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[173981_at] serine/threonine kinase (CDC2/CDKX subfamily)

Description AV191881 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZC504.3 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV191881 /WB_GENE_ID=ZC504.3 /WP=CE03811 /CHR=X /FEA=Genomic Cluster /DEF=serine-threonine kinase (CDC2-CDKX subfamily); Caenorhabditis elegans cDNA clone:yk599a2 : 5prime end, single read.
Cluster 6grp_high1_10_10 > 35      4grp_high_8_8 > 08      6grp_total > 27      4grp_total > 39      6grp_high1_sub > 02      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 73
1 2 3 4 range
A 115.6
(3)
P 		54
(-3)
P 		54
(-3)
P 		76.4
(-0.8)
P 		62
B 60.8
(-0.2)
P 		42.6
(-3)
A 		72.7
(1.6)
P 		82.2
(3)
P 		40
C 82.1
(3)
P 		74.1
(1.4)
P 		75.8
(1.7)
P 		52.6
(-3)
A 		30
avr 86.2
(3) 		56.9
(-3) 		67.5
(-0.8) 		70.4
(-0.2) 		29

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 92
1 2 3 4 5 6 range
A 72.2
(-1.1)
P 		54.5
(-2.8)
A 		88.8
(0.5)
P 		52.9
(-3)
P 		114.9
(3)
P 		61.4
(-2.2)
P 		62
B 130.1
(3)
P 		89.8
(-0.3)
P 		57.4
(-3)
P 		69.2
(-2)
P 		71.1
(-1.9)
P 		103.1
(0.8)
P 		73
C 61.3
(-1.1)
P 		111.7
(3)
P 		72.6
(-0.2)
P 		84.1
(0.8)
P 		37.8
(-3)
P 		77.6
(0.2)
P 		74
avr 87.9
(3) 		85.3
(2.2) 		72.9
(-1.7) 		68.7
(-3) 		74.6
(-1.2) 		80.7
(0.7) 		19
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 42.1
(3)
P 		11.7
(-2.9)
P 		14.1
(-2.4)
P 		11.2
(-3)
P 		31
B 19.4
(3)
P 		10.5
(-3)
A 		16.8
(1.2)
P 		17.5
(1.7)
P 		9
C 27.2
(3)
P 		21.3
(1.1)
P 		26.4
(2.7)
P 		8.9
(-3)
A 		18
avr 29.6
(3) 		14.5
(-2.3) 		19.1
(-0.7) 		12.5
(-3) 		17

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 33
1 2 3 4 5 6 range
A 13.3
(-3)
P 		19.4
(-1.3)
A 		19.3
(-1.3)
P 		13.4
(-3)
P 		34.7
(3)
P 		14.9
(-2.6)
P 		21
B 45.3
(3)
P 		29.9
(0.1)
P 		13.9
(-3)
P 		18.3
(-2.2)
P 		28.9
(-0.1)
P 		38.5
(1.7)
P 		31
C 22.7
(-0.1)
P 		34.1
(3)
P 		18.5
(-1.3)
P 		16.9
(-1.7)
P 		12.2
(-3)
P 		26
(0.8)
P 		22
avr 27.1
(2.6) 		27.8
(3) 		17.2
(-2.5) 		16.2
(-3) 		25.3
(1.7) 		26.5
(2.3) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173981_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25947
Sequence Type Exemplar sequence
Representative Public ID AV191881 NCBI
Target Description AV191881 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZC504.3 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV191881 /WB_GENE_ID=ZC504.3 /WP=CE03811 /CHR=X /FEA=Genomic Cluster /DEF=serine-threonine kinase (CDC2-CDKX subfamily); Caenorhabditis elegans cDNA clone:yk599a2 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077345(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077345 NCBI Caenorhabditis elegans ZC504.3 (ZC504.3) mRNA, complete cds. 11/11 None
ZC504.3 ENSEMBL cdna:known chromosome:CEL140:X:10416629:10420005:-1 gene:ZC504.3 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_065571 1/11 Cross Hyb Matching Probes None
F17C8.4.3 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10416639-10420006(-) 97.4 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase (CDC2/CDKX subfamily)
Ensembl ZC504.3
Entrez Gene 181247 Entrez gene
SwissProt Q23357 EMBL-EBI
WormBase CE03811 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247384_AT protein kinase family protein at
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90342 Hypothetical protein ZC504.3 [Caenorhabditis elegans] ref|NP_509746.1| ZC504.3 [Caenorhabditis elegans] 0.0
blast CAE70578 Hypothetical protein CBG17235 [Caenorhabditis briggsae] 0.0
blast AAA62523 Hypothetical protein B0495.2 [Caenorhabditis elegans] ref|NP_495617.1| B0495.2 [Caenorhabditis elegans] sp|Q09437|YP62_CAEEL Putative serine/threonine-protein kinase B0495.2 1.0E-178
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-72
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 9.0E-75
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.6E-84
Sequence
Target Sequence 
>C. ELEGANS:173981_AT
gaatacaaagtcttttgacaattgaattttatactgaggctattgaaagctctccaaaat
tttttatggcgattccaagttttaagaaaaagtgctccagttaaaatctccatttttgtt
ttatattcataattttttgtacatcactctctcacttctccaccatccattgtttttgtc
attgtttttgccaattttgtcattgatcttttcttaactagtc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATACAAAGTCTTTTGACAATTGA 111 327 2337 Antisense
GACAATTGAATTTTATACTGAGGCT 646 363 2353 Antisense
TACTGAGGCTATTGAAAGCTCTCCA 448 641 2368 Antisense
TTGAAAGCTCTCCAAAATTTTTTAT 501 701 2379 Antisense
CAAAATTTTTTATGGCGATTCCAAG 102 189 2391 Antisense
AAGTGCTCCAGTTAAAATCTCCATT 396 159 2426 Antisense
AATTTTTTGTACATCACTCTCTCAC 457 175 2467 Antisense
CTCCACCATCCATTGTTTTTGTCAT 466 235 2494 Antisense
CATTGTTTTTGTCATTGTTTTTGCC 628 217 2504 Antisense
TTGCCAATTTTGTCATTGATCTTTT 300 701 2524 Antisense
GTCATTGATCTTTTCTTAACTAGTC 654 467 2535 Antisense
Sequence Source Affymetrix Proprietary Database