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[173873_at] Human host cell factor C1 like protein

Description C66173 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F53E4.1 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C66173 /WB_GENE_ID=F53E4.1 /WP=CE20848 /CHR=5 /FEA=Genomic Cluster /DEF=Human host cell factor C1 like protein; C.elegans cDNA clone yk205a3 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 05      4grp_high_8_8 > 30      6grp_highest_nonorm > 78      6grp_total > 89      4grp_total > 33      6grp_highest_sub > Cu      6grp_high1_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1057
1 2 3 4 range
A 1431
(-3)
P 		1660.6
(0)
P 		1808
(1.9)
P 		1888.4
(3)
P 		457
B 1496.7
(-3)
P 		2023.5
(1.3)
P 		2175.3
(2.5)
P 		2232.9
(3)
P 		736
C 1312.4
(-3)
P 		2369.1
(3)
P 		1868.1
(0.2)
P 		2132.1
(1.7)
P 		1057
avr 1413.4
(-3) 		2017.7
(2.4) 		1950.5
(1.8) 		2084.5
(3) 		671

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1451
1 2 3 4 5 6 range
A 1555.1
(0.4)
P 		1176.6
(-1.4)
P 		818.4
(-3)
P 		901.3
(-2.6)
P 		2083.8
(2.8)
P 		2125.9
(3)
P 		1308
B 1694.2
(1.1)
P 		1135.6
(-2)
P 		944.2
(-3)
P 		1386.1
(-0.6)
P 		1993.5
(2.7)
P 		2051.4
(3)
P 		1107
C 1463.3
(-0.6)
P 		1082.7
(-2.3)
P 		937.9
(-3)
P 		1187.2
(-1.9)
P 		1593.5
(-0)
P 		2269.2
(3)
P 		1331
avr 1570.9
(0.2) 		1131.6
(-1.9) 		900.2
(-3) 		1158.2
(-1.8) 		1890.3
(1.8) 		2148.8
(3) 		1249
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 405
1 2 3 4 range
A 521
(3)
P 		360.5
(-0.9)
P 		472.7
(1.8)
P 		276.4
(-3)
P 		245
B 477.3
(-2.7)
P 		499.8
(2.1)
P 		504.1
(3)
P 		475.8
(-3)
P 		28
C 434.4
(-1.6)
P 		681.1
(3)
P 		651.1
(2.4)
P 		359.5
(-3)
P 		322
avr 477.6
(0.7) 		513.8
(2) 		542.6
(3) 		370.6
(-3) 		172

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 632
1 2 3 4 5 6 range
A 286.7
(-1.6)
P 		418.5
(0.2)
P 		178.2
(-3)
P 		228.6
(-2.3)
P 		628.8
(3)
P 		517.6
(1.5)
P 		451
B 589.5
(0.7)
P 		378
(-1.5)
P 		229.3
(-3)
P 		367.1
(-1.6)
P 		809.9
(3)
P 		765
(2.5)
P 		581
C 542.4
(0.5)
P 		330.4
(-1.9)
P 		238.7
(-3)
P 		238.7
(-3)
P 		515.6
(0.2)
P 		759.6
(3)
P 		521
avr 472.9
(0.3) 		375.6
(-0.9) 		215.4
(-3) 		278.1
(-2.2) 		651.4
(2.6) 		680.7
(3) 		465
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173873_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25411
Sequence Type Exemplar sequence
Representative Public ID C66173 NCBI
Target Description C66173 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F53E4.1 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C66173 /WB_GENE_ID=F53E4.1 /WP=CE20848 /CHR=5 /FEA=Genomic Cluster /DEF=Human host cell factor C1 like protein; C.elegans cDNA clone yk205a3 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074494(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074494 NCBI Caenorhabditis elegans F53E4.1 (F53E4.1) mRNA, complete cds. 11/11 None
F53E4.1 ENSEMBL cdna:known chromosome:CEL140:V:15655082:15661651:-1 gene:F53E4.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15655092-15661646(-) 98.65 100.0
Public Domain and Genome References
Gene Title Human host cell factor C1 like protein
Ensembl F53E4.1
Entrez Gene 180050 Entrez gene
SwissProt O17718 EMBL-EBI
WormBase CE20848 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:255769_AT kelch repeat-containing protein at
CANINE:1583568_AT similar to kelch domain containing 3 (predicted) cfa
CANINE:1584537_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.16400.1.A1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.18469.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFA.3935.1.A1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3548.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3553.1.S1_AT similar to kelch domain containing 3 (predicted) cfa
CANINE_2:CFAAFFX.3554.1.S1_S_AT similar to kelch domain containing 3 (predicted) cfa
DROSOPHILA_2:1626154_AT dm
DROSGENOME1:153965_AT dm
CHICKEN:GGA.15874.1.S1_AT kelch domain containing 3 gga
HG-U133A:208784_S_AT kelch domain containing 3 hs
HG-U133_PLUS_2:208784_S_AT kelch domain containing 3 hs
HG-U133A_2:208784_S_AT kelch domain containing 3 hs
HUGENEFL:X98248_RNA1_AT kelch domain containing 3 hs
U133_X3P:G12804724_3P_X_AT kelch domain containing 3 hs
U133_X3P:HS.281706.2.S1_3P_A_AT kelch domain containing 3 hs
HG-U133A_2:214383_X_AT kelch domain containing 3 hs
HG-U133_PLUS_2:214383_X_AT kelch domain containing 3 hs
HG-U133A:214383_X_AT kelch domain containing 3 hs
HG-U95AV2:39537_AT kelch domain containing 3 hs
HG-U95D:82804_AT kelch domain containing 3 hs
MOE430A:1448164_AT kelch domain containing 3 mm
MOUSE430A_2:1448164_AT kelch domain containing 3 mm
MOUSE430_2:1448164_AT kelch domain containing 3 mm
MOUSE430_2:1415991_A_AT kelch domain containing 3 mm
MOUSE430A_2:1415991_A_AT kelch domain containing 3 mm
MOE430A:1415991_A_AT kelch domain containing 3 mm
MOUSE430A_2:1455910_AT kelch domain containing 3 mm
MOE430A:1455910_AT kelch domain containing 3 mm
MOUSE430_2:1455910_AT kelch domain containing 3 mm
MOE430A:1454747_A_AT kelch domain containing 3 mm
MOUSE430A_2:1454747_A_AT kelch domain containing 3 mm
MOUSE430_2:1454747_A_AT kelch domain containing 3 mm
MU19KSUBC:TC37515_AT Kelch domain containing 3, mRNA (cDNA clone MGC:25567 IMAGE:3983436) mm
Protein Similarities
Method ID Description E-Value
blast CAB04012 Hypothetical protein F53E4.1 [Caenorhabditis elegans] emb|CAB03122.1| Hypothetical protein F53E4.1 [Caenorhabditis elegans] ref|NP_506895.1| F53E4.1 [Caenorhabditis elegans] 0.0
blast CAE61037 Hypothetical protein CBG04780 [Caenorhabditis briggsae] 0.0
blast AAI03003 Kelch domain containing 3 [Bos taurus] ref|NP_001014966.1| kelch domain containing 3 [Bos taurus] gb|AAX08673.1| testis intracellular mediator protein [Bos taurus] 2.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR006652 EMBL-EBI Kelch repeat 9.7E-6
Pfam IPR006652 EMBL-EBI Kelch repeat 4.7E-6
Pfam IPR006652 EMBL-EBI Kelch repeat 7.2E-8
Pfam IPR006652 EMBL-EBI Kelch repeat 1.7E-4
Pfam IPR006652 EMBL-EBI Kelch repeat 5.8E-7
Pfam IPR006652 EMBL-EBI Kelch repeat 3.7E-4
Sequence
Target Sequence 
>C. ELEGANS:173873_AT
aatattttctatcctgtaactcatgtgtaactaagatttctttcgccgccttctaaccat
tttctttcgctttttaaccggattttatccccaaccattcaatcgggtatcactactgtt
gttttcttttttgtctcttttcgttgaattttccccaaatttccaggtttctagatcttg
ttttgtctgtacattgcccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATATTTTCTATCCTGTAACTCATG 324 173 1338 Antisense
TTCTATCCTGTAACTCATGTGTAAC 364 691 1344 Antisense
TCCTGTAACTCATGTGTAACTAAGA 216 593 1349 Antisense
TAACTAAGATTTCTTTCGCCGCCTT 348 515 1365 Antisense
GGATTTTATCCCCAACCATTCAATC 417 509 1417 Antisense
ATCCCCAACCATTCAATCGGGTATC 99 39 1424 Antisense
TTCAATCGGGTATCACTACTGTTGT 642 679 1435 Antisense
GGGTATCACTACTGTTGTTTTCTTT 89 497 1442 Antisense
ATCACTACTGTTGTTTTCTTTTTTG 636 23 1446 Antisense
TTCCAGGTTTCTAGATCTTGTTTTG 398 699 1498 Antisense
TCTTGTTTTGTCTGTACATTGCCCC 380 617 1513 Antisense
Sequence Source Affymetrix Proprietary Database