[Home] | [Total List]

[173831_s_at] guanylate cyclase

Description CEK041F4R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK896.8 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D34144 /WB_GENE_ID=ZK896.8 /WP=CE15463 /CHR=4 /FEA=Genomic Cluster /GEN=gcy-26 /DEF=guanylate cyclase; C.elegans cDNA clone yk41f4 : 3prime end, single read.
Cluster 6grp_total > 14      4grp_total > 47      6grp_cgc > 30      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 130
1 2 3 4 range
A 127.5
(3)
P 		14.2
(-3)
A 		49
(-1.2)
A 		80.7
(0.5)
A 		113
B 99.4
(3)
M 		71.1
(-1.9)
A 		86.5
(0.8)
A 		64.7
(-3)
A 		35
C 144.1
(3)
P 		68.8
(-0.9)
A 		28.9
(-3)
A 		48.1
(-2)
A 		115
avr 123.7
(3) 		51.4
(-3) 		54.8
(-2.7) 		64.5
(-1.9) 		72

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 145
1 2 3 4 5 6 range
A 175.5
(3)
P 		133.4
(1.3)
P 		68.9
(-1.4)
P 		120.9
(0.7)
P 		31
(-3)
A 		45.9
(-2.4)
A 		145
B 169.2
(3)
P 		118.2
(0.6)
P 		104.1
(-0)
P 		109.2
(0.2)
P 		67.3
(-1.7)
A 		39.3
(-3)
A 		130
C 167.7
(3)
P 		150.2
(2.1)
P 		111.6
(0.3)
M 		104.5
(-0.1)
A 		59.1
(-2.3)
A 		44.7
(-3)
A 		123
avr 170.8
(3) 		133.9
(1.3) 		94.9
(-0.6) 		111.5
(0.2) 		52.5
(-2.6) 		43.3
(-3) 		128
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 45
1 2 3 4 range
A 46.4
(3)
P 		3.1
(-3)
A 		12.8
(-1.7)
A 		11.8
(-1.8)
A 		43
B 31.7
(3)
M 		17.6
(-1.7)
A 		20
(-0.9)
A 		13.8
(-3)
A 		18
C 47.7
(3)
P 		19.8
(-1.2)
A 		10.1
(-2.7)
A 		8.1
(-3)
A 		40
avr 41.9
(3) 		13.5
(-2.6) 		14.3
(-2.4) 		11.2
(-3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 53
1 2 3 4 5 6 range
A 32.3
(0.6)
P 		47.4
(3)
P 		15
(-2.1)
P 		30.7
(0.4)
P 		9.4
(-3)
A 		11.2
(-2.7)
A 		38
B 58.9
(3)
P 		39.4
(0.4)
P 		25.3
(-1.6)
P 		28.9
(-1.1)
P 		27.3
(-1.3)
A 		14.7
(-3)
A 		44
C 62.2
(3)
P 		45.8
(0.9)
P 		28.4
(-1.3)
M 		21
(-2.2)
A 		19.1
(-2.5)
A 		15
(-3)
A 		47
avr 51.1
(3) 		44.2
(1.9) 		22.9
(-1.5) 		26.9
(-0.9) 		18.6
(-2.2) 		13.6
(-3) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173831_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24673
Sequence Type Exemplar sequence
Representative Public ID CEK041F4R NCBI
Target Description CEK041F4R_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK896.8 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D34144 /WB_GENE_ID=ZK896.8 /WP=CE15463 /CHR=4 /FEA=Genomic Cluster /GEN=gcy-26 /DEF=guanylate cyclase; C.elegans cDNA clone yk41f4 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070048(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070048 NCBI Caenorhabditis elegans Guanylyl CYclase family member (gcy-18) (gcy-18) mRNA, complete cds. 11/11 None
SNAP00000024383 ENSEMBL cdna:SNAP chromosome:CEL140:IV:12860107:12865581:1 11/11 None
GENEFINDER00000024391 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:12855527:12865581:1 11/11 None
ZK896.8 ENSEMBL cdna:known chromosome:CEL140:IV:12860107:12865905:1 gene:ZK896.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12860113-12865588(+) 100.0 100.0
Public Domain and Genome References
Gene Title guanylate cyclase
Gene Symbol gcy-18
Ensembl ZK896.8
Entrez Gene 178237 Entrez gene
SwissProt O02344 EMBL-EBI
WormBase CE15463 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05325 Hypothetical protein ZK896.8 [Caenorhabditis elegans] ref|NP_502449.1| Guanylyl CYclase family member (gcy-18) [Caenorhabditis elegans] 0.0
blast CAE56618 Hypothetical protein CBG24374 [Caenorhabditis briggsae] 0.0
blast NP_500309 Guanylyl CYclase family member (gcy-23) [Caenorhabditis elegans] gb|AAC17555.3| Guanylyl cyclase protein 23 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.8E-10
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.0E-71
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.1E-60
Pfam IPR000719 EMBL-EBI Protein kinase 5.8E-10
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.0E-71
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.5E-60
Pfam IPR000719 EMBL-EBI Protein kinase 5.8E-10
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.0E-71
Pfam IPR007271 EMBL-EBI Nucleotide-sugar transporter 1.0E-126
Pfam IPR001828 EMBL-EBI Extracellular ligand-binding receptor 1.5E-60
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502449.1 1 497-519
ZK896.8 1 497-519
SNAP00000024383 1 498-520
GENEFINDER00000024391 11 13-32,88-106,111-133,138-155,168-190,210-232,245-264,290-309,316-338,343-362,893-915
Sequence
Target Sequence 
>C. ELEGANS:173831_S_AT
ggaagatctgttgctccgaagctttattcatcggcgacaattctattctcagatattgtc
ggattcactacaatatgctccggctcaactccactggaagttgtcaatatgcttaatggg
ctgtacactggatttgatgaatgtataactcggaataagagttacaaagtggaaactatc
ggagacgcttatatggttgtatctgggatccctgaagaaaatgaatataatcattcgagg
aacattgcgaatactgcactagacatgcgtcagtacctaaccggatatcaaattccacat
cgtccaacccatcgtgtccgttgtcgctggggattccatacaggatccgtcgccgccgga
gtcgtcgggttgacgtgtccaagatattgtctcttcggtgatactgtcaatgtttcgtca
agaatggaatcaactggaacgcctggaatgatccaaatgagtgaggaggctcatatgcac
attagagctcatcatccggtgtttacaacgactgaaagaggagaggttcaagtgaaagga
aagggcacttgcaggacattctggttggaggatcgagttggtgacgcctcgactacaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAAGATCTGTTGCTCCGAAGCTTT 259 531 2724 Antisense
CATCGGCGACAATTCTATTCTCAGA 627 211 2752 Antisense
TTCACTACAATATGCTCCGGCTCAA 706 685 2787 Antisense
ACATGCGTCAGTACCTAACCGGATA 644 105 2986 Antisense
ATATCAAATTCCACATCGTCCAACC 291 19 3008 Antisense
GGGGATTCCATACAGGATCCGTCGC 43 499 3052 Antisense
GGAGTCGTCGGGTTGACGTGTCCAA 416 515 3081 Antisense
GATATTGTCTCTTCGGTGATACTGT 418 427 3106 Antisense
TTAGAGCTCATCATCCGGTGTTTAC 387 681 3205 Antisense
GGGCACTTGCAGGACATTCTGGTTG 473 493 3266 Antisense
CGAGTTGGTGACGCCTCGACTACAA 227 249 3297 Antisense
Sequence Source Affymetrix Proprietary Database