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[173944_at] serine proteinase inhibitor (kunitz type)

Description CEK046H5R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=K10D3.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D34506 /WB_GENE_ID=K10D3.4 /WP=CE06173 /CHR=1 /FEA=Genomic Cluster /DEF=serine proteinase inhibitor (kunitz type); C.elegans cDNA clone yk46h5 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 04      4grp_highest_8_8 > 02      4grp_high_8_8 > 45      6grp_highest_nonorm > 13      6grp_total > 14      4grp_total > 50      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5590
1 2 3 4 range
A 359.1
(-2.8)
P 		5727.6
(3)
P 		4424.2
(1.6)
P 		208.3
(-3)
P 		5519
B 372.3
(-2.7)
P 		5590.7
(3)
P 		4493.5
(1.8)
P 		137.8
(-3)
P 		5453
C 346.5
(-2.8)
P 		5597.9
(3)
P 		4220.3
(1.5)
P 		190.3
(-3)
P 		5408
avr 359.3
(-2.8) 		5638.7
(3) 		4379.3
(1.6) 		178.8
(-3) 		5460

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3532
1 2 3 4 5 6 range
A 4318.2
(3)
P 		3286.1
(1.2)
P 		2615.3
(0.1)
P 		1810.6
(-1.3)
P 		1931.7
(-1.1)
P 		786.4
(-3)
P 		3532
B 3790.4
(3)
P 		3319.8
(2)
P 		2806
(0.9)
P 		2630.7
(0.5)
P 		1368.2
(-2.2)
P 		972.6
(-3)
P 		2818
C 3523.7
(3)
P 		3207.8
(2.3)
P 		2334.9
(0.3)
P 		2165
(-0.1)
P 		1801.6
(-0.9)
P 		888.8
(-3)
P 		2635
avr 3877.4
(3) 		3271.2
(1.8) 		2585.4
(0.4) 		2202.1
(-0.4) 		1700.5
(-1.4) 		882.6
(-3) 		2995
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1580
1 2 3 4 range
A 130.7
(-2.5)
P 		1243.3
(3)
P 		1156.6
(2.6)
P 		30.5
(-3)
P 		1213
B 118.7
(-2.6)
P 		1380.8
(3)
P 		1041.2
(1.5)
P 		29.4
(-3)
P 		1351
C 114.7
(-2.7)
P 		1609.4
(3)
P 		1470.9
(2.5)
P 		32.1
(-3)
P 		1577
avr 121.4
(-2.6) 		1411.2
(3) 		1222.9
(2.2) 		30.7
(-3) 		1381

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1127
1 2 3 4 5 6 range
A 796
(0.7)
P 		1168.7
(3)
P 		569.6
(-0.7)
P 		459.2
(-1.4)
P 		582.9
(-0.6)
P 		191.5
(-3)
P 		977
B 1318.9
(3)
P 		1105
(1.7)
P 		681.4
(-1)
P 		696.8
(-0.9)
P 		555.9
(-1.8)
P 		362.7
(-3)
P 		956
C 1306.1
(3)
P 		978.8
(1.1)
P 		594.3
(-1.2)
P 		435.4
(-2.2)
P 		583
(-1.3)
P 		297.5
(-3)
P 		1009
avr 1140.3
(3) 		1084.2
(2.6) 		615.1
(-0.7) 		530.5
(-1.3) 		573.9
(-1) 		283.9
(-3) 		856
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173944_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22637
Sequence Type Exemplar sequence
Representative Public ID CEK046H5R NCBI
Target Description CEK046H5R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=K10D3.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D34506 /WB_GENE_ID=K10D3.4 /WP=CE06173 /CHR=1 /FEA=Genomic Cluster /DEF=serine proteinase inhibitor (kunitz type); C.elegans cDNA clone yk46h5 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059619(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059619 NCBI Caenorhabditis elegans K10D3.4 (K10D3.4) mRNA, complete cds. 11/11 None
K10D3.4 ENSEMBL cdna:known chromosome:CEL140:I:7142870:7148105:-1 gene:K10D3.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7142829-7147735(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine proteinase inhibitor (kunitz type)
Ensembl K10D3.4
Entrez Gene 172452 Entrez gene
SwissProt Q21418 EMBL-EBI
WormBase CE06173 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA99886 Hypothetical protein K10D3.4 [Caenorhabditis elegans] ref|NP_492020.1| K10D3.4 [Caenorhabditis elegans] 0.0
blast CAE74254 Hypothetical protein CBG21943 [Caenorhabditis briggsae] 0.0
blast CAE62775 Hypothetical protein CBG06944 [Caenorhabditis briggsae] 1.0E-170
Protein Domains
Database ID Description E-Value
Pfam IPR006149 EMBL-EBI Nematode-specific EB region 8.6E-32
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 5.7E-23
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.5E-16
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 5.8E-30
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.4E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-30
Sequence
Target Sequence 
>C. ELEGANS:173944_AT
taaacaagagctccggggttcacgactttgttctctaaaatttctaaattctttcattta
ttttttgatgttttttcttgactttttcgccatctcattcccacgtacatgtgtattccc
caccaaacaaataatttttctgcataacttacactgtacggttgtctgtttttcctctat
caattgttcattttcctctcattgtttttccatgtaactggaaaaaatcgatgccaaaaa
gagcctgaaaatcagaaatctatattttcaaagttctgttttgacgtcaatcgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAAACAAGAGCTCCGGGGTTCACGA 43 627 2780 Antisense
GGTTCACGACTTTGTTCTCTAAAAT 476 505 2796 Antisense
CATCTCATTCCCACGTACATGTGTA 247 213 2870 Antisense
CATGTGTATTCCCCACCAAACAAAT 347 209 2887 Antisense
TTTCTGCATAACTTACACTGTACGG 229 671 2916 Antisense
CACTGTACGGTTGTCTGTTTTTCCT 485 181 2931 Antisense
TCTGTTTTTCCTCTATCAATTGTTC 174 607 2944 Antisense
ATCAATTGTTCATTTTCCTCTCATT 166 27 2958 Antisense
TTTCCTCTCATTGTTTTTCCATGTA 9 671 2971 Antisense
AAATCGATGCCAAAAAGAGCCTGAA 499 117 3004 Antisense
AAAGTTCTGTTTTGACGTCAATCGT 218 123 3049 Antisense
Sequence Source Affymetrix Proprietary Database