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[173943_s_at] CDC25/string

Description AV194571 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK637.11 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV194571 /WB_GENE_ID=ZK637.11 /WP=CE00429 /CHR=3 /FEA=Genomic Cluster /GEN=cdc-25.3 /DEF=CDC25-string; Caenorhabditis elegans cDNA clone:yk631b11 : 5prime end, single read.
Cluster 6grp_total > 78      4grp_total > 18      6grp_cgc > 49      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 3.2
(-3)
A 		5.6
(-0.8)
A 		4
(-2.3)
A 		9.7
(3)
A 		7
B 5
(-1.3)
A 		5.5
(3)
A 		4.8
(-3)
A 		5.5
(3)
A 		1
C 3.8
(-3)
A 		12.3
(-0.5)
A 		5.4
(-2.5)
A 		24
(3)
A 		20
avr 4
(-3) 		7.8
(-0.5) 		4.7
(-2.5) 		13.1
(3) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 580
1 2 3 4 5 6 range
A 7.4
(-2.9)
A 		3.9
(-3)
A 		2.5
(-3)
A 		2.8
(-3)
A 		127.1
(-0.9)
A 		358.7
(3)
P 		356
B 5.1
(-3)
A 		12.4
(-2.8)
A 		5.9
(-2.9)
A 		1.9
(-3)
A 		171.5
(-0.5)
A 		414.9
(3)
P 		413
C 3.9
(-3)
A 		27.4
(-2.7)
A 		2.6
(-3)
A 		2.5
(-3)
A 		184.8
(-1.1)
A 		581.8
(3)
P 		579
avr 5.5
(-3) 		14.6
(-2.8) 		3.7
(-3) 		2.4
(-3) 		161.1
(-0.9) 		451.8
(3) 		449
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3
1 2 3 4 range
A 1.2
(-1)
A 		1.2
(-1)
A 		1.1
(-3)
A 		1.4
(3)
A 		0
B 1.6
(3)
A 		1.4
(0.6)
A 		1.1
(-3)
A 		1.2
(-1.8)
A 		1
C 1.3
(-3)
A 		3.5
(1.9)
A 		1.9
(-1.7)
A 		4
(3)
A 		3
avr 1.4
(-3) 		2
(1.5) 		1.4
(-3) 		2.2
(3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 194
1 2 3 4 5 6 range
A 1.4
(-2.9)
A 		1.4
(-2.9)
A 		0.5
(-3)
A 		0.7
(-3)
A 		38.4
(-0.4)
A 		87.3
(3)
P 		87
B 1.8
(-2.9)
A 		4.1
(-2.9)
A 		1.4
(-3)
A 		0.5
(-3)
A 		69.7
(-0.3)
A 		154.7
(3)
P 		154
C 1.5
(-3)
A 		8.4
(-2.8)
A 		0.7
(-3)
A 		0.5
(-3)
A 		59.8
(-1.2)
A 		194.8
(3)
P 		194
avr 1.6
(-3) 		4.6
(-2.8) 		0.9
(-3) 		0.6
(-3) 		56
(-0.7) 		145.6
(3) 		145
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173943_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23979
Sequence Type Exemplar sequence
Representative Public ID AV194571 NCBI
Target Description AV194571 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK637.11 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV194571 /WB_GENE_ID=ZK637.11 /WP=CE00429 /CHR=3 /FEA=Genomic Cluster /GEN=cdc-25.3 /DEF=CDC25-string; Caenorhabditis elegans cDNA clone:yk631b11 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066571(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066571 NCBI Caenorhabditis elegans ZK637.11 (CDC25/string) mRNA, complete cds. 11/11 None
SNAP00000013210 ENSEMBL cdna:SNAP chromosome:CEL140:III:8916408:8917799:-1 11/11 None
GENEFINDER00000013225 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:8916408:8917799:-1 11/11 None
ZK637.11 ENSEMBL cdna:known chromosome:CEL140:III:8916321:8917833:-1 gene:ZK637.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:8916327-8917796(-) 100.0 100.0
Public Domain and Genome References
Gene Title CDC25/string
Gene Symbol cdc-25.3
Ensembl ZK637.11
Entrez Gene 176260 Entrez gene
SwissProt P30634 EMBL-EBI
WormBase CE00429 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
87 M phase of mitotic cell cycle inferred from electronic annotation QuickGO AmiGO
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
7049 cell cycle inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
8138 protein tyrosine/serine/threonine phosphatase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA77456 Hypothetical protein ZK637.11 [Caenorhabditis elegans] ref|NP_498972.1| ZK637.11 [Caenorhabditis elegans] sp|P30634|MPIP3_CAEEL M-phase inducer phosphatase cdc-25.3 (Cell division cycle related protein 25.3) 1.0E-171
blast CAE63674 Hypothetical protein CBG08176 [Caenorhabditis briggsae] 5.0E-57
blast AAB94237 Cell division cycle related protein 25.2 [Caenorhabditis elegans] ref|NP_503446.1| Cell Division Cycle related family member (cdc-25.2) [Caenorhabditis elegans] sp|O44628|MPIP2_CAEEL M-phase inducer phosphatase cdc-25.2 (Cell division cycle related protein 25.2) 2.0E-46
Protein Domains
Database ID Description E-Value
Pfam IPR001763 EMBL-EBI Rhodanese-like 4.6E-33
Sequence
Target Sequence 
>C. ELEGANS:173943_S_AT
gggagctcaaagcctgttcaatccagaaactgctgcagacttcttcttcaacaaagatgg
ttccaagaaaatcaaccggatacccattttctactgtgaatacagtcaaaaacgtggacc
aaccatggcgaacaaccttcgggaagtggacagaaaactgaattcaaatatctatccgag
atgtgattatgaggagatttatttgttggaaggaggttataaaaacttttacgctttcac
gcggggattagagaaggaacaaagagtacaactctgtgagccagataattatgtaatcat
gtttgatgatcgttataaggctgagcttcggaagcaccagttccataagaagaatgtttc
gaagccaatgaagaaatggagttcaacaacatctgtgatatctattctaacaacttctgg
aactcgtatttcgacacttcgtcagacatgtgatcccatccatgagcacgatgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGAGCTCAAAGCCTGTTCAATCCA 266 495 484 Antisense
AGAAACTGCTGCAGACTTCTTCTTC 272 73 508 Antisense
ATCAACCGGATACCCATTTTCTACT 433 27 554 Antisense
GTGGACCAACCATGGCGAACAACCT 165 491 597 Antisense
TTTTACGCTTTCACGCGGGGATTAG 99 3 710 Antisense
TGAGCTTCGGAAGCACCAGTTCCAT 541 569 805 Antisense
GGAGTTCAACAACATCTGTGATATC 618 517 861 Antisense
GTGATATCTATTCTAACAACTTCTG 655 483 878 Antisense
GGAACTCGTATTTCGACACTTCGTC 387 529 902 Antisense
GACACTTCGTCAGACATGTGATCCC 266 367 916 Antisense
GTGATCCCATCCATGAGCACGATGC 587 483 933 Antisense
Sequence Source Affymetrix Proprietary Database