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[173822_s_at] 59 protein

Description AV186449 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=C08B6.7 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV186449 /WB_GENE_ID=C08B6.7 /WP=CE05244 /CHR=5 /FEA=Genomic Cluster /DEF=59 protein; Caenorhabditis elegans cDNA clone:yk499f5 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 95      6grp_high1_10_10 > 68      4grp_highest_8_8 > 36      4grp_high_8_8 > 0      6grp_highest_nonorm > 91      6grp_total > 59      4grp_total > 31      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 164
1 2 3 4 range
A 286.7
(3)
P 		179.6
(-2.4)
P 		251
(1.2)
P 		166.7
(-3)
P 		120
B 329.6
(3)
P 		172.7
(-3)
P 		221.9
(-1.1)
P 		330.4
(3)
P 		158
C 289.5
(3)
P 		193.4
(-3)
P 		251.2
(0.6)
P 		230.9
(-0.7)
P 		96
avr 301.9
(3) 		181.9
(-3) 		241.4
(-0) 		242.7
(0) 		120

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 280
1 2 3 4 5 6 range
A 210.5
(-0.6)
P 		300.4
(1.3)
P 		216
(-0.5)
P 		102.8
(-3)
P 		248.1
(0.2)
P 		376.6
(3)
P 		274
B 273.3
(0.8)
P 		233.5
(-0.2)
P 		125.1
(-3)
P 		205
(-1)
P 		211.3
(-0.8)
P 		361.4
(3)
P 		236
C 313.9
(0.8)
P 		241.6
(-1.6)
P 		200.9
(-2.9)
P 		197.2
(-3)
P 		289.2
(-0)
P 		383.2
(3)
P 		186
avr 265.9
(-0.1) 		258.5
(-0.4) 		180.7
(-2.6) 		168.3
(-3) 		249.5
(-0.6) 		373.7
(3) 		205
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 81
1 2 3 4 range
A 104.4
(3)
P 		39
(-1.9)
P 		65.6
(0.1)
P 		24.4
(-3)
P 		80
B 105.1
(3)
P 		42.7
(-3)
P 		51.4
(-2.2)
P 		70.4
(-0.3)
P 		62
C 95.8
(3)
P 		55.6
(-1.2)
P 		87.6
(2.1)
P 		38.9
(-3)
P 		57
avr 101.8
(3) 		45.8
(-2.9) 		68.2
(-0.5) 		44.6
(-3) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 38.8
(-2.1)
P 		106.8
(3)
P 		47
(-1.4)
P 		26.1
(-3)
P 		74.9
(0.6)
P 		91.7
(1.9)
P 		81
B 95.1
(0.7)
P 		77.7
(-0.3)
P 		30.4
(-3)
P 		54.3
(-1.6)
P 		85.9
(0.2)
P 		134.8
(3)
P 		104
C 116.3
(2.2)
P 		73.7
(-0.7)
P 		51.1
(-2.2)
P 		39.7
(-3)
P 		93.6
(0.7)
P 		128.3
(3)
P 		89
avr 83.4
(0.3) 		86.1
(0.5) 		42.8
(-2.8) 		40
(-3) 		84.8
(0.4) 		118.3
(3) 		78
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173822_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25089
Sequence Type Exemplar sequence
Representative Public ID AV186449 NCBI
Target Description AV186449 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=C08B6.7 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV186449 /WB_GENE_ID=C08B6.7 /WP=CE05244 /CHR=5 /FEA=Genomic Cluster /DEF=59 protein; Caenorhabditis elegans cDNA clone:yk499f5 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073204(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073204 NCBI Caenorhabditis elegans C08B6.7 (C08B6.7) mRNA, complete cds. 11/11 None
C08B6.7.1 ENSEMBL cdna:known chromosome:CEL140:V:10132986:10136731:-1 gene:C08B6.7 11/11 None
C08B6.7.2 ENSEMBL cdna:known chromosome:CEL140:V:10132986:10136729:-1 gene:C08B6.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10133024-10136528(-) 100.0 100.0
Public Domain and Genome References
Gene Title 59 protein
Ensembl C08B6.7
Entrez Gene 179410 Entrez gene
SwissProt Q17818 EMBL-EBI
WormBase CE05244 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13924_AT transducin family protein / WD-40 repeat family protein at
ATH1-121501:265469_AT transducin family protein / WD-40 repeat family protein at
CANINE:1602649_AT similar to WD repeat domain 20 isoform 2 cfa
CANINE:1587457_AT similar to WD repeat domain 20 isoform 2 cfa
CANINE_2:CFA.10473.1.S1_S_AT similar to WD repeat domain 20 isoform 2 cfa
CANINE_2:CFAAFFX.27639.1.S1_S_AT similar to WD repeat domain 20 isoform 2 cfa
CHICKEN:GGA.5414.1.S1_AT similar to WD repeat domain 20 isoform 1 gga
CHICKEN:GGA.5414.3.S1_A_AT similar to WD repeat domain 20 isoform 1 gga
CHICKEN:GGAAFFX.7220.1.S1_AT similar to WD repeat domain 20 isoform 1 gga
HG-U133_PLUS_2:227541_AT WD repeat domain 20 hs
HG-U133B:227541_AT WD repeat domain 20 hs
HU35KSUBC:RC_N98926_AT WD repeat domain 20 hs
HU35KSUBC:RC_AA437270_AT WD repeat domain 20 hs
U133_X3P:HS2.283304.1.S1_3P_S_AT WD repeat domain 20 hs
U133_X3P:HS2.283304.1.S1_3P_AT WD repeat domain 20 hs
U133_X3P:HS.57637.0.A1_3P_AT WD repeat domain 20 hs
U133_X3P:HS.55209.0.S1_3P_AT WD repeat domain 20 hs
U133_X3P:1554549_3P_A_AT WD repeat domain 20 hs
HG-U133_PLUS_2:1554549_A_AT WD repeat domain 20 hs
HG-U133_PLUS_2:227693_AT WD repeat domain 20 hs
HG-U133B:227693_AT WD repeat domain 20 hs
HG-U95B:46100_AT WD repeat domain 20 hs
HG-U95B:53157_AT WD repeat domain 20 hs
HG-U95D:83063_AT WD repeat domain 20 hs
HG-U95E:85568_AT WD repeat domain 20 hs
HG-U95B:46339_AT WD repeat domain 20 hs
HG-U95D:88106_AT WD repeat domain 20 hs
HU35KSUBB:RC_N58054_AT WD repeat domain 20 hs
MU11KSUBA:AA623801_AT RIKEN cDNA 2310040A13 gene mm
MU11KSUBA:AA623801_G_AT RIKEN cDNA 2310040A13 gene mm
MG-U74AV2:104117_AT RIKEN cDNA 2310040A13 gene mm
MG-U74BV2:114133_AT RIKEN cDNA 2310040A13 gene mm
MOE430A:1451220_AT RIKEN cDNA 2310040A13 gene mm
MOUSE430A_2:1451220_AT RIKEN cDNA 2310040A13 gene mm
MOUSE430_2:1451220_AT RIKEN cDNA 2310040A13 gene mm
MOE430A:1449197_AT RIKEN cDNA 2310040A13 gene mm
MOUSE430A_2:1449197_AT RIKEN cDNA 2310040A13 gene mm
MOUSE430_2:1449197_AT RIKEN cDNA 2310040A13 gene mm
MG-U74CV2:136164_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOE430A:1431227_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOUSE430A_2:1431227_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOUSE430_2:1431227_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOUSE430_2:1428039_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOUSE430A_2:1428039_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MOE430A:1428039_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
MU19KSUBC:TC41080_AT RIKEN cDNA 2310040A13 gene, mRNA (cDNA clone MGC:30262 IMAGE:4221717) mm
RAE230A:1390661_AT WD repeat domain 20 (predicted) rn
RAT230_2:1390661_AT WD repeat domain 20 (predicted) rn
RAE230A:1373084_AT WD repeat domain 20 (predicted) rn
RAT230_2:1373084_AT WD repeat domain 20 (predicted) rn
RG-U34B:RC_AI010006_AT WD repeat domain 20 (predicted) rn
RG-U34C:RC_AI231333_AT WD repeat domain 20 (predicted) rn
RG-U34C:RC_AI145461_AT WD repeat domain 20 (predicted) rn
RAE230B:1395097_AT WD repeat domain 20 (predicted) rn
RAT230_2:1395097_AT WD repeat domain 20 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast CAA96589 Hypothetical protein C08B6.7 [Caenorhabditis elegans] ref|NP_505605.1| C08B6.7 [Caenorhabditis elegans] 0.0
blast CAE64739 Hypothetical protein CBG09527 [Caenorhabditis briggsae] 0.0
blast NP_851808 WD repeat domain 20 isoform 1 [Homo sapiens] 1.0E-116
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.14
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-4
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 6.7E-4
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0081
Sequence
Target Sequence 
>C. ELEGANS:173822_S_AT
cactccacttcgggtatcttaaattttctttactaggttcttattcttttttattgttca
cttaatcttatttattgtcgtcaagcgtaatgctctgatctttaggatgtatactgtaac
atgatttttctggattatttctaattgtaaagcccggcaaagttgtttgccattgtttgc
aaactatgatcacctgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACTCCACTTCGGGTATCTTAAATT 145 199 2268 Antisense
TTTATTGTTCACTTAATCTTATTTA 275 675 2317 Antisense
AATCTTATTTATTGTCGTCAAGCGT 32 171 2331 Antisense
GTCGTCAAGCGTAATGCTCTGATCT 389 473 2344 Antisense
GCGTAATGCTCTGATCTTTAGGATG 686 291 2352 Antisense
TATACTGTAACATGATTTTTCTGGA 192 659 2377 Antisense
ACATGATTTTTCTGGATTATTTCTA 334 107 2386 Antisense
TTATTTCTAATTGTAAAGCCCGGCA 300 1 2402 Antisense
AAGCCCGGCAAAGTTGTTTGCCATT 660 149 2417 Antisense
CAAAGTTGTTTGCCATTGTTTGCAA 140 193 2425 Antisense
TTGTTTGCAAACTATGATCACCTGC 484 705 2440 Antisense
Sequence Source Affymetrix Proprietary Database