(-2.7)
P 		225.4
(-3)
P 		273
(-2.6)
P 		956.9
(3)
P 		732
B 187.2
(-3)
P 		294.4
(-2.5)
P 		217
(-2.9)
P 		1604.1
(3)
P 		1417
C 205
(-3)
P 		278.9
(-2.6)
P 		280.4
(-2.5)
P 		1201.2
(3)
P 		996
avr 218.9
(-3) 		266.2
(-2.7) 		256.8
(-2.8) 		1254.1
(3) 		1035

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 541
1 2 3 4 5 6 range
A 185.1
(-2.6)
P 		207.7
(-2.3)
P 		161.3
(-2.8)
P 		144.9
(-3)
P 		315.9
(-1.1)
P 		685.9
(3)
P 		541
B 283.4
(-1.4)
P 		237.5
(-1.9)
P 		146
(-3)
P 		164.7
(-2.8)
P 		255.6
(-1.7)
P 		651
(3)
P 		505
C 169.4
(-3)
P 		266.3
(-1.6)
P 		176.3
(-2.9)
P 		190
(-2.7)
P 		173.7
(-2.9)
P 		587.9
(3)
P 		419
avr 212.6
(-2.4) 		237.2
(-2.1) 		161.2
(-3) 		166.5
(-2.9) 		248.4
(-1.9) 		641.6
(3) 		480
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 293
1 2 3 4 range
A 96.3
(0.1)
P 		48.9
(-3)
P 		71.4
(-1.5)
P 		140.1
(3)
P 		91
B 59.7
(-2.8)
P 		72.7
(-2.5)
P 		50.3
(-3)
P 		341.8
(3)
P 		292
C 67.8
(-3)
P 		80.2
(-2.4)
P 		97.7
(-1.7)
P 		202.5
(3)
P 		135
avr 74.6
(-2.7) 		67.3
(-3) 		73.1
(-2.8) 		228.1
(3) 		161

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 209
1 2 3 4 5 6 range
A 34.1
(-3)
P 		73.9
(-1.2)
P 		35.1
(-3)
P 		36.7
(-2.9)
P 		95.3
(-0.2)
P 		167
(3)
P 		133
B 98.6
(-1.2)
P 		79
(-1.7)
P 		35.4
(-3)
P 		43.6
(-2.8)
P 		103.8
(-1)
P 		242.8
(3)
P 		207
C 62.8
(-2.1)
P 		81.3
(-1.4)
P 		44.9
(-2.7)
P 		38.2
(-3)
P 		56.2
(-2.3)
P 		196.8
(3)
P 		159
avr 65.2
(-2) 		78.1
(-1.5) 		38.5
(-3) 		39.5
(-3) 		85.1
(-1.3) 		202.2
(3) 		164
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174052_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20938
Sequence Type Exemplar sequence
Representative Public ID C68133 NCBI
Target Description C68133 /REP_DB=TREMBL Accession /GB=C68133 /CHR=3 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk279g8 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066961(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066961 NCBI Caenorhabditis elegans W09D10.4 (W09D10.4) mRNA, complete cds. 11/11 None
W09D10.4 ENSEMBL cdna:known chromosome:CEL140:III:10711442:10716068:-1 gene:W09D10.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10711862-10712142(-) 100.0 100.0
Public Domain and Genome References
Gene Title Protein phosphatase 2C (2 domains)
Ensembl W09D10.4
Entrez Gene 176497 Entrez gene
SwissProt O18183 EMBL-EBI
WormBase CE16565 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:267247_AT expressed protein at
CANINE:1587763_AT similar to T-cell activation protein phosphatase 2C cfa
CANINE_2:CFA.14778.1.A1_AT similar to T-cell activation protein phosphatase 2C cfa
CANINE_2:CFAAFFX.13463.1.S1_AT similar to T-cell activation protein phosphatase 2C cfa
DROSOPHILA_2:1629433_AT dm
DROSGENOME1:147984_AT dm
CHICKEN:GGA.12843.1.S1_AT T-cell activation protein phosphatase 2C gga
HU35KSUBA:AA504439_AT T-cell activation protein phosphatase 2C hs
HU35KSUBC:RC_AA521311_AT T-cell activation protein phosphatase 2C hs
HU35KSUBD:RC_T71333_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.153089.0.A1_3P_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.13854.0.A2_3P_AT T-cell activation protein phosphatase 2C hs
U133_X3P:HS.13854.0.A1_3P_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:225204_AT T-cell activation protein phosphatase 2C hs
HG-U133B:225204_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:225213_AT T-cell activation protein phosphatase 2C hs
HG-U133B:225213_AT T-cell activation protein phosphatase 2C hs
HG-U133_PLUS_2:235744_AT T-cell activation protein phosphatase 2C hs
HG-U133B:235744_AT T-cell activation protein phosphatase 2C hs
HG-U95C:48929_AT T-cell activation protein phosphatase 2C hs
HG-U95C:66208_AT T-cell activation protein phosphatase 2C hs
HG-U95E:83379_AT T-cell activation protein phosphatase 2C hs
HG-U95E:68599_AT T-cell activation protein phosphatase 2C hs
MU11KSUBA:AA185309_S_AT RIKEN cDNA 9130017A15 gene mm
MG-U74AV2:99503_AT RIKEN cDNA 9130017A15 gene mm
MOE430A:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MOUSE430A_2:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MOUSE430_2:1455958_S_AT RIKEN cDNA 9130017A15 gene mm
MU19KSUBA:TC17666_AT RIKEN cDNA 9130017A15 gene, mRNA (cDNA clone MGC:93006 IMAGE:30537082) mm
MU19KSUBC:TC37288_AT RIKEN cDNA 9130017A15 gene, mRNA (cDNA clone MGC:93006 IMAGE:30537082) mm
RAE230A:1375498_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1375498_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230B:1378246_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1378246_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230B:1379953_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1379953_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAE230A:1388522_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RAT230_2:1388522_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
RG-U34C:RC_AI170820_AT Similar to T-cell activation protein phosphatase 2C (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07860 Hypothetical protein W09D10.4 [Caenorhabditis elegans] ref|NP_499362.1| W09D10.4 [Caenorhabditis elegans] 1.0E-158
blast CAE71413 Hypothetical protein CBG18323 [Caenorhabditis briggsae] 1.0E-152
blast XP_624085 PREDICTED: similar to GA11388-PA [Apis mellifera] 6.0E-64
Protein Domains
Database ID Description E-Value
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 9.1E-4
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 0.0058
Sequence
Target Sequence 
>C. ELEGANS:174052_AT
caaatatcaattttcgctccctttttctcccctaaagtagggaaaattatcgttttttga
gatctcctcctccctattttgctccttttctccccgaaattccccctaacttgtgccttt
tttgagatttttttattggataacgccacgttttccacgtaatcgggagttttttacacg
taataagggtaatcaataatgtttttttttctagtgacttagcgtcatttgtgtcttata
ttgctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAATATCAATTTTCGCTCCCTTTT 682 193 17 Antisense
TATCGTTTTTTGAGATCTCCTCCTC 33 659 64 Antisense
CCCTAACTTGTGCCTTTTTTGAGAT 498 257 120 Antisense
TAACTTGTGCCTTTTTTGAGATTTT 595 637 123 Antisense
GAGATTTTTTTATTGGATAACGCCA 246 397 140 Antisense
TTATTGGATAACGCCACGTTTTCCA 403 611 149 Antisense
GCCACGTTTTCCACGTAATCGGGAG 183 279 161 Antisense
TGTTTTTTTTTCTAGTGACTTAGCG 554 559 216 Antisense
AGTGACTTAGCGTCATTTGTGTCTT 48 61 229 Antisense
ACTTAGCGTCATTTGTGTCTTATAT 435 103 233 Antisense
GCGTCATTTGTGTCTTATATTGCTG 681 291 238 Antisense
Sequence Source Affymetrix Proprietary Database