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[173698_s_at] Cytochrome P450

Description CEC1714 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F01D5.9 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C12171 /WB_GENE_ID=F01D5.9 /WP=CE18566 /CHR=2 /FEA=Genomic Cluster /DEF=Cytochrome P450; C.elegans cDNA clone yk147c9 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 12      4grp_highest_8_8 > 20      4grp_high_8_8 > 31      6grp_highest_nonorm > 22      6grp_total > 23      4grp_total > 24      6grp_highest_sub > De      6grp_cgc > 70      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1503
1 2 3 4 range
A 867.6
(-3)
P 		992.5
(-2.4)
P 		2019.9
(2.8)
P 		2063.7
(3)
P 		1196
B 693.5
(-3)
P 		1013.9
(-1.7)
P 		2156.2
(2.8)
P 		2196.1
(3)
P 		1503
C 780.6
(-3)
P 		1001.2
(-1.9)
P 		1872
(2.3)
P 		2006.2
(3)
P 		1226
avr 780.6
(-3) 		1002.5
(-2) 		2016
(2.7) 		2088.7
(3) 		1308

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1105
1 2 3 4 5 6 range
A 2027.9
(3)
P 		1648.9
(0.2)
P 		1729.6
(0.8)
P 		1484.1
(-1)
P 		1546
(-0.5)
P 		1208.9
(-3)
P 		819
B 2188.7
(3)
P 		1749.4
(0.6)
P 		1975.4
(1.8)
P 		1574.7
(-0.3)
P 		1514.3
(-0.7)
P 		1083.3
(-3)
P 		1105
C 1675.3
(1.3)
P 		1827.8
(2.5)
P 		1891.9
(3)
P 		1328.6
(-1.4)
P 		1632.5
(1)
P 		1122.6
(-3)
P 		769
avr 1964
(3) 		1742
(1.4) 		1865.6
(2.3) 		1462.5
(-0.6) 		1564.3
(0.1) 		1138.3
(-3) 		826
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 437
1 2 3 4 range
A 315.9
(-1.1)
P 		215.4
(-3)
P 		528.1
(3)
P 		302.1
(-1.3)
P 		313
B 221.2
(-3)
P 		250.4
(-2.4)
P 		499.6
(3)
P 		468
(2.3)
P 		278
C 258.4
(-3)
P 		287.9
(-2.6)
P 		652.5
(3)
P 		338.3
(-1.8)
P 		394
avr 265.2
(-2.7) 		251.2
(-3) 		560.1
(3) 		369.5
(-0.7) 		309

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 494
1 2 3 4 5 6 range
A 373.8
(-1.4)
P 		586.4
(3)
P 		376.7
(-1.3)
P 		376.4
(-1.3)
P 		466.5
(0.5)
P 		294.3
(-3)
P 		292
B 761.6
(3)
P 		582.3
(-0)
P 		479.7
(-1.7)
P 		417.1
(-2.8)
P 		615.3
(0.5)
P 		404
(-3)
P 		358
C 621
(3)
P 		557.7
(1.9)
P 		481.5
(0.6)
P 		267.2
(-3)
P 		528.3
(1.4)
P 		375.8
(-1.2)
P 		354
avr 585.5
(3) 		575.5
(2.7) 		446
(-0.6) 		353.6
(-3) 		536.7
(1.7) 		358
(-2.9) 		232
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173698_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23392
Sequence Type Exemplar sequence
Representative Public ID CEC1714 NCBI
Target Description CEC1714 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=F01D5.9 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C12171 /WB_GENE_ID=F01D5.9 /WP=CE18566 /CHR=2 /FEA=Genomic Cluster /DEF=Cytochrome P450; C.elegans cDNA clone yk147c9 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064538(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064538 NCBI Caenorhabditis elegans CYtochrome P450 family member (cyp-37A1) (cyp-37A1) mRNA, complete cds. 11/11 None
SNAP00000039845 ENSEMBL cdna:SNAP chromosome:CEL140:II:14013746:14020837:-1 11/11 None
GENEFINDER00000039846 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:14013746:14020850:-1 11/11 None
F01D5.9 ENSEMBL cdna:known chromosome:CEL140:II:14013717:14016856:-1 gene:F01D5.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:14013733-14016849(-) 99.94 100.0
Public Domain and Genome References
Gene Title Cytochrome P450
Gene Symbol cyp-37A1
Ensembl F01D5.9
Entrez Gene 175053 Entrez gene
SwissProt Q9XVA6 EMBL-EBI
WormBase CE35449 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04044 Hypothetical protein F01D5.9 [Caenorhabditis elegans] ref|NP_496939.2| CYtochrome P450 family member (cyp-37A1) [Caenorhabditis elegans] 0.0
blast CAE73389 Hypothetical protein CBG20829 [Caenorhabditis briggsae] 0.0
blast CAB04045 Hypothetical protein F01D5.10 [Caenorhabditis elegans] ref|NP_496940.1| F01D5.10 [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
p450 CP1B_RAT Animalia; CYP1B1; rat; CP1B_RAT; Rattus sp.; Q64678 1.0E-107
p450 CP11_CHACA Animalia; CYP1A; Chc; CP11_CHACA; Chaetodon capistratus; Q92039 1.0E-115
p450 CP11_CHACA Animalia; CYP1A; Chc; CP11_CHACA; Chaetodon capistratus; Q92039 1.0E-116
Protein Domains
Database ID Description E-Value
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.5E-99
Pfam IPR007669 EMBL-EBI Protein of unknown function DUF595 2.0E-20
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.5E-99
Pfam IPR007669 EMBL-EBI Protein of unknown function DUF595 2.0E-20
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.9E-94
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496939.2 1 2-20
F01D5.9 1 2-20
SNAP00000039845 1 50-67
GENEFINDER00000039846 3 55-72,372-394,406-428
Sequence
Target Sequence 
>C. ELEGANS:173698_S_AT
atgttcgaaggccatgacaccacctcggcaggcattggatggtccctgtggtgccttgca
aattgcccagagtatcagaaaaagtgccatgaggagttggatgagattttcgaggggaca
agcagagaatgcagtgtcgaggacttgaaaaaaatgaaatatttggaaaaatgcgtgaag
gaagcgttgagaatgcggccatcagtaccgcaaatggcgaggtcggtggaggaggaagtg
gaaattgacggcaaaatcctgcccaagggctgctccgtgatgatatcccctgcattcatc
cagaacaaccctcgaaccttcccgaaccacgaagtcttcgaccccgaaagattcaacgag
gatgagatctccaagcgccatgcgtatgcgtacattcctttcagtgcgggaccccgtaac
tgcatcgggcaaaagttcgcaatgcaggaggagaaaactgtgatctcttgggtcttgcga
cgatttcatattcacaccgatattgggctactggagaatatgccattgcccgagacgatc
acgagaccctctttgggatttcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTTCGAAGGCCATGACACCACCT 440 47 998 Antisense
CACCACCTCGGCAGGCATTGGATGG 541 201 1015 Antisense
CTGTGGTGCCTTGCAAATTGCCCAG 351 239 1043 Antisense
AAGGGCTGCTCCGTGATGATATCCC 446 159 1262 Antisense
TCCCCTGCATTCATCCAGAACAACC 49 597 1283 Antisense
ATCTCCAAGCGCCATGCGTATGCGT 56 33 1364 Antisense
TATGCGTACATTCCTTTCAGTGCGG 378 651 1382 Antisense
TTCAGTGCGGGACCCCGTAACTGCA 252 679 1397 Antisense
AAAACTGTGATCTCTTGGGTCTTGC 435 131 1451 Antisense
GCGACGATTTCATATTCACACCGAT 252 289 1474 Antisense
CACGAGACCCTCTTTGGGATTTCCA 543 197 1537 Antisense
Sequence Source Affymetrix Proprietary Database