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[173504_at]

Description g416296 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=C42D8.8 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=C42D8.8 /WP=CE04209 /CHR=X /FEA=Genomic Cluster /GEN=APL-1 /DEF=beta-amyloid protein precursor; locus:uvt-4 (ST.LOUIS) TR:Q10651 protein_id:AAA98722.1
Cluster 6grp_highest_10_10 > 52      6grp_high1_10_10 > 25      4grp_highest_8_8 > 37      4grp_high_8_8 > 0      6grp_highest_nonorm > 05      6grp_total > 27      4grp_total > 07      6grp_highest_sub > 01_02      6grp_cgc > 04      6grp_high1_sub > 01_02      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5896
1 2 3 4 range
A 10010.6
(3)
P 		4114.2
(-3)
P 		6286.7
(-0.8)
P 		7871.4
(0.8)
P 		5896
B 5943.1
(-3)
P 		6502.8
(-1.6)
P 		7089.9
(-0.2)
P 		8374.9
(3)
P 		2432
C 8656.3
(3)
P 		5179.5
(-3)
P 		6383.6
(-0.9)
P 		8356
(2.5)
P 		3477
avr 8203.3
(3) 		5265.5
(-3) 		6586.7
(-0.3) 		8200.8
(3) 		2938

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 5236
1 2 3 4 5 6 range
A 7853.7
(3)
P 		6077.4
(-0.3)
P 		4655.2
(-3)
P 		4671.5
(-3)
P 		6207.8
(-0.1)
P 		5540.5
(-1.3)
P 		3199
B 6571.8
(1.4)
P 		7750.5
(3)
P 		3454.2
(-3)
P 		5357.2
(-0.3)
P 		5499.1
(-0.1)
P 		5571.4
(-0)
P 		4296
C 6149.4
(-0)
P 		8689.8
(3)
P 		4985.1
(-1.4)
P 		3676.9
(-3)
P 		4715.9
(-1.8)
P 		4803.5
(-1.7)
P 		5013
avr 6858.3
(1.8) 		7505.9
(3) 		4364.8
(-3) 		4568.5
(-2.6) 		5474.3
(-0.9) 		5305.1
(-1.2) 		3141
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2752
1 2 3 4 range
A 3644.9
(3)
P 		893.1
(-3)
P 		1643.5
(-1.4)
P 		1152.2
(-2.4)
P 		2752
B 1895.2
(3)
P 		1606
(-3)
P 		1642.9
(-2.2)
P 		1784.7
(0.7)
P 		289
C 2865.5
(3)
P 		1489.1
(-2.7)
P 		2224.9
(0.4)
P 		1409
(-3)
P 		1457
avr 2801.9
(3) 		1329.4
(-3) 		1837.1
(-0.9) 		1448.6
(-2.5) 		1473

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1912
1 2 3 4 5 6 range
A 1447.8
(-0.7)
P 		2161.4
(3)
P 		1013.8
(-3)
P 		1184.8
(-2.1)
P 		1873.2
(1.5)
P 		1348.9
(-1.2)
P 		1148
B 2286.7
(2)
P 		2579.8
(3)
P 		838.8
(-3)
P 		1418.9
(-1)
P 		2234.2
(1.8)
P 		2077.6
(1.3)
P 		1741
C 2279.3
(1.8)
P 		2651.5
(3)
P 		1268.8
(-1.3)
P 		739.4
(-3)
P 		1526
(-0.5)
P 		1608
(-0.3)
P 		1912
avr 2004.6
(1.1) 		2464.2
(3) 		1040.5
(-3) 		1114.4
(-2.7) 		1877.8
(0.5) 		1678.2
(-0.3) 		1424
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173504_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25786
Sequence Type Exemplar sequence
Representative Public ID 416296 NCBI
Target Description g416296 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=C42D8.8 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=C42D8.8 /WP=CE04209 /CHR=X /FEA=Genomic Cluster /GEN=APL-1 /DEF=beta-amyloid protein precursor; locus:uvt-4 (ST.LOUIS) TR:Q10651 protein_id:AAA98722.1
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076470(11), NM_076469(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076470 NCBI Caenorhabditis elegans Amyloid Precursor-Like family member (apl-1) (apl-1) mRNA, complete cds. 11/11 None
NM_076469 NCBI Caenorhabditis elegans Amyloid Precursor-Like family member (apl-1) (apl-1) mRNA, complete cds. 11/11 A 
C42D8.8b.1 ENSEMBL cdna:known chromosome:CEL140:X:5112389:5117309:-1 gene:C42D8.8 11/11 A 
C42D8.8b.2 ENSEMBL cdna:known chromosome:CEL140:X:5112389:5116833:-1 gene:C42D8.8 11/11 A 
C42D8.8b.4 ENSEMBL cdna:known chromosome:CEL140:X:5112389:5116838:-1 gene:C42D8.8 11/11 A 
C42D8.8a ENSEMBL cdna:known chromosome:CEL140:X:5112391:5116831:-1 gene:C42D8.8 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
C42D8.8b.3 7/11 Cross Hyb Matching Probes A 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:5112416-5116833(-) 98.23 100.0
Public Domain and Genome References
Ensembl C42D8.8
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_508871 Amyloid Precursor-Like family member (apl-1) [Caenorhabditis elegans] gb|AAK68242.1| Amyloid precursor-like protein 1, isoform b [Caenorhabditis elegans] 0.0
blast NP_508870 Amyloid Precursor-Like family member (apl-1) [Caenorhabditis elegans] gb|AAA98722.1| Amyloid precursor-like protein 1, isoform a [Caenorhabditis elegans] sp|Q10651|A4_CAEEL Beta-amyloid-like protein precursor 0.0
blast AAC46470 beta-amyloid protein precursor 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008154 EMBL-EBI Amyloid A4 extracellular region 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508871.1 1 617-639
NP_508870.3 1 619-641
C42D8.8b.1 1 617-639
C42D8.8b.2 1 617-639
C42D8.8b.4 1 617-639
C42D8.8a 1 619-641
Sequence
Target Sequence 
>C. ELEGANS:173504_AT
tccccgtagctgtttcgtcataacaacaaaaaccggacactcatgcttgttgttcgtatt
ttttgatatcgatctatccgtttcacacgaactaaattgaatataattcacgtgttttta
gtattcagaagcaccgatcacctttctatttttccaactcattattcttttcttcaacac
ttcctaaccaccccgatcttgaaatacaccctatttcttgtgatagtcttattatgcaca
cttctctctgtcttccgatttgctcgtttactgagtttatttcttaagaaagtcaacaaa
catttgtattaataaagaagtccaaagatgaatttgcatcccaatatgcttctaaacttt
tttcgtttcacacattttattgtcgtgaacttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCCCGTAGCTGTTTCGTCATAACA 342 589 2296 Antisense
AAAACCGGACACTCATGCTTGTTGT 181 131 2324 Antisense
CACTCATGCTTGTTGTTCGTATTTT 32 199 2333 Antisense
GATATCGATCTATCCGTTTCACACG 527 425 2360 Antisense
GATCTATCCGTTTCACACGAACTAA 62 421 2366 Antisense
GTCTTCCGATTTGCTCGTTTACTGA 479 465 2545 Antisense
GCTCGTTTACTGAGTTTATTTCTTA 419 295 2557 Antisense
GAATTTGCATCCCAATATGCTTCTA 648 325 2625 Antisense
ATCCCAATATGCTTCTAAACTTTTT 96 39 2633 Antisense
TTTTTTCGTTTCACACATTTTATTG 651 675 2653 Antisense
CACACATTTTATTGTCGTGAACTTC 208 195 2664 Antisense
Sequence Source GenBank