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[173928_at] metabotropic glutamate receptor

Description CEK012H9R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F45H11.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D32386 /WB_GENE_ID=F45H11.4 /WP=CE17833 /CHR=1 /FEA=Genomic Cluster /GEN=mgl-2 /DEF=metabotropic glutamate receptor; C.elegans cDNA clone yk12h9 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 61      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 53      6grp_total > 61      4grp_total > 23      6grp_highest_sub > 04      6grp_cgc > 85      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 566
1 2 3 4 range
A 867.5
(3)
P 		301.7
(-3)
P 		382.4
(-2.1)
P 		614
(0.3)
P 		566
B 806.4
(3)
P 		366.3
(-2.4)
P 		315.9
(-3)
P 		703.2
(1.7)
P 		491
C 796.1
(3)
P 		348.6
(-2.9)
P 		344.7
(-3)
P 		648.7
(1)
P 		451
avr 823.3
(3) 		338.9
(-3) 		347.7
(-2.9) 		655.3
(0.9) 		484

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 883
1 2 3 4 5 6 range
A 716.5
(-0.7)
P 		641.6
(-1.7)
P 		1006.8
(2.9)
P 		1013.2
(3)
P 		895.4
(1.5)
P 		535.4
(-3)
P 		478
B 644.4
(-2.2)
P 		713.2
(-1.6)
P 		1089
(1.5)
P 		1278.5
(3)
P 		837.1
(-0.6)
P 		539.9
(-3)
P 		739
C 692.9
(-1.9)
P 		682.8
(-2)
P 		1036.7
(0.4)
P 		1415.2
(3)
P 		696.2
(-1.9)
P 		532.6
(-3)
P 		883
avr 684.6
(-1.7) 		679.2
(-1.8) 		1044.2
(1.4) 		1235.6
(3) 		809.6
(-0.7) 		536
(-3) 		700
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 250
1 2 3 4 range
A 315.9
(3)
P 		65.5
(-3)
P 		100
(-2.2)
P 		89.9
(-2.4)
P 		250
B 257.1
(3)
P 		90.5
(-2.4)
P 		73.2
(-3)
P 		149.8
(-0.5)
P 		184
C 263.5
(3)
P 		100.2
(-3)
P 		120.1
(-2.3)
P 		109.4
(-2.7)
P 		163
avr 278.8
(3) 		85.4
(-3) 		97.8
(-2.6) 		116.4
(-2) 		193

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 210
1 2 3 4 5 6 range
A 132.1
(-2.9)
P 		228.2
(1.2)
P 		219.3
(0.8)
P 		257
(2.4)
P 		270.2
(3)
P 		130.4
(-3)
P 		140
B 224.2
(-2)
P 		237.4
(-1.4)
P 		264.5
(-0.3)
P 		338.6
(2.9)
P 		340.1
(3)
P 		201.3
(-3)
P 		139
C 256.8
(1.4)
P 		208.3
(-1.3)
P 		263.8
(1.8)
P 		284.6
(3)
P 		225.3
(-0.3)
P 		178.3
(-3)
P 		106
avr 204.4
(-1.3) 		224.6
(-0.3) 		249.2
(0.9) 		293.4
(3) 		278.5
(2.3) 		170
(-3) 		123
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173928_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22623
Sequence Type Exemplar sequence
Representative Public ID CEK012H9R NCBI
Target Description CEK012H9R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F45H11.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D32386 /WB_GENE_ID=F45H11.4 /WP=CE17833 /CHR=1 /FEA=Genomic Cluster /GEN=mgl-2 /DEF=metabotropic glutamate receptor; C.elegans cDNA clone yk12h9 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060319(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060319 NCBI Caenorhabditis elegans Metabotropic GLutamate receptor family member (mgl-2) (mgl-2) mRNA, complete cds. 11/11 None
F45H11.4 ENSEMBL cdna:known chromosome:CEL140:I:10390889:10399438:-1 gene:F45H11.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10390830-10399370(-) 100.0 100.0
Public Domain and Genome References
Gene Title metabotropic glutamate receptor
Gene Symbol mgl-2
Ensembl F45H11.4
Entrez Gene 172914 Entrez gene
SwissProt Q93564 EMBL-EBI
WormBase CE33786 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.1457.1.S1_S_AT similar to glutamate receptor, metabotropic 1 cfa
CANINE_2:CFAAFFX.1460.1.S1_AT similar to glutamate receptor, metabotropic 1 cfa
CANINE_2:CFAAFFX.1460.1.S1_S_AT similar to glutamate receptor, metabotropic 1 cfa
CHICKEN:GGAAFFX.7793.4.S1_S_AT similar to metabotropic glutamate receptor gga
HG-U133_PLUS_2:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-FOCUS:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:207299_S_AT glutamate receptor, metabotropic 1 hs
HG-U133_PLUS_2:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:210939_S_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:33509_AT glutamate receptor, metabotropic 1 hs
HG-U133_PLUS_2:210940_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A:210940_S_AT glutamate receptor, metabotropic 1 hs
HG-U133A_2:210940_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:U31215_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:U31216_S_AT glutamate receptor, metabotropic 1 hs
HUGENEFL:L76627_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G945098_3P_A_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G6006005_3P_A_AT glutamate receptor, metabotropic 1 hs
U133_X3P:G1477389_3P_A_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:31468_F_AT glutamate receptor, metabotropic 1 hs
HG-U95AV2:33510_S_AT glutamate receptor, metabotropic 1 hs
MOUSE430_2:1425700_AT glutamate receptor, metabotropic 1 mm
MOE430A:1425700_AT glutamate receptor, metabotropic 1 mm
MOUSE430A_2:1425700_AT glutamate receptor, metabotropic 1 mm
RN-U34:M61099_AT glutamate receptor, metabotropic 1 rn
RG-U34A:M61099_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371180_A_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371180_A_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371181_X_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371181_X_AT glutamate receptor, metabotropic 1 rn
RAE230A:1387286_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1387286_AT glutamate receptor, metabotropic 1 rn
RAE230A:1371238_AT glutamate receptor, metabotropic 1 rn
RAT230_2:1371238_AT glutamate receptor, metabotropic 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
8067 metabotropic glutamate, GABA-B-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01699 Hypothetical protein F45H11.4 [Caenorhabditis elegans] emb|CAB01711.2| Hypothetical protein F45H11.4 [Caenorhabditis elegans] ref|NP_492720.2| Metabotropic GLutamate receptor family member (mgl-2) [Caenorhabditis elegans] 0.0
blast CAE58931 Hypothetical protein CBG02196 [Caenorhabditis briggsae] 0.0
blast CAH68968 novel protein similar to vertabrate glutamate receptor, metabotropic 1 (GRM1) [Danio rerio] 1.0E-178
Protein Domains
Database ID Description E-Value
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 1.9E-57
Pfam IPR000337 EMBL-EBI G-protein coupled receptor family 3, metabotropic glutamate receptor-like 7.0E-17
Pfam IPR004826 EMBL-EBI Maf transcription factor 3.7E-83
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.7E-66
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492720.2 6 580-602,615-637,642-661,689-711,792-809,822-844
F45H11.4 6 580-602,615-637,642-661,689-711,792-809,822-844
Sequence
Target Sequence 
>C. ELEGANS:173928_AT
gatattatcgggacacctgaaagtgaaaactgatgagcacacaaattttcactttcaaat
gtctctctcgcctgtttccgaaactcctccacatttcttatgtattattatttttacttc
aaatatttcctttctcattcttcatcacacgagttattatttccttaccgaatagtcatc
gattgcgccaacaacaatacctctgacaccaatctcgctacagtaaccccatgacgtcac
ccccgtgtagatcacgttctctttgctccgttcctcccagttttcagcactttgcacact
attacaggta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATATTATCGGGACACCTGAAAGTG 687 425 3824 Antisense
TTTTCACTTTCAAATGTCTCTCTCG 208 677 3869 Antisense
GAAACTCCTCCACATTTCTTATGTA 302 357 3903 Antisense
CAAATATTTCCTTTCTCATTCTTCA 364 193 3943 Antisense
CACACGAGTTATTATTTCCTTACCG 50 195 3969 Antisense
TACCGAATAGTCATCGATTGCGCCA 67 649 3989 Antisense
GATTGCGCCAACAACAATACCTCTG 394 433 4004 Antisense
CTCTGACACCAATCTCGCTACAGTA 473 231 4024 Antisense
CCCCGTGTAGATCACGTTCTCTTTG 607 255 4064 Antisense
TCCCAGTTTTCAGCACTTTGCACAC 607 597 4098 Antisense
AGCACTTTGCACACTATTACAGGTA 439 77 4109 Antisense
Sequence Source Affymetrix Proprietary Database