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[174026_at] Src homology domain 3, tyrosine-protein kinase (ACK subfamily)

Description g6706146 /REP_DB=GenBank Identifier /CHR=4 /FEA=Genomic Cluster
Cluster 6grp_highest_10_10 > 52      6grp_high1_10_10 > 26      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 31      6grp_total > 26      4grp_total > 31      6grp_highest_sub > 01_02      6grp_cgc > 14      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 818
1 2 3 4 range
A 1073
(3)
P 		729.3
(-3)
P 		875.1
(-0.5)
P 		929.8
(0.5)
P 		344
B 1458.5
(3)
P 		960.4
(-0.7)
P 		640.3
(-3)
P 		1187.1
(1)
P 		818
C 1430.5
(3)
P 		693.1
(-3)
P 		866
(-1.6)
P 		1042.5
(-0.2)
P 		737
avr 1320.7
(3) 		794.3
(-3) 		793.8
(-3) 		1053.1
(-0) 		527

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 664
1 2 3 4 5 6 range
A 1196.5
(2.3)
P 		1270.9
(3)
P 		873.5
(-0.9)
P 		654.2
(-3)
P 		984.5
(0.2)
P 		985.9
(0.2)
P 		617
B 1100.2
(1.1)
P 		1256
(3)
P 		776.4
(-2.7)
P 		988.9
(-0.2)
P 		754.1
(-3)
P 		914.3
(-1.1)
P 		502
C 1317.9
(3)
P 		1184.3
(1.6)
P 		1059.5
(0.3)
P 		837.1
(-2.1)
P 		753.4
(-3)
P 		899.8
(-1.4)
P 		565
avr 1204.9
(2.5) 		1237.1
(3) 		903.1
(-1.9) 		826.7
(-3) 		830.7
(-2.9) 		933.3
(-1.4) 		410
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 337
1 2 3 4 range
A 390.7
(3)
P 		158.3
(-2.5)
P 		228.8
(-0.8)
P 		136.1
(-3)
P 		255
B 465.1
(3)
P 		237.2
(-1.3)
P 		148.4
(-3)
P 		253
(-1)
P 		317
C 473.5
(3)
P 		199.3
(-2.5)
P 		301.8
(-0.5)
P 		175.8
(-3)
P 		298
avr 443.1
(3) 		198.3
(-2.8) 		226.3
(-2.1) 		188.3
(-3) 		255

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 323
1 2 3 4 5 6 range
A 220.6
(-1.9)
P 		452
(3)
P 		190.2
(-2.5)
P 		165.9
(-3)
P 		297.1
(-0.2)
P 		240
(-1.4)
P 		286
B 382.8
(2.1)
P 		418.1
(3)
P 		188.5
(-3)
P 		261.9
(-1.1)
P 		306.4
(0.1)
P 		340.9
(1)
P 		230
C 488.5
(3)
P 		361.4
(0.6)
P 		269.7
(-1.1)
P 		168.3
(-3)
P 		243.8
(-1.6)
P 		301.2
(-0.5)
P 		320
avr 364
(1.7) 		410.5
(3) 		216.1
(-2.5) 		198.7
(-3) 		282.4
(-0.6) 		294
(-0.3) 		212
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 174026_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21461
Sequence Type Exemplar sequence
Representative Public ID 6706146 NCBI
Target Description g6706146 /REP_DB=GenBank Identifier /CHR=4 /FEA=Genomic Cluster
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070017(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070017 NCBI Caenorhabditis elegans A Ras-regulating Kinase family member (ark-1) (ark-1) mRNA, complete cds. 11/11 A 
C01C7.1 ENSEMBL cdna:known chromosome:CEL140:IV:12622064:12630993:-1 gene:C01C7.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12622120-12622427(-) 100.0 100.0
Public Domain and Genome References
Gene Title Src homology domain 3, tyrosine-protein kinase (ACK subfamily)
Gene Symbol ark-1
Ensembl C01C7.1
Entrez Gene 178218 Entrez gene
SwissProt O45232 EMBL-EBI
WormBase CE26967 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05120 Hypothetical protein C01C7.1 [Caenorhabditis elegans] emb|CAB65957.1| Ack related non-receptor tyrosine kinase [Caenorhabditis elegans] ref|NP_502418.1| A Ras-regulating Kinase family member (ark-1) [Caenorhabditis elegans] 0.0
blast CAE67920 Hypothetical protein CBG13518 [Caenorhabditis briggsae] 0.0
blast XP_624955 PREDICTED: similar to ENSANGP00000009263 [Apis mellifera] 1.0E-117
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.3E-72
Pfam IPR000095 EMBL-EBI PAK-box/P21-Rho-binding 2.1E-13
Sequence
Target Sequence 
>C. ELEGANS:174026_AT
atattgttattttctcccatgttttcctacatgttttccatcccgctcaattatttatat
accggtgattctttcccatttccctaaaatattgttttcgcccagatgtttgatttttcc
ccaattttacgactgtttcttgttgaatattcgtgtactcttttatataaccaaaactaa
gaaaatttctatgtattccagtattatcatatatttactttattcgcata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATATTGTTATTTTCTCCCATGTTTT 168 19 56 Antisense
ATGTTTTCCTACATGTTTTCCATCC 691 45 74 Antisense
TTTCCATCCCGCTCAATTATTTATA 514 669 90 Antisense
ATATACCGGTGATTCTTTCCCATTT 264 15 112 Antisense
TCTTTCCCATTTCCCTAAAATATTG 687 613 125 Antisense
AATATTGTTTTCGCCCAGATGTTTG 419 173 143 Antisense
GCCCAGATGTTTGATTTTTCCCCAA 423 283 155 Antisense
TCCCCAATTTTACGACTGTTTCTTG 599 595 173 Antisense
ATTCGTGTACTCTTTTATATAACCA 346 9 204 Antisense
ATTTCTATGTATTCCAGTATTATCA 225 17 240 Antisense
ATCATATATTTACTTTATTCGCATA 152 31 261 Antisense
Sequence Source GenBank