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[173906_at] Src homology domain 3

Description CEK035F1R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=Y37A1B.15 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D33754 /WB_GENE_ID=Y37A1B.15 /WP=CE24205 /CHR=4 /FEA=Genomic Cluster /GEN=gei-18 /DEF=Src homology domain 3; C.elegans cDNA clone yk35f1 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 70      6grp_high1_10_10 > 05      4grp_highest_8_8 > 42      4grp_high_8_8 > 49      6grp_highest_nonorm > 60      6grp_total > 05      4grp_total > 62      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 383
1 2 3 4 range
A 548.4
(3)
P 		300.7
(-0.9)
P 		364.3
(0.1)
P 		165.2
(-3)
P 		383
B 443.1
(3)
P 		286
(-1.3)
P 		357.4
(0.7)
P 		223
(-3)
P 		220
C 541.1
(3)
P 		370.9
(-0.4)
P 		372.1
(-0.4)
P 		238.8
(-3)
P 		302
avr 510.9
(3) 		319.2
(-0.8) 		364.6
(0.1) 		209
(-3) 		302

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 514
1 2 3 4 5 6 range
A 649
(3)
P 		437.1
(0)
P 		362.2
(-1)
P 		218.8
(-3)
P 		453.9
(0.3)
P 		247.8
(-2.6)
P 		430
B 716.4
(3)
P 		544.8
(0.4)
P 		366.7
(-2.3)
P 		349.3
(-2.6)
P 		322.2
(-3)
P 		333.8
(-2.8)
P 		394
C 528.8
(3)
P 		452.4
(1.6)
P 		282.2
(-1.5)
P 		313.7
(-1)
P 		338.4
(-0.5)
P 		202.8
(-3)
P 		326
avr 631.4
(3) 		478.1
(0.5) 		337
(-1.8) 		293.9
(-2.5) 		371.5
(-1.2) 		261.5
(-3) 		370
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 176
1 2 3 4 range
A 199.7
(3)
P 		65.3
(-1.6)
P 		95.2
(-0.6)
P 		24.2
(-3)
P 		176
B 141.3
(3)
P 		70.6
(-1.5)
P 		82.8
(-0.7)
P 		47.5
(-3)
P 		94
C 179.1
(3)
P 		106.6
(-0.1)
P 		129.7
(0.9)
P 		40.3
(-3)
P 		139
avr 173.4
(3) 		80.8
(-1.1) 		102.6
(-0.1) 		37.3
(-3) 		136

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 194
1 2 3 4 5 6 range
A 119.6
(0.8)
P 		155.5
(3)
P 		78.9
(-1.6)
P 		55.5
(-3)
P 		137
(1.9)
P 		60.3
(-2.7)
P 		100
B 249.3
(3)
P 		181.3
(0.5)
P 		89
(-3)
P 		92.5
(-2.9)
P 		130.9
(-1.4)
P 		124.5
(-1.7)
P 		160
C 196
(3)
P 		138
(0.4)
P 		71.8
(-2.6)
P 		63.1
(-3)
P 		109.5
(-0.9)
P 		67.9
(-2.8)
P 		133
avr 188.3
(3) 		158.3
(1.5) 		79.9
(-2.5) 		70.4
(-3) 		125.8
(-0.2) 		84.2
(-2.3) 		118
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173906_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24660
Sequence Type Exemplar sequence
Representative Public ID CEK035F1R NCBI
Target Description CEK035F1R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=Y37A1B.15 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D33754 /WB_GENE_ID=Y37A1B.15 /WP=CE24205 /CHR=4 /FEA=Genomic Cluster /GEN=gei-18 /DEF=Src homology domain 3; C.elegans cDNA clone yk35f1 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070280(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070280 NCBI Caenorhabditis elegans GEX Interacting protein family member (gei-18) (gei-18) mRNA, complete cds. 11/11 None
Y37A1B.15 ENSEMBL cdna:known chromosome:CEL140:IV:13964340:13982492:-1 gene:Y37A1B.15 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13964356-13976709(-) 99.79 100.0
Public Domain and Genome References
Gene Title Src homology domain 3
Gene Symbol gei-18
Ensembl Y37A1B.15
Entrez Gene 178357 Entrez gene
SwissProt Q9TVW6 EMBL-EBI
WormBase CE36232 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB05124 Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] emb|CAA19497.3| Hypothetical protein Y37A1B.15 [Caenorhabditis elegans] ref|NP_502681.2| GEX Interacting protein family member (gei-18) [Caenorhabditis elegans] 0.0
blast T26607 hypothetical protein Y37A1B.14 - Caenorhabditis elegans 0.0
blast CAE74661 Hypothetical protein CBG22462 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001452 EMBL-EBI SH3 5.7E-12
Pfam IPR001452 EMBL-EBI SH3 1.7E-11
Pfam IPR001452 EMBL-EBI SH3 1.9E-9
Pfam IPR000219 EMBL-EBI DH domain 1.5E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502681.2 2 78-97,1752-1774
Y37A1B.15 2 78-97,1752-1774
Sequence
Target Sequence 
>C. ELEGANS:173906_AT
cttactatcttttgaatattgccaagttttatcccgatacatttctaaagaacctagtcg
taataggccaaaattttatcattttctgaatcaagccgcccatctttttatgaaattttc
cccccatttctgatcaacccgggttctcactttggtgctcatattcagaaacttaagtac
attttattgttttaagatgttttcccgttccagaaattcccagtttagtacacatatttc
ttctcgatatttacttattgcatgttttcagttatatatctcctttggccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTTACTATCTTTTGAATATTGCCAA 553 219 3011 Antisense
ATATTGCCAAGTTTTATCCCGATAC 13 19 3026 Antisense
TATCCCGATACATTTCTAAAGAACC 507 655 3040 Antisense
TTATCATTTTCTGAATCAAGCCGCC 175 681 3086 Antisense
CCCATTTCTGATCAACCCGGGTTCT 482 259 3133 Antisense
GGTTCTCACTTTGGTGCTCATATTC 361 507 3152 Antisense
TAAGATGTTTTCCCGTTCCAGAAAT 625 631 3203 Antisense
GTTTAGTACACATATTTCTTCTCGA 514 447 3233 Antisense
TTCTTCTCGATATTTACTTATTGCA 221 691 3248 Antisense
ACTTATTGCATGTTTTCAGTTATAT 338 103 3263 Antisense
TTCAGTTATATATCTCCTTTGGCCC 142 687 3277 Antisense
Sequence Source Affymetrix Proprietary Database