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[174007_s_at] Monooxygenase

Description CE1672 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=R07B7.5 /5_PRIME_EXT_DB=WormBase Gene ID /GB=T02167 /WB_GENE_ID=R07B7.5 /WP=CE06267 /CHR=5 /FEA=Genomic Cluster /DEF=Monooxygenase; wEST02888 Early embryo, Stratagene (cat. no. 937007) Caenorhabditis elegans cDNA clone CESAA20, mRNA sequence.
Cluster 6grp_high1_10_10 > 52      4grp_highest_8_8 > 43      4grp_high_8_8 > 40      6grp_total > 52      4grp_total > 55      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 668
1 2 3 4 range
A 1081.5
(3)
P 		467
(-3)
P 		644.7
(-1.3)
P 		490.1
(-2.8)
P 		615
B 1135.2
(3)
P 		546.3
(-2.8)
P 		651.4
(-1.8)
P 		524.5
(-3)
P 		611
C 1070
(3)
P 		538.6
(-3)
P 		682.2
(-1.4)
P 		601.5
(-2.3)
P 		531
avr 1095.6
(3) 		517.3
(-3) 		659.4
(-1.5) 		538.7
(-2.8) 		578

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1074
1 2 3 4 5 6 range
A 485.5
(-1.2)
P 		684.5
(0)
P 		1180.9
(3)
P 		773.2
(0.6)
P 		402.7
(-1.7)
P 		179.2
(-3)
A 		1002
B 395.7
(-2.1)
P 		670
(-0.4)
P 		1252.7
(3)
P 		703.1
(-0.2)
P 		428.3
(-1.9)
P 		236.5
(-3)
P 		1016
C 286.6
(-2.7)
P 		768.6
(0.8)
P 		1059
(3)
P 		852.5
(1.5)
P 		380.2
(-2)
P 		248.9
(-3)
P 		810
avr 389.3
(-1.9) 		707.7
(0.1) 		1164.2
(3) 		776.3
(0.5) 		403.7
(-1.8) 		221.5
(-3) 		943
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 322
1 2 3 4 range
A 393.8
(3)
P 		101.4
(-2.4)
P 		168.5
(-1.2)
P 		71.7
(-3)
P 		322
B 362
(3)
P 		134.9
(-2.4)
P 		150.9
(-2.1)
P 		111.8
(-3)
P 		250
C 354.2
(3)
P 		154.8
(-1.7)
P 		237.8
(0.2)
P 		101.4
(-3)
P 		253
avr 370
(3) 		130.4
(-2.2) 		185.7
(-1) 		95
(-3) 		275

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 261
1 2 3 4 5 6 range
A 89.5
(-1.7)
P 		243.4
(2.6)
P 		257.2
(3)
P 		196.1
(1.3)
P 		121.5
(-0.8)
P 		43.6
(-3)
A 		214
B 137.7
(-1.6)
P 		223
(0.7)
P 		304.2
(3)
P 		186.2
(-0.3)
P 		174
(-0.6)
P 		88.2
(-3)
P 		216
C 106.2
(-2.3)
P 		234.5
(1.9)
P 		269.5
(3)
P 		171.4
(-0.2)
P 		123
(-1.7)
P 		83.3
(-3)
P 		186
avr 111.1
(-1.8) 		233.6
(1.7) 		277
(3) 		184.6
(0.3) 		139.5
(-1) 		71.7
(-3) 		205
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 174007_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25560
Sequence Type Exemplar sequence
Representative Public ID CE1672 NCBI
Target Description CE1672 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=R07B7.5 /5_PRIME_EXT_DB=WormBase Gene ID /GB=T02167 /WB_GENE_ID=R07B7.5 /WP=CE06267 /CHR=5 /FEA=Genomic Cluster /DEF=Monooxygenase; wEST02888 Early embryo, Stratagene (cat. no. 937007) Caenorhabditis elegans cDNA clone CESAA20, mRNA sequence.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073624(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073624 NCBI Caenorhabditis elegans R07B7.5 (Monooxygenase) mRNA, complete cds. 11/11 None
SNAP00000027086 ENSEMBL cdna:SNAP chromosome:CEL140:V:12071380:12073107:-1 11/11 None
GENEFINDER00000027108 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12071380:12073107:-1 11/11 None
R07B7.5 ENSEMBL cdna:known chromosome:CEL140:V:12071368:12073107:-1 gene:R07B7.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12071378-12073108(-) 100.0 100.0
Public Domain and Genome References
Gene Title Monooxygenase
Ensembl R07B7.5
Entrez Gene 179657 Entrez gene
SwissProt Q21795 EMBL-EBI
WormBase CE06267 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1586955_AT similar to kynurenine 3-monooxygenase cfa
CANINE_2:CFA.14036.1.A1_AT similar to kynurenine 3-monooxygenase cfa
CANINE_2:CFA.14036.1.A1_S_AT similar to kynurenine 3-monooxygenase cfa
CANINE_2:CFAAFFX.24086.1.S1_AT similar to kynurenine 3-monooxygenase cfa
DROSOPHILA_2:1631012_AT cinnabar dm
DROSGENOME1:143103_AT cinnabar dm
CHICKEN:GGAAFFX.4675.1.S1_AT similar to kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) gga
HG-U133_PLUS_2:205307_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A:205307_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A_2:205307_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133_PLUS_2:211138_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A:211138_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-FOCUS:211138_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A_2:211138_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133_PLUS_2:205306_X_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A_2:205306_X_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U133A:205306_X_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HU35KSUBB:RC_R65593_S_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HU35KSUBB:RC_N29353_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HUGENEFL:Y13153_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
U133_X3P:G4504890_3P_A_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
U133_X3P:HS.107318.0.A1_3P_A_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
HG-U95AV2:39559_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) hs
MOE430A:1418998_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) mm
MOUSE430A_2:1418998_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) mm
MOUSE430_2:1418998_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) mm
MG-U74BV2:111457_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) mm
MU19KSUBA:TC17720_AT Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo), mRNA mm
RG-U34A:AF056031_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) rn
RAE230A:1368915_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) rn
RAT230_2:1368915_AT kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) rn
YEAST_2:1775992_AT Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
6725 aromatic compound metabolism inferred from electronic annotation QuickGO AmiGO
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00114 Hypothetical protein R07B7.5 [Caenorhabditis elegans] ref|NP_506025.1| R07B7.5 [Caenorhabditis elegans] 0.0
blast CAE75381 Hypothetical protein CBG23368 [Caenorhabditis briggsae] 0.0
blast XP_796984 PREDICTED: similar to kynurenine 3-monooxygenase [Strongylocentrotus purpuratus] 1.0E-108
Protein Domains
Database ID Description E-Value
Pfam IPR000733 EMBL-EBI Flavoprotein monooxygenase 2.6E-54
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506025.1 2 4-21,432-454
R07B7.5 2 4-21,432-454
SNAP00000027086 2 4-21,432-454
GENEFINDER00000027108 2 4-21,432-454
Sequence
Target Sequence 
>C. ELEGANS:174007_S_AT
aacttcccagatgcatttttattacttggaagggaacacatagcagatacatttaatcga
gtaaaaccacaacctcttgtttcaatcaaatgttcacctcattcattcttcgataatctc
gttctaatgggagatgctgctcatgcaatggttcctttttacggacagggaatgaattgg
ggctttgaggattgtcttgtgtttagtgaaacactcgaggagtacggaaatgatattgcc
aaagcagtcaaagtctactcagacggtcgagtcaacgatgctcattccattaatgatctt
gcaatgtacaactacgaagaactcaaggatcttgtgaataaaagctcctacaaacttcgt
aaaaagtttgatacaatcatgaactcaatatttccaaaaagctggattccattgtactct
atggttactttctcacgaattccatactcggaagtaattgaaagaagaaaaaggcaagat
aagattctgtcaagaataatgacaactacatctacattagctttgattggggctgctgct
ggtattt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACTTCCCAGATGCATTTTTATTAC 698 137 824 Antisense
AAACCACAACCTCTTGTTTCAATCA 543 123 887 Antisense
AAATGTTCACCTCATTCATTCTTCG 37 121 911 Antisense
GAGATGCTGCTCATGCAATGGTTCC 341 395 954 Antisense
GCAATGGTTCCTTTTTACGGACAGG 325 315 968 Antisense
AAGTCTACTCAGACGGTCGAGTCAA 274 155 1074 Antisense
GTCGAGTCAACGATGCTCATTCCAT 396 473 1089 Antisense
GTACTCTATGGTTACTTTCTCACGA 369 459 1237 Antisense
CTTTCTCACGAATTCCATACTCGGA 476 221 1251 Antisense
GACAACTACATCTACATTAGCTTTG 641 365 1324 Antisense
TTGATTGGGGCTGCTGCTGGTATTT 565 705 1346 Antisense
Sequence Source Affymetrix Proprietary Database