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[173479_at]

Description g5019818 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=R151.6 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=R151.6 /WP=CE00828 /CHR=3 /FEA=Genomic Cluster /GEN=R151.6 /DEF=putative NADH oxidoreductase complex I subunit
Cluster 6grp_highest_10_10 > 92      6grp_high1_10_10 > 49      4grp_highest_8_8 > 27      4grp_high_8_8 > 63      6grp_highest_nonorm > 81      6grp_total > 39      4grp_total > 56      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 236
1 2 3 4 range
A 231
(-3)
P 		285.3
(-0.9)
P 		388.9
(3)
P 		350.1
(1.5)
P 		158
B 324
(-3)
P 		357.4
(-0.8)
P 		415.6
(3)
P 		327.4
(-2.8)
P 		92
C 466.8
(3)
P 		353.1
(-0.4)
P 		345.9
(-0.6)
P 		267.5
(-3)
P 		199
avr 340.6
(-0.8) 		331.9
(-1.5) 		383.5
(3) 		315
(-3) 		69

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 209
1 2 3 4 5 6 range
A 257.2
(-1.1)
P 		236.7
(-1.8)
P 		199.8
(-3)
P 		247
(-1.4)
P 		382.4
(3)
P 		305.3
(0.5)
P 		183
B 347
(3)
P 		257.1
(-0.1)
P 		173.5
(-3)
P 		308.5
(1.7)
P 		297
(1.3)
P 		281.1
(0.7)
P 		174
C 313.8
(3)
P 		244.9
(-2.3)
P 		252.8
(-1.7)
P 		235.5
(-3)
P 		300.4
(2)
P 		297.6
(1.8)
P 		78
avr 306
(2) 		246.2
(-1.1) 		208.7
(-3) 		263.7
(-0.2) 		326.6
(3) 		294.7
(1.4) 		118
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 109
1 2 3 4 range
A 84.1
(0.9)
P 		61.9
(-1.7)
P 		101.7
(3)
P 		51.2
(-3)
P 		51
B 103.3
(3)
P 		88.3
(0.3)
P 		96.3
(1.7)
P 		69.8
(-3)
P 		34
C 154.5
(3)
P 		101.5
(0.1)
P 		120.5
(1.1)
P 		45.1
(-3)
P 		109
avr 114
(3) 		83.9
(-0.1) 		106.2
(2.2) 		55.4
(-3) 		59

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 79
1 2 3 4 5 6 range
A 47.4
(-2.7)
P 		84.2
(0.4)
P 		43.5
(-3)
P 		62.6
(-1.4)
P 		115.4
(3)
P 		74.3
(-0.4)
P 		72
B 120.7
(3)
P 		85.6
(0.3)
P 		42.1
(-3)
P 		81.7
(0)
P 		120.7
(3)
P 		104.8
(1.8)
P 		79
C 116.3
(3)
P 		74.7
(-0.6)
P 		64.3
(-1.5)
P 		47.4
(-3)
P 		97.2
(1.3)
P 		99.6
(1.5)
P 		69
avr 94.8
(1.4) 		81.5
(0.1) 		50
(-3) 		63.9
(-1.6) 		111.1
(3) 		92.9
(1.2) 		61
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173479_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24061
Sequence Type Exemplar sequence
Representative Public ID 5019818 NCBI
Target Description g5019818 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=R151.6 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=R151.6 /WP=CE00828 /CHR=3 /FEA=Genomic Cluster /GEN=R151.6 /DEF=putative NADH oxidoreductase complex I subunit
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066189(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066189 NCBI Caenorhabditis elegans R151.6 (R151.6) mRNA, complete cds. 11/11 A 
R151.6.2 ENSEMBL cdna:known chromosome:CEL140:III:7221664:7223053:-1 gene:R151.6 11/11 None
R151.6.1 ENSEMBL cdna:known chromosome:CEL140:III:7221684:7223053:-1 gene:R151.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7221747-7223022(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl R151.6
Entrez Gene 176018 Entrez gene
SwissProt Q21997 EMBL-EBI
WormBase CE00828 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17903_AT Der1-like family protein / degradation in the ER-like family protein at
ATH1-121501:255303_AT Der1-like family protein / degradation in the ER-like family protein at
CANINE_2:CFA.3368.1.S1_AT similar to Der1-like domain family, member 2 cfa
CANINE_2:CFAAFFX.23819.1.S1_AT similar to Der1-like domain family, member 2 cfa
DROSOPHILA_2:1623458_AT dm
DROSGENOME1:150021_AT dm
CHICKEN:GGA.6232.1.S1_AT similar to carcinoma related gene gga
HU35KSUBA:RC_AA393808_AT Der1-like domain family, member 2 hs
HG-U133A:218333_AT Der1-like domain family, member 2 hs
HG-U133_PLUS_2:218333_AT Der1-like domain family, member 2 hs
HG-U133A_2:218333_AT Der1-like domain family, member 2 hs
U133_X3P:G7705603_3P_AT Der1-like domain family, member 2 hs
HG-U95B:54635_AT Der1-like domain family, member 2 hs
MU11KSUBA:AA104485_S_AT Der1-like domain family, member 2 mm
MG-U74AV2:162116_R_AT Der1-like domain family, member 2 mm
MG-U74AV2:160769_AT Der1-like domain family, member 2 mm
MG-U74BV2:163577_AT Der1-like domain family, member 2 mm
MOE430A:1435101_AT Der1-like domain family, member 2 mm
MOUSE430A_2:1435101_AT Der1-like domain family, member 2 mm
MOUSE430_2:1435101_AT Der1-like domain family, member 2 mm
MOE430A:1448438_AT Der1-like domain family, member 2 mm
MOUSE430A_2:1448438_AT Der1-like domain family, member 2 mm
MOUSE430_2:1448438_AT Der1-like domain family, member 2 mm
MU19KSUBA:TC24566_AT Der1-like domain family, member 2 (Derl2), mRNA mm
Protein Similarities
Method ID Description E-Value
blast AAK29854 Hypothetical protein R151.6 [Caenorhabditis elegans] ref|NP_498590.3| R151.6 [Caenorhabditis elegans] 1.0E-105
blast AAD37863 putative NADH oxidoreductase complex I subunit [Caenorhabditis elegans] sp|Q21997|DERL2_CAEEL Derlin-2 (DER1-like protein 2) (cDerlin-2) 1.0E-105
blast CAE57605 Hypothetical protein CBG00586 [Caenorhabditis briggsae] 7.0E-95
Protein Domains
Database ID Description E-Value
Pfam IPR007599 EMBL-EBI Der1-like domain 1.2E-115
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498590.3 5 10-32,45-67,87-109,130-152,157-179
R151.6.2 5 10-32,45-67,87-109,130-152,157-179
R151.6.1 5 10-32,45-67,87-109,130-152,157-179
Sequence
Target Sequence 
>C. ELEGANS:173479_AT
ttagtatttttgaagttagacatctatttcgcgactgaacgtataattttctcatattac
ctaattattattttctctgctcttaatttttgaattcactcgtgggtctctatcggttgt
ccttccatcattctacgttttctgtgaatattctctcgcaattcta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTAGTATTTTTGAAGTTAGACATCT 33 683 710 Antisense
GTTAGACATCTATTTCGCGACTGAA 314 447 724 Antisense
GACATCTATTTCGCGACTGAACGTA 692 369 728 Antisense
TTTCGCGACTGAACGTATAATTTTC 118 667 736 Antisense
AATTTTCTCATATTACCTAATTATT 397 175 754 Antisense
ATTATTATTTTCTCTGCTCTTAATT 84 15 773 Antisense
TATTTTCTCTGCTCTTAATTTTTGA 160 663 778 Antisense
TCTGCTCTTAATTTTTGAATTCACT 376 609 785 Antisense
TGAATTCACTCGTGGGTCTCTATCG 624 575 800 Antisense
CATCATTCTACGTTTTCTGTGAATA 462 213 835 Antisense
CTGTGAATATTCTCTCGCAATTCTA 310 239 851 Antisense
Sequence Source GenBank