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[173808_s_at] Kinesin motor domain

Description CEK035BYR_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=Y43F4B.6 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D33723 /WB_GENE_ID=Y43F4B.6 /WP=CE16631 /CHR=3 /FEA=Genomic Cluster /DEF=Kinesin motor domain; C.elegans cDNA clone yk35b11 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 87      6grp_high1_10_10 > 77      4grp_highest_8_8 > 09      4grp_high_8_8 > 53      6grp_highest_nonorm > 95      6grp_total > 78      4grp_total > 58      6grp_highest_sub > Da      6grp_cgc > 49      6grp_high1_sub > Da      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 540
1 2 3 4 range
A 422.1
(-1.4)
P 		785.3
(3)
P 		772.3
(2.8)
P 		290.9
(-3)
P 		494
B 510.4
(0.1)
P 		688
(3)
P 		686.9
(3)
P 		323.9
(-3)
P 		364
C 535.3
(-0.2)
P 		826.3
(3)
P 		693.7
(1.5)
P 		286.4
(-3)
P 		540
avr 489.3
(-0.6) 		766.5
(3) 		717.6
(2.4) 		300.4
(-3) 		466

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1325
1 2 3 4 5 6 range
A 562.7
(-2)
P 		502.5
(-2.3)
P 		338.7
(-3)
P 		583.5
(-1.9)
P 		849.7
(-0.7)
P 		1663.8
(3)
P 		1325
B 646.2
(-2)
P 		483.8
(-3)
P 		501.5
(-2.9)
P 		563.2
(-2.5)
P 		796.1
(-1)
P 		1441.5
(3)
P 		958
C 442.6
(-3)
P 		528.3
(-2.5)
P 		444.4
(-3)
P 		466.8
(-2.9)
P 		731.3
(-1.3)
P 		1440.4
(3)
P 		998
avr 550.5
(-2.3) 		504.9
(-2.6) 		428.2
(-3) 		537.8
(-2.4) 		792.4
(-1) 		1515.2
(3) 		1087
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 199
1 2 3 4 range
A 153.7
(1.2)
P 		170.5
(1.8)
P 		201.9
(3)
P 		42.6
(-3)
P 		159
B 162.8
(2.6)
P 		169.9
(3)
P 		159.2
(2.4)
P 		69
(-3)
P 		101
C 177.2
(1)
P 		237.6
(2.9)
P 		241.8
(3)
P 		48.3
(-3)
P 		194
avr 164.6
(1.5) 		192.7
(2.7) 		201
(3) 		53.3
(-3) 		148

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 464
1 2 3 4 5 6 range
A 103.7
(-2.5)
P 		178.7
(-1.1)
P 		73.8
(-3)
P 		148
(-1.7)
P 		256.4
(0.3)
P 		405.1
(3)
P 		331
B 224.8
(-1.5)
P 		161
(-2.4)
P 		121.8
(-3)
P 		149.2
(-2.6)
P 		323.4
(-0.1)
P 		537.5
(3)
P 		416
C 164.1
(-1.9)
P 		161.2
(-2)
P 		113.1
(-2.7)
P 		93.9
(-3)
P 		236.6
(-0.8)
P 		482.2
(3)
P 		388
avr 164.2
(-2) 		167
(-2) 		102.9
(-3) 		130.4
(-2.6) 		272.1
(-0.3) 		474.9
(3) 		372
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173808_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24377
Sequence Type Exemplar sequence
Representative Public ID CEK035BYR NCBI
Target Description CEK035BYR_rc /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=Y43F4B.6 /5_PRIME_EXT_DB=WormBase Gene ID /GB=D33723 /WB_GENE_ID=Y43F4B.6 /WP=CE16631 /CHR=3 /FEA=Genomic Cluster /DEF=Kinesin motor domain; C.elegans cDNA clone yk35b11 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067341(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067341 NCBI Caenorhabditis elegans Kinesin-Like Protein family member (klp-19) (klp-19) mRNA, complete cds. 11/11 None
SNAP00000007801 ENSEMBL cdna:SNAP chromosome:CEL140:III:13302537:13306708:-1 11/11 None
GENEFINDER00000007814 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:13302537:13306708:-1 11/11 None
Y43F4B.6 ENSEMBL cdna:known chromosome:CEL140:III:13302259:13306775:-1 gene:Y43F4B.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:13302265-13306705(-) 100.0 100.0
Public Domain and Genome References
Gene Title Kinesin motor domain
Gene Symbol klp-19
Ensembl Y43F4B.6
Entrez Gene 176750 Entrez gene
SwissProt O45935 EMBL-EBI
WormBase CE16631 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:247603_AT chromosome-associated kinesin, putative at
CANINE_2:CFAAFFX.25740.1.S1_S_AT similar to Chromosome-associated kinesin KIF4A (Chromokinesin) cfa
CANINE_2:CFAAFFX.25746.1.S1_AT similar to Chromosome-associated kinesin KIF4A (Chromokinesin) cfa
DROSOPHILA_2:1624632_AT Kinesin-like protein at 3A dm
DROSGENOME1:154060_AT Kinesin-like protein at 3A dm
CHICKEN:GGA.4358.1.S1_A_AT kinesin family member 4A gga
CHICKEN:GGA.4358.1.S1_AT kinesin family member 4A gga
CHICKEN:GGA.4358.2.S1_A_AT kinesin family member 4A gga
HG-U133_PLUS_2:218355_AT kinesin family member 4A hs
HG-U133A:218355_AT kinesin family member 4A hs
HG-FOCUS:218355_AT kinesin family member 4A hs
HG-U133A_2:218355_AT kinesin family member 4A hs
HU35KSUBA:W58247_S_AT kinesin family member 4A hs
U133_X3P:G7305204_3P_AT kinesin family member 4A hs
HG-U95B:51160_AT kinesin family member 4A hs
MG-U74AV2:104644_AT kinesin family member 4 mm
MU11KSUBA:D12646_S_AT kinesin family member 4 mm
MOE430A:1450692_AT kinesin family member 4 mm
MOUSE430A_2:1450692_AT kinesin family member 4 mm
MOUSE430_2:1450692_AT kinesin family member 4 mm
RG-U34A:RC_AA859926_AT kinesin family member 4 rn
RAE230A:1379479_AT kinesin family member 4 rn
RAT230_2:1379479_AT kinesin family member 4 rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5875 microtubule associated complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3774 motor activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA16335 Hypothetical protein Y43F4B.6 [Caenorhabditis elegans] ref|NP_499742.1| Kinesin-Like Protein family member (klp-19) [Caenorhabditis elegans] 0.0
blast CAE58433 Hypothetical protein CBG01568 [Caenorhabditis briggsae] 0.0
blast CAB75427 chromokinesin [Homo sapiens] 1.0E-110
Protein Domains
Database ID Description E-Value
scop a.2.7.Seryl-tRNA synthetase (SerRS) All alpha proteins; Long alpha-hairpin; tRNA-binding arm; Seryl-tRNA synthetase (SerRS) 8.19999980926514
scop a.2.7.Seryl-tRNA synthetase (SerRS) All alpha proteins; Long alpha-hairpin; tRNA-binding arm; Seryl-tRNA synthetase (SerRS) 7.90000009536743
Pfam IPR001752 EMBL-EBI Kinesin, motor region 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:173808_S_AT
gtgaccatggatgactcgagacaccaaaagcgcaaagatcactccctgttggctgttgag
atgaatcggacaactgatgacaatgtcaaaagacgagtggcgatgtctccaatcaaatgt
gacgatgatacccgtctaacagaagaagatgaagacattgaaaacgaggcaatgaacaat
gccaccttcgtcaaagattcgttcaattctgccactattgtgttggacgattcgcaaccg
tctccttccaactcaacattcgtgatcggtgcagctccaacgtcggaagcagacggtgtt
cctcccatcaagcgaaagagtcgtcgaacggatcttggaccgctcta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGACCATGGATGACTCGAGACACC 539 483 2918 Antisense
AAAAGCGCAAAGATCACTCCCTGTT 665 131 2943 Antisense
ATCACTCCCTGTTGGCTGTTGAGAT 561 27 2955 Antisense
ACGAGTGGCGATGTCTCCAATCAAA 94 93 3010 Antisense
GCAATGAACAATGCCACCTTCGTCA 544 321 3086 Antisense
AGATTCGTTCAATTCTGCCACTATT 518 65 3112 Antisense
TGTTGGACGATTCGCAACCGTCTCC 654 563 3138 Antisense
CAACATTCGTGATCGGTGCAGCTCC 319 189 3171 Antisense
CGTCGGAAGCAGACGGTGTTCCTCC 65 247 3198 Antisense
GTGTTCCTCCCATCAAGCGAAAGAG 506 485 3213 Antisense
GTCGAACGGATCTTGGACCGCTCTA 70 473 3240 Antisense
Sequence Source Affymetrix Proprietary Database