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[173898_at] protein disulfide-isomerase

Description AV194558 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=B0403.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV194558 /WB_GENE_ID=B0403.4 /WP=CE03880 /CHR=X /FEA=Genomic Cluster /DEF=protein disulfide-isomerase; Caenorhabditis elegans cDNA clone:yk630h5 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 01      4grp_highest_8_8 > 17      4grp_high_8_8 > 61      6grp_highest_nonorm > 06      6grp_total > 04      4grp_total > 58      6grp_cgc > 70      6grp_high1_sub > De      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12434
1 2 3 4 range
A 10882.5
(-0.6)
P 		13131.8
(0.6)
P 		17734.6
(3)
P 		6287.8
(-3)
P 		11447
B 12098.9
(-0.4)
P 		15964.8
(1.6)
P 		18721.8
(3)
P 		7052.7
(-3)
P 		11669
C 10731.8
(-0.4)
P 		14904.1
(3)
P 		14112.8
(2.4)
P 		7546.9
(-3)
P 		7357
avr 11237.7
(-0.4) 		14666.9
(1.7) 		16856.4
(3) 		6962.5
(-3) 		9894

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8350
1 2 3 4 5 6 range
A 12959.6
(3)
P 		11045.9
(1)
P 		11162.6
(1.1)
P 		9699.9
(-0.4)
P 		9405.4
(-0.8)
P 		7283
(-3)
P 		5677
B 11205.9
(3)
P 		10385.6
(2.1)
P 		10802.3
(2.6)
P 		10973.6
(2.7)
P 		8457.2
(0)
P 		5707
(-3)
P 		5499
C 14057
(3)
P 		10006.4
(-0.1)
P 		10619.1
(0.3)
P 		8755.9
(-1.1)
P 		10655.9
(0.4)
P 		6341
(-3)
P 		7716
avr 12740.8
(3) 		10479.3
(0.8) 		10861.3
(1.2) 		9809.8
(0.2) 		9506.2
(-0.1) 		6443.7
(-3) 		6297
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3998
1 2 3 4 range
A 3962.3
(1.9)
P 		2850.6
(0.1)
P 		4636.2
(3)
P 		920.4
(-3)
P 		3716
B 3858.2
(2)
P 		3942.9
(2.2)
P 		4338.3
(3)
P 		1502.9
(-3)
P 		2835
C 3552.5
(0.8)
P 		4285
(2)
P 		4918.8
(3)
P 		1272.5
(-3)
P 		3646
avr 3791
(1.5) 		3692.8
(1.3) 		4631.1
(3) 		1231.9
(-3) 		3399

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3450
1 2 3 4 5 6 range
A 2389
(-1.3)
P 		3928.5
(3)
P 		2431
(-1.2)
P 		2460.1
(-1.1)
P 		2838.1
(-0)
P 		1773.2
(-3)
P 		2155
B 3899.1
(3)
P 		3456.9
(1.5)
P 		2623.1
(-1.3)
P 		2906.5
(-0.4)
P 		3436.1
(1.4)
P 		2128.1
(-3)
P 		1771
C 5210.3
(3)
P 		3053.3
(-0.8)
P 		2702.7
(-1.4)
P 		1760.8
(-3)
P 		3448.1
(-0.1)
P 		2122.7
(-2.4)
P 		3450
avr 3832.8
(3) 		3479.6
(1.8) 		2585.6
(-1.1) 		2375.8
(-1.8) 		3240.8
(1.1) 		2008
(-3) 		1825
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173898_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25990
Sequence Type Exemplar sequence
Representative Public ID AV194558 NCBI
Target Description AV194558 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=B0403.4 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV194558 /WB_GENE_ID=B0403.4 /WP=CE03880 /CHR=X /FEA=Genomic Cluster /DEF=protein disulfide-isomerase; Caenorhabditis elegans cDNA clone:yk630h5 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076789(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076789 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-320) (tag-320) mRNA, complete cds. 11/11 None
B0403.4 ENSEMBL cdna:known chromosome:CEL140:X:7066292:7068510:-1 gene:B0403.4 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000026989 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7066322-7068387(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein disulfide-isomerase
Gene Symbol tag-320
Ensembl B0403.4
Entrez Gene 180974 Entrez gene
SwissProt Q11067 EMBL-EBI
WormBase CE03880 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261167_AT thioredoxin family protein at
CANINE:1583126_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFA.20823.1.S1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFA.5563.1.A1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFAAFFX.6163.1.S1_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFAAFFX.6163.1.S1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
DROSOPHILA_2:1626196_AT dm
DROSGENOME1:154419_AT dm
CHICKEN:GGAAFFX.24959.1.S1_AT protein disulfide isomerase family A, member 6 gga
HG-U133_PLUS_2:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-FOCUS:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:208638_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:208638_AT protein disulfide isomerase family A, member 6 hs
HG-FOCUS:208638_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:208638_AT protein disulfide isomerase family A, member 6 hs
HUGENEFL:Z22551_AT protein disulfide isomerase family A, member 6 hs
HUGENEFL:D49489_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:G4826813_3P_X_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:G4826813_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.211577.1.S1_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.182429.2.S1_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.182429.1.S2_3P_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:32846_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:41750_AT protein disulfide isomerase family A, member 6 hs
HG-U95D:74808_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:41751_AT protein disulfide isomerase family A, member 6 hs
HG-U95D:79104_R_AT Protein disulfide isomerase family A, member 6 hs
MOUSE430_2:1423648_AT protein disulfide isomerase associated 6 mm
MOUSE430A_2:1423648_AT protein disulfide isomerase associated 6 mm
MOE430A:1423648_AT protein disulfide isomerase associated 6 mm
MU11KSUBA:AA103744_F_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94207_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94209_G_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94208_AT protein disulfide isomerase associated 6 mm
MOE430A:1430983_AT protein disulfide isomerase associated 6 mm
MOUSE430A_2:1430983_AT protein disulfide isomerase associated 6 mm
MOUSE430_2:1430983_AT protein disulfide isomerase associated 6 mm
MU19KSUBA:TC18649_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
MU19KSUBB:TC32907_S_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
MU19KSUBC:TC41849_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
RT-U34:RC_AA892532_AT thioredoxin domain containing 7 rn
RG-U34A:RC_AA892532_AT thioredoxin domain containing 7 rn
RAE230A:1370859_AT thioredoxin domain containing 7 rn
RAT230_2:1370859_AT thioredoxin domain containing 7 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
16853 isomerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC47065 Temporarily assigned gene name protein 320 [Caenorhabditis elegans] ref|NP_509190.1| Temporarily Assigned Gene name family member (tag-320) [Caenorhabditis elegans] sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor 0.0
blast CAE65837 Hypothetical protein CBG10962 [Caenorhabditis briggsae] 0.0
blast AAF53532 CG5809-PA [Drosophila melanogaster] ref|NP_609792.1| CG5809-PA [Drosophila melanogaster] gb|AAL28897.1| LD28038p [Drosophila melanogaster] gb|AAF45013.1| symbol=BG:DS09218.4; cDNA=method:''sim4'', score:''1000.0'', desc:''LD05503 LD Drosophila melanogaster embryo BlueScript Drosophila melanogaster cDNA clone, full length mRNA sequence from BDGP''; match=method:''BLASTX'', version:''2.0a19MP-WashU [05-Feb-1998] [Build sol2.5-ultra 01:47:30 05-Feb-1998]'', score:''1420.0'', desc:''SwissProt::Q11067:PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR (EC 5.3.4.1). organism:CAENORHABDITIS ELEGANS. dbxref:EMBL; U40411; g1065461; -. WORMPEP; B0403.4; CE03880. PROS> 1.0E-140
Protein Domains
Database ID Description E-Value
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 1.1E-39
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 6.1E-44
Sequence
Target Sequence 
>C. ELEGANS:173898_AT
aaatcatgaattttctacatacatcgacaccaaaaacttactctcaccatgcaattttgt
tttaattgtaacgggtgttctcaccagataactcgtctaactgcgttacatccataca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATCATGAATTTTCTACATACATC 447 117 1336 Antisense
ATTTTCTACATACATCGACACCAAA 355 15 1345 Antisense
TCGACACCAAAAACTTACTCTCACC 160 601 1359 Antisense
CCAAAAACTTACTCTCACCATGCAA 17 273 1365 Antisense
TACTCTCACCATGCAATTTTGTTTT 341 645 1374 Antisense
CTCACCATGCAATTTTGTTTTAATT 337 229 1378 Antisense
GTAACGGGTGTTCTCACCAGATAAC 307 461 1403 Antisense
TTCTCACCAGATAACTCGTCTAACT 365 691 1413 Antisense
ACCAGATAACTCGTCTAACTGCGTT 195 87 1418 Antisense
AACTCGTCTAACTGCGTTACATCCA 70 141 1425 Antisense
CGTCTAACTGCGTTACATCCATACA 261 245 1429 Antisense
Sequence Source Affymetrix Proprietary Database