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[173665_at]

Description C46445 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=T26A5.9 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C46445 /WB_GENE_ID=T26A5.9 /WP=CE00788 /CHR=3 /FEA=Genomic Cluster /GEN=dlc-1 /DEF=C.elegans cDNA clone yk418c6 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 33      6grp_high1_10_10 > 22      4grp_highest_8_8 > 10      4grp_high_8_8 > 54      6grp_highest_nonorm > 37      6grp_total > 31      4grp_total > 57      6grp_highest_sub > 02      6grp_cgc > 62      6grp_high1_sub > De      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5544
1 2 3 4 range
A 4641.6
(-1.6)
P 		6628.2
(1)
P 		8111.3
(3)
P 		3578.5
(-3)
P 		4533
B 3947.1
(-2.2)
P 		7445.2
(2)
P 		8276.6
(3)
P 		3237.3
(-3)
P 		5039
C 4406.9
(-0.9)
P 		6787.9
(2.1)
P 		7494.6
(3)
P 		2732.9
(-3)
P 		4762
avr 4331.9
(-1.6) 		6953.8
(1.7) 		7960.8
(3) 		3182.9
(-3) 		4778

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1638
1 2 3 4 5 6 range
A 4892.8
(-0.5)
P 		5567
(3)
P 		5031
(0.3)
P 		4771.5
(-1.1)
P 		4704.8
(-1.4)
P 		4396.3
(-3)
P 		1171
B 5202.6
(1.2)
P 		5668.6
(3)
P 		5574.6
(2.6)
P 		5171.6
(1.1)
P 		4505.3
(-1.5)
P 		4127.8
(-3)
P 		1541
C 5262.9
(0.8)
P 		5177.5
(0.4)
P 		5264.2
(0.8)
P 		5765.8
(3)
P 		4566
(-2.2)
P 		4382.6
(-3)
P 		1383
avr 5119.4
(1.2) 		5471
(3) 		5289.9
(2.1) 		5236.3
(1.8) 		4592
(-1.5) 		4302.2
(-3) 		1169
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2151
1 2 3 4 range
A 1690
(1.4)
P 		1438.8
(0.4)
P 		2120.5
(3)
P 		523.8
(-3)
P 		1597
B 1258.7
(-0.2)
P 		1838.8
(2.6)
P 		1917.9
(3)
P 		689.9
(-3)
P 		1228
C 1458.8
(-0.2)
P 		1951.6
(1.2)
P 		2612.1
(3)
P 		460.8
(-3)
P 		2151
avr 1469.2
(0.3) 		1743.1
(1.3) 		2216.8
(3) 		558.2
(-3) 		1659

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1078
1 2 3 4 5 6 range
A 902
(-3)
P 		1979.9
(3)
P 		1095.7
(-1.9)
P 		1210.2
(-1.3)
P 		1419.7
(-0.1)
P 		1070.4
(-2.1)
P 		1078
B 1810.2
(2.1)
P 		1886.8
(3)
P 		1353.7
(-3)
P 		1369.8
(-2.8)
P 		1830.4
(2.4)
P 		1539.3
(-0.9)
P 		533
C 1950.7
(3)
P 		1579.8
(0.2)
P 		1339.8
(-1.6)
P 		1159.5
(-3)
P 		1477.5
(-0.6)
P 		1467.1
(-0.7)
P 		791
avr 1554.3
(0.2) 		1815.5
(3) 		1263.1
(-2.8) 		1246.5
(-3) 		1575.9
(0.5) 		1358.9
(-1.8) 		569
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173665_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23877
Sequence Type Exemplar sequence
Representative Public ID C46445 NCBI
Target Description C46445 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=T26A5.9 /5_PRIME_EXT_DB=WormBase Gene ID /GB=C46445 /WB_GENE_ID=T26A5.9 /WP=CE00788 /CHR=3 /FEA=Genomic Cluster /GEN=dlc-1 /DEF=C.elegans cDNA clone yk418c6 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066021(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066021 NCBI Caenorhabditis elegans Dynein Light Chain family member (dlc-1) (dlc-1) mRNA, complete cds. 11/11 None
T26A5.9.1 ENSEMBL cdna:known chromosome:CEL140:III:6462842:6463716:-1 gene:T26A5.9 11/11 A 
T26A5.9.3 ENSEMBL cdna:known chromosome:CEL140:III:6462842:6463718:-1 gene:T26A5.9 11/11 None
T26A5.9.2 ENSEMBL cdna:known chromosome:CEL140:III:6462844:6463738:-1 gene:T26A5.9 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:6462909-6463701(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol dlc-1
Ensembl T26A5.9
Entrez Gene 175922 Entrez gene
SwissProt Q22799 EMBL-EBI
WormBase CE00788 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1599394_AT similar to dynein light chain-2 cfa
CANINE:1597656_AT similar to dynein light chain-2 cfa
CANINE:1590826_AT similar to dynein light chain-2 cfa
CANINE_2:CFA.11586.1.A1_S_AT similar to dynein light chain-2 cfa
DROSOPHILA_2:1634599_S_AT cut up dm
DROSOPHILA_2:1623073_S_AT cut up dm
DROSGENOME1:154226_AT cut up dm
CHICKEN:GGA.17308.1.S1_S_AT similar to dynein light chain-2 gga
CHICKEN:GGA.3112.1.S1_AT similar to dynein light chain-2 gga
HG-U133_PLUS_2:229106_AT dynein light chain 2 hs
HG-U133B:229106_AT dynein light chain 2 hs
HU35KSUBC:RC_AA401429_AT dynein light chain 2 hs
HG-U95B:46139_AT dynein light chain 2 hs
HG-U133_PLUS_2:225494_AT Dynein light chain 2 hs
HG-U133B:225494_AT Dynein light chain 2 hs
HG-U95B:43071_AT Dynein light chain 2 hs
HG-U95B:44688_AT Dynein light chain 2 hs
HU35KSUBA:AA464334_S_AT Dynein light chain 2 hs
U133_X3P:HS.7811.1.A1_3P_A_AT Dynein light chain 2 hs
U133_X3P:HS.7811.1.A1_3P_X_AT Dynein light chain 2 hs
HU35KSUBD:RC_H41659_R_AT Dynein light chain 2 hs
MOUSE430_2:1418258_S_AT RIKEN cDNA 6720463E02 gene mm
MOE430A:1418258_S_AT RIKEN cDNA 6720463E02 gene mm
MOUSE430A_2:1418258_S_AT RIKEN cDNA 6720463E02 gene mm
MU11KSUBA:AA518692_F_AT RIKEN cDNA 6720463E02 gene mm
MU11KSUBA:AA237797_F_AT RIKEN cDNA 6720463E02 gene mm
MG-U74AV2:101929_AT RIKEN cDNA 6720463E02 gene mm
MG-U74BV2:109710_AT RIKEN cDNA 6720463E02 gene mm
MG-U74AV2:161960_F_AT RIKEN cDNA 6720463E02 gene mm
MG-U74CV2:169700_AT RIKEN cDNA 6720463E02 gene mm
MOE430A:1418371_AT RIKEN cDNA 6720463E02 gene mm
MOUSE430A_2:1418371_AT RIKEN cDNA 6720463E02 gene mm
MOUSE430_2:1418371_AT RIKEN cDNA 6720463E02 gene mm
MU19KSUBA:TC17558_S_AT RIKEN cDNA 6720463E02 gene (6720463E02Rik), mRNA mm
MU19KSUBA:TC19255_F_AT RIKEN cDNA 6720463E02 gene (6720463E02Rik), mRNA mm
MU19KSUBB:TC34362_AT RIKEN cDNA 6720463E02 gene (6720463E02Rik), mRNA mm
RG-U34B:RC_AI011489_S_AT dynein light chain-2 rn
RG-U34C:RC_AI103774_AT dynein light chain-2 rn
RG-U34C:RC_AI177125_AT dynein light chain-2 rn
RG-U34C:RC_AI175114_AT dynein light chain-2 rn
RAE230A:1372612_AT dynein light chain-2 rn
RAT230_2:1372612_AT dynein light chain-2 rn
RAE230A:1387782_AT dynein light chain-2 rn
RAT230_2:1387782_AT dynein light chain-2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7017 microtubule-based process inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5875 microtubule associated complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3777 microtubule motor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_498422 Dynein Light Chain family member (dlc-1) [Caenorhabditis elegans] gb|AAC77510.1| Dynein light chain protein 1 [Caenorhabditis elegans] sp|Q22799|DYL1_CAEEL Dynein light chain 1, cytoplasmic emb|CAE72503.1| Hypothetical protein CBG19682 [Caenorhabditis briggsae] 7.0E-47
blast AAH90543 Dynein light chain 2, like [Danio rerio] ref|NP_001025171.1| dynein light chain 2, like [Danio rerio] gb|AAH56312.1| Dynein light chain (10.3 kD) (dlc-1) [Danio rerio] ref|XP_684913.1| PREDICTED: similar to Dynein light chain (10.3 kD) (dlc-1) isoform 1 [Danio rerio] ref|NP_956393.1| dynein light chain (10.3 kD) (dlc-1) [Danio rerio] emb|CAG08960.1| unnamed protein product [Tetraodon nigroviridis] 1.0E-45
blast NP_080832 dynein light chain 2 [Mus musculus] gb|AAI05141.1| Unknown (protein for MGC:127196) [Bos taurus] gb|AAH40822.1| Dynein light chain 2 [Mus musculus] gb|AAH10744.1| Dynein light chain 2 [Homo sapiens] ref|XP_866905.1| PREDICTED: similar to dynein light chain-2 isoform 8 [Canis familiaris] ref|XP_866896.1| PREDICTED: similar to dynein light chain-2 isoform 7 [Canis familiaris] ref|XP_866886.1| PREDICTED: similar to dynein light chain-2 isoform 6 [Canis familiaris] ref|XP_866875.1| PREDICTED: similar to dynein light chain-2 isoform 5 [Canis familiaris] ref|XP_866865.1| PREDICTED: similar to dynein light chain-2 isoform 4 [Canis familiaris] ref|XP_866856.1| PREDICTED: similar to dynein light chain-2 isoform 3 [Canis familiaris] ref|XP_537691.2| PREDICTED: similar to dynein light chain-2 isoform 1 [Canis familiaris] emb|CAI25730.1| dynein light chain 2 [Mus musculus] gb|AAH61874.1| Dynein light chain-2 [Rattus norvegicus] gb|AAH11289.1| Dynein light chain 2 [Mus musculus] dbj|BAE35638.1| unnamed protein product [Mus musculus] dbj|BAE40984.1| unnamed protein product [Mus musculus] gb|AAP97230.1| protein inhibitor of neuronal nitric oxide synthase [Homo sapiens] dbj|BAC33856.1| unnamed protein product [Mus musculus] dbj|BAC25877.1| unnamed protein product [Mus musculus] dbj|BAB27516.1| unnamed protein product [Mus musculus] dbj|BAC37271.1| unnamed protein product [Mus musculus] gb|AAK57536.1| dynein light chain-2 [Rattus norvegicus] gb|AAK38749.1| dynein light chain 2 [Mus musculus] ref|NP_542408.1| dynein light chain 2 [Homo sapiens] ref|NP_542428.1| dynein light chain-2 [Rattus norvegicus] sp|Q9D0M5|DYL2_MOUSE Dynein light chain 2, cytoplasmic (8 kDa dynein light chain) (DLC8) (DLC8b) sp|Q96FJ2|DYL2_HUMAN Dynein light chain 2, cytoplasmic sp|Q78P75|DYL2_RAT Dynein light chain 2, cytoplasmic gb|AAH88794.1| LOC496257 protein [Xenopus laevis] pdb|1PWJ|A Chain A, Structure Of The Monomeric 8-Kda Dynein Light Chain And Mechanism Of Domain Swapped Dimer Assembly 2.0E-45
Protein Domains
Database ID Description E-Value
Pfam IPR001372 EMBL-EBI Dynein light chain, type 1 2.4E-65
Sequence
Target Sequence 
>C. ELEGANS:173665_AT
gataaatcccatcctgttcttaaaaaacattcaatgatctttaaattgtgacctgatcct
acgtgtaccttaggtggcgtaggatcttcagtgtgcactcttgttaaatcttccttttcc
tcccaaaaaacattttccttcgtcgcattctatttatttagctcaaactgttcattttct
ttgaatcttcctccatcacccataaatcttcttac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATAAATCCCATCCTGTTCTTAAAA 544 423 279 Antisense
AATTGTGACCTGATCCTACGTGTAC 138 179 322 Antisense
GATCCTACGTGTACCTTAGGTGGCG 671 413 333 Antisense
GGTGGCGTAGGATCTTCAGTGTGCA 352 499 351 Antisense
GGATCTTCAGTGTGCACTCTTGTTA 518 511 360 Antisense
GCACTCTTGTTAAATCTTCCTTTTC 641 315 373 Antisense
CAAAAAACATTTTCCTTCGTCGCAT 358 189 402 Antisense
CGTCGCATTCTATTTATTTAGCTCA 682 245 419 Antisense
TTAGCTCAAACTGTTCATTTTCTTT 294 681 436 Antisense
TCATTTTCTTTGAATCTTCCTCCAT 395 619 450 Antisense
CTCCATCACCCATAAATCTTCTTAC 27 237 469 Antisense
Sequence Source Affymetrix Proprietary Database