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[173691_s_at]

Description AU111378 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK688.2 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AU111378 /WB_GENE_ID=ZK688.2 /WP=CE00460 /CHR=3 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk729b7 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 34      6grp_high1_10_10 > 43      4grp_highest_8_8 > 44      4grp_high_8_8 > 16      6grp_highest_nonorm > 62      6grp_total > 20      4grp_total > 39      6grp_highest_sub > 02_03      6grp_high1_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 412
1 2 3 4 range
A 722.3
(3)
P 		351.2
(-2.9)
P 		345.6
(-3)
P 		447.2
(-1.4)
P 		377
B 707.3
(3)
P 		310.8
(-3)
P 		403
(-1.6)
P 		505.2
(-0.1)
P 		397
C 616.5
(3)
P 		322.3
(-3)
P 		419.6
(-1)
P 		501.5
(0.7)
P 		294
avr 682
(3) 		328.1
(-3) 		389.4
(-2) 		484.6
(-0.3) 		354

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 442
1 2 3 4 5 6 range
A 386.1
(-2.7)
P 		604.7
(2.1)
P 		583.9
(1.6)
P 		645.5
(3)
P 		444.3
(-1.4)
P 		373.3
(-3)
P 		272
B 579.8
(-1.1)
P 		815.5
(3)
P 		588.8
(-0.9)
P 		522
(-2)
P 		506.4
(-2.3)
P 		466.5
(-3)
P 		349
C 462.1
(-2.2)
P 		734.1
(3)
P 		703.1
(2.4)
P 		495.2
(-1.6)
P 		467.2
(-2.1)
P 		420
(-3)
P 		314
avr 476
(-1.9) 		718.1
(3) 		625.3
(1.1) 		554.2
(-0.3) 		472.6
(-1.9) 		419.9
(-3) 		298
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 198
1 2 3 4 range
A 263
(3)
P 		76.2
(-2.7)
P 		90.3
(-2.2)
P 		65.5
(-3)
P 		198
B 225.6
(3)
P 		76.8
(-3)
P 		93.4
(-2.3)
P 		107.7
(-1.8)
P 		149
C 204.1
(3)
P 		92.7
(-2.6)
P 		146.3
(0.1)
P 		84.6
(-3)
P 		120
avr 230.9
(3) 		81.9
(-3) 		110
(-1.9) 		85.9
(-2.8) 		149

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 200
1 2 3 4 5 6 range
A 71.2
(-3)
P 		215.1
(3)
P 		127.2
(-0.7)
P 		163.7
(0.9)
P 		134.1
(-0.4)
P 		90.9
(-2.2)
P 		144
B 201.7
(-0.1)
P 		271.5
(3)
P 		143
(-2.8)
P 		138.3
(-3)
P 		205.8
(0)
P 		173.9
(-1.4)
P 		133
C 171.3
(0.5)
P 		224
(3)
P 		179
(0.8)
P 		99.6
(-3)
P 		151.2
(-0.5)
P 		140.6
(-1)
P 		124
avr 148.1
(-2.2) 		236.9
(3) 		149.7
(-2.1) 		133.9
(-3) 		163.7
(-1.3) 		135.1
(-2.9) 		103
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173691_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24285
Sequence Type Exemplar sequence
Representative Public ID AU111378 NCBI
Target Description AU111378 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=ZK688.2 /5_PRIME_EXT_DB=WormBase Gene ID /GB=AU111378 /WB_GENE_ID=ZK688.2 /WP=CE00460 /CHR=3 /FEA=Genomic Cluster /DEF=Caenorhabditis elegans cDNA clone:yk729b7 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066316(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066316 NCBI Caenorhabditis elegans ZK688.2 (ZK688.2) mRNA, complete cds. 11/11 None
SNAP00000043628 ENSEMBL cdna:SNAP chromosome:CEL140:III:7900959:7904159:1 11/11 None
GENEFINDER00000043645 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7900959:7904159:1 11/11 None
ZK688.2.2 ENSEMBL cdna:known chromosome:CEL140:III:7900955:7904328:1 gene:ZK688.2 11/11 None
ZK688.2.1 ENSEMBL cdna:known chromosome:CEL140:III:7900957:7904660:1 gene:ZK688.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7900957-7904158(+) 95.21 100.0
Public Domain and Genome References
Gene Title
Ensembl ZK688.2
Entrez Gene 176110 Entrez gene
SwissProt P34672 EMBL-EBI
WormBase CE00460 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.26310.1.S1_AT similar to Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1) cfa
DROSOPHILA_2:1627617_AT Bestrophin 1 dm
DROSGENOME1:141376_AT Bestrophin 1 dm
HG-U133_PLUS_2:207432_AT vitelliform macular dystrophy 2-like 1 hs
HG-U133A:207432_AT vitelliform macular dystrophy 2-like 1 hs
HG-U133A_2:207432_AT vitelliform macular dystrophy 2-like 1 hs
U133_X3P:G8923136_3P_AT vitelliform macular dystrophy 2-like 1 hs
HG-U95C:56890_AT Vitelliform macular dystrophy 2-like 1 hs
HU35KSUBD:RC_AA621745_AT Vitelliform macular dystrophy 2-like 1 hs
MOUSE430A_2:1425729_AT vitelliform macular dystrophy 2-like protein 1 mm
MOUSE430_2:1425729_AT vitelliform macular dystrophy 2-like protein 1 mm
MOE430A:1425729_AT vitelliform macular dystrophy 2-like protein 1 mm
RAE230B:1383584_AT vitelliform macular dystrophy 2-like protein 1 (predicted) rn
RAT230_2:1383584_AT vitelliform macular dystrophy 2-like protein 1 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAA28228 Hypothetical protein ZK688.2 [Caenorhabditis elegans] ref|NP_498717.1| ZK688.2 [Caenorhabditis elegans] sp|P34672|YO22_CAEEL Hypothetical protein ZK688.2 in chromosome III 0.0
blast CAE66881 Hypothetical protein CBG12260 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000615 EMBL-EBI Bestrophin 1.0E-126
Pfam IPR000615 EMBL-EBI Bestrophin 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498717.1 4 28-50,71-90,94-116,271-288
ZK688.2.2 4 28-50,71-90,94-116,271-288
ZK688.2.1 4 28-50,71-90,94-116,271-288
SNAP00000043628 4 28-50,71-90,94-116,271-288
GENEFINDER00000043645 4 28-50,71-90,94-116,287-304
Sequence
Target Sequence 
>C. ELEGANS:173691_S_AT
gagaggtcattctcgaaaccccatttacacgacgacctaggtcgaaagacgttctcacat
ggaatgcttgaaaacatggaatttgagggatcaaatacaaatattgcagatggatcccat
gcaaataacaattcattcacaaattcagcatttgtgaattcaggagaagacctttcaaat
aagcgaattgacacatcatccagtcagccacaactggcaactgggaaacgtggaagtgaa
catccattccaacatcacgtacttgacgacgtcttagaagacgatgaatcagatgagaat
cagttaacgattcggaagaaatcctctgttttgcaaccagcaattacattggttgaaaga
tttaatgaagctactggtcagttagaaactgaagtaaaaagagatgagaagaagaaaaaa
gaagaggaattgagagaagaaggagacaatggaaaagaagaaaaagataataaagaggat
aaaaaagaagaacaagagcgtccatcccgaccaactcgaccattcttcattggagtagtc
cgctcagaatctgaagatcatagccatccgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGAGGTCATTCTCGAAACCCCATT 545 393 1311 Antisense
TCTCGAAACCCCATTTACACGACGA 67 607 1321 Antisense
GACCTAGGTCGAAAGACGTTCTCAC 440 381 1344 Antisense
GACGTTCTCACATGGAATGCTTGAA 251 379 1358 Antisense
TTGACACATCATCCAGTCAGCCACA 606 703 1498 Antisense
TGAACATCCATTCCAACATCACGTA 337 573 1547 Antisense
ACATCACGTACTTGACGACGTCTTA 362 105 1562 Antisense
GAAATCCTCTGTTTTGCAACCAGCA 135 363 1628 Antisense
GACCAACTCGACCATTCTTCATTGG 420 383 1819 Antisense
TCTTCATTGGAGTAGTCCGCTCAGA 264 617 1834 Antisense
GAATCTGAAGATCATAGCCATCCGC 336 327 1857 Antisense
Sequence Source Affymetrix Proprietary Database