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[173876_s_at] Alcohol dehydrogenase

Description CEK130F7F /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=C17G10.8 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D68379 /WB_GENE_ID=C17G10.8 /WP=CE02490 /CHR=2 /FEA=Genomic Cluster /GEN=fat-3 /DEF=Alcohol dehydrogenase; C.elegans cDNA clone yk130f7 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 65      4grp_highest_8_8 > 22      4grp_high_8_8 > 07      6grp_highest_nonorm > 77      6grp_total > 57      4grp_total > 0      6grp_highest_sub > Cu      6grp_cgc > 36      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 343
1 2 3 4 range
A 1046
(-3)
P 		1252
(3)
P 		1147.1
(-0.1)
P 		1209.5
(1.8)
P 		206
B 1255.1
(1.3)
P 		1010.5
(-3)
P 		1135.7
(-0.8)
P 		1353.1
(3)
P 		343
C 1091.2
(-0.3)
P 		1049.1
(-3)
P 		1124.6
(1.9)
P 		1141
(3)
P 		92
avr 1130.8
(-1.8) 		1103.9
(-3) 		1135.8
(-1.5) 		1234.5
(3) 		131

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1146
1 2 3 4 5 6 range
A 1895.8
(3)
P 		975
(-3)
P 		1430
(-0)
P 		1310.8
(-0.8)
P 		1157.6
(-1.8)
P 		1680.5
(1.6)
P 		921
B 1664.3
(0.8)
P 		1119
(-2.8)
P 		1984.7
(2.9)
P 		1385.8
(-1.1)
P 		1088.8
(-3)
P 		2005.3
(3)
P 		917
C 1481.1
(0)
P 		1263.9
(-1.1)
P 		1543.9
(0.4)
P 		1480.4
(0)
P 		899.2
(-3)
P 		2045
(3)
P 		1146
avr 1680.4
(1.4) 		1119.3
(-2.5) 		1652.9
(1.2) 		1392.3
(-0.6) 		1048.5
(-3) 		1910.3
(3) 		862
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 223
1 2 3 4 range
A 380.8
(3)
P 		271.8
(-0.2)
P 		299.9
(0.6)
P 		177
(-3)
P 		204
B 400.2
(3)
P 		249.6
(-3)
P 		263.2
(-2.5)
P 		288.3
(-1.5)
P 		151
C 361.2
(2.1)
P 		301.6
(0.3)
P 		391.9
(3)
P 		192.4
(-3)
P 		200
avr 380.7
(3) 		274.3
(-1) 		318.3
(0.7) 		219.2
(-3) 		162

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 457
1 2 3 4 5 6 range
A 349.5
(-0.7)
P 		346.7
(-0.8)
P 		311.4
(-3)
P 		332.5
(-1.7)
P 		349.3
(-0.7)
P 		409.2
(3)
P 		98
B 579.1
(0.3)
P 		372.5
(-2.9)
P 		481.9
(-1.2)
P 		367.1
(-3)
P 		442.4
(-1.8)
P 		747.8
(3)
P 		381
C 549
(0.9)
P 		385.6
(-1.6)
P 		392.9
(-1.4)
P 		297.7
(-2.9)
P 		291
(-3)
P 		684.6
(3)
P 		394
avr 492.5
(0.4) 		368.3
(-2.2) 		395.4
(-1.7) 		332.4
(-3) 		360.9
(-2.4) 		613.9
(3) 		282
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173876_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23714
Sequence Type Exemplar sequence
Representative Public ID CEK130F7F NCBI
Target Description CEK130F7F /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=C17G10.8 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D68379 /WB_GENE_ID=C17G10.8 /WP=CE02490 /CHR=2 /FEA=Genomic Cluster /GEN=fat-3 /DEF=Alcohol dehydrogenase; C.elegans cDNA clone yk130f7 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026801(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026801 NCBI Caenorhabditis elegans DeHydrogenases, Short chain family member (dhs-6) (dhs-6) mRNA, complete cds. 11/11 None
C17G10.8 ENSEMBL cdna:known chromosome:CEL140:II:5617103:5619288:-1 gene:C17G10.8 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000018057 6/11 Cross Hyb Matching Probes None
GENEFINDER00000018084 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5617129-5622449(-) 100.0 100.0
Public Domain and Genome References
Gene Title Alcohol dehydrogenase
Gene Symbol dhs-6
Ensembl C17G10.8
Entrez Gene 3565470 Entrez gene
SwissProt Q09979 EMBL-EBI
WormBase CE02490 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1606092_AT similar to hydroxysteroid dehydrogenase like 2 cfa
CANINE:1588525_AT similar to hydroxysteroid dehydrogenase like 2 cfa
CANINE:1587573_AT similar to hydroxysteroid dehydrogenase like 2 cfa
CANINE_2:CFA.10807.1.S1_AT similar to hydroxysteroid dehydrogenase like 2 cfa
CANINE_2:CFAAFFX.5502.1.S1_S_AT similar to hydroxysteroid dehydrogenase like 2 cfa
DROSOPHILA_2:1628432_AT dm
DROSGENOME1:151807_AT dm
HG-U133A:209512_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133_PLUS_2:209512_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133A_2:209512_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133A:209513_S_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133_PLUS_2:209513_S_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133A_2:209513_S_AT hydroxysteroid dehydrogenase like 2 hs
HU35KSUBA:AA402006_AT hydroxysteroid dehydrogenase like 2 hs
HU35KSUBA:AA305116_AT hydroxysteroid dehydrogenase like 2 hs
HU35KSUBC:RC_N52938_AT hydroxysteroid dehydrogenase like 2 hs
HU35KSUBC:RC_AA398474_S_AT hydroxysteroid dehydrogenase like 2 hs
U133_X3P:G13279253_3P_S_AT hydroxysteroid dehydrogenase like 2 hs
U133_X3P:HS2.421785.1.S1_3P_X_AT hydroxysteroid dehydrogenase like 2 hs
U133_X3P:HS2.421785.1.S1_3P_AT hydroxysteroid dehydrogenase like 2 hs
U133_X3P:1559128_3P_AT hydroxysteroid dehydrogenase like 2 hs
HG-U133_PLUS_2:1559128_AT hydroxysteroid dehydrogenase like 2 hs
HG-U95B:41895_AT Hydroxysteroid dehydrogenase like 2 hs
HU35KSUBC:RC_W93497_AT Hydroxysteroid dehydrogenase like 2 hs
U133_X3P:HS2.59486.1.S1_3P_S_AT Hydroxysteroid dehydrogenase like 2 hs
U133_X3P:HS2.59486.1.S1_3P_AT Hydroxysteroid dehydrogenase like 2 hs
U133_X3P:1557517_3P_A_AT Hydroxysteroid dehydrogenase like 2 hs
HG-U133_PLUS_2:1557517_A_AT Hydroxysteroid dehydrogenase like 2 hs
HG-U95D:71219_AT Hydroxysteroid dehydrogenase like 2 hs
MG-U74AV2:96095_I_AT hydroxysteroid dehydrogenase like 2 mm
MG-U74AV2:96096_F_AT hydroxysteroid dehydrogenase like 2 mm
MOE430A:1426857_A_AT hydroxysteroid dehydrogenase like 2 mm
MOUSE430A_2:1426857_A_AT hydroxysteroid dehydrogenase like 2 mm
MOUSE430_2:1426857_A_AT hydroxysteroid dehydrogenase like 2 mm
MOE430A:1426856_AT hydroxysteroid dehydrogenase like 2 mm
MOUSE430A_2:1426856_AT hydroxysteroid dehydrogenase like 2 mm
MOUSE430_2:1426856_AT hydroxysteroid dehydrogenase like 2 mm
MG-U74BV2:164471_F_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
MG-U74CV2:170706_R_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
MU19KSUBB:TC29850_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
MU19KSUBB:TC29850_G_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
MU19KSUBC:TC35366_I_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
MU19KSUBC:TC37594_AT Hydroxysteroid dehydrogenase like 2 (Hsdl2), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5498 sterol carrier activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK68187 Dehydrogenases, short chain protein 6 [Caenorhabditis elegans] ref|NP_001021972.1| DeHydrogenases, Short chain family member (dhs-6) [Caenorhabditis elegans] 0.0
blast T34105 hypothetical protein C17G10.8 - Caenorhabditis elegans 0.0
blast CAE62784 Hypothetical protein CBG06955 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.5E-34
Pfam IPR003033 EMBL-EBI Sterol-binding 1.8E-45
Sequence
Target Sequence 
>C. ELEGANS:173876_S_AT
catgtgtgccagatgctccattgatgcccgatttctttattcctgcaggaacttacgatc
acaagttctcatctggagcacagatcggaaaaaagaataagactcacgaagccggagttg
ttgaagaagagatcaaacagatattcacatctgcaaagcgcctgcttaatgctgatattg
taaagaaaactggattcgtgtatgaattcttgttaaaagacccaactacaaaaagcgaga
gaatcattactttggacttgaaaaacggagaaggagcactgacagataagaaggcttcag
gcaaagctgatgttaaattcacacttgctccagaacatttcgctccactcttcactggaa
aactccgtccgacgactgctctgatgacaaagaagctccaaatctccggtgatatgccag
gagcaatgaaattggagagccttctccgcaagttcaccgaagg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATGTGTGCCAGATGCTCCATTGAT 212 209 2358 Antisense
ATTGATGCCCGATTTCTTTATTCCT 566 5 2377 Antisense
TTCCTGCAGGAACTTACGATCACAA 602 699 2397 Antisense
ACGATCACAAGTTCTCATCTGGAGC 1 95 2412 Antisense
GATATTCACATCTGCAAAGCGCCTG 385 427 2497 Antisense
AAAGCGCCTGCTTAATGCTGATATT 200 125 2512 Antisense
GATGTTAAATTCACACTTGCTCCAG 694 409 2666 Antisense
TCCACTCTTCACTGGAAAACTCCGT 542 587 2701 Antisense
GTCCGACGACTGCTCTGATGACAAA 163 477 2724 Antisense
GAAGCTCCAAATCTCCGGTGATATG 322 343 2749 Antisense
GCCTTCTCCGCAAGTTCACCGAAGG 376 281 2796 Antisense
Sequence Source Affymetrix Proprietary Database